@RosenblattLab

Cell extrusion specialists 🥼 We're a bunch of cell biologists studying how cell extrusion impacts #asthma and #cancer 🔬🇬🇧

 King's College London
rosenblattlab.com/
Joined August 2019
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  • Following450
  • Followers580
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Interview with Stem Babe at the Royal Society youtu.be/Uc9rvuFlCSc?si=ZtI-…
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Rosenblatt Lab retweeted
nature
@Nature15 Sep 2025
Nature research paper: Energy deficiency selects crowded live epithelial cells for extrusion go.nature.com/4n3M3Q2

Energy deficiency selects crowded live epithelial cells for extrusion

Nature - Crowded epithelial cells with the least energy and membrane potential are selected for extrusion.

nature.com
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Our paper showing epithelial cells measure electrical potential to decide which ones to eliminate by extrusion came out today in Nature. The weakest link: how cells use electricity to eliminate their neighbours to maintain healthy barriers @TheCrick crick.ac.uk/news/2025-09-10_…
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Hero alert. My amazing colleague Carola Vinuesa used Science to get a wrongfully imprisoned woman freed after 20 years. The culprit: a mutation youtu.be/KExw3EQuu5s?si=33uz…
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crick.ac.uk/news/2025-07-01_…

Jody Rosenblatt Elected to the EMBO Membership

Jody Rosenblatt, Principal Group Leader at the Crick and Professor of Cell Biology at King’s College London, has been elected to the EMBO Membership in recognition of her outstanding scientific...

crick.ac.uk
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Very proud for our newly minted Dr. Faith Fore--that's Dr.4 to you!
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Thrilled & incredibly honoured to receive a @wellcometrust Early-Career Award! 🙌 Can't wait to start my research on how epithelial tissues maintain homeostasis at @TheCrick, @KingsCollegeLon & the @RosenblattLab! 🧪🔬🐟 Stay tuned - I’ll be hiring soon!
Headshot of Konstantinos Kalyviotis at the Francis Crick Institute

ALT Headshot of Konstantinos Kalyviotis at the Francis Crick Institute

Screenshots of the Wellcome Trust Early-Career Award funded application

ALT Screenshots of the Wellcome Trust Early-Career Award funded application

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Check out our recent review with Paul Martin & Gisli Jenkins on how imperfect wound healing can set the stage for disease, discussing how environment and general wear and tear we accumulate with age contributes to many diseases. science.org/doi/10.1126/scie…

Imperfect wound healing sets the stage for chronic diseases

Although the age of the genome gave us much insight about how our organs fail with disease, it also suggested that diseases do not arise from mutations alone; rather, they develop as we age. In this...

science.org
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Please share: we're listing a cherry of a project here and we'd like to recruit!
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Excited to recruit!
CRUKCOLcentre@CRUKCOLcentre2 Oct 2024
Are you interested in doing a #PhD in #cancerresearch & #biotherapeutics? Are you of black heritage? 🔬👩🏿‍🔬👨🏿‍🔬🧫🧪 Applications for our 4-year PhD programme for Black Leaders in Cancer are open now! @TheCrick @uclcancer @QMBCI @KingsCollegeLon colcc.ac.uk/black-leaders-ph…

Black Leaders PhD Recruitment Process

The CRUK CoL Centre Black Leaders in Cancer PhD Programme Applications for the CRUK CoL Centre Black Leader in Cancer PhD programme starting in September 2027 are open Application through Cancer...

colcc.ac.uk
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Imagine a world where beach and science are fused.. you don't have to dream...
Canalitos y Mandangas@vermelloverd19 Sep 2024
Join us! Mechanosignalling, ion channels, and neurodegenerative diseases. Nice building, even nicer people. Barcelona and all that. Publicly funded health care. Bike to work. By the beach. C'mon!
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Congratulations to our incoming director Edith Heard, current director of @embl, on being awarded the Croonian Medal from the @royalsociety 🏅 Learn more about Edith’s research and her recent award 👇 crick.ac.uk/news/2024-08-28_…

Edith Heard awarded Croonian Medal and Lecture from the Royal Society

Edith Heard, incoming Crick chief executive, has been awarded the Croonian Medal and Lecture from the Royal Society for being a leading figure in X chromosome biology. 

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Very proud of our own Snezkha Oliferenko for becoming an EMBO member! kcl.ac.uk/news/professor-sne…

Professor Snezhana Oliferenko elected to EMBO Membership | King's College London

In EMBO’s 60th anniversary year, 100 new Members and 20 Associate Members join the EMBO community

kcl.ac.uk
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We are delighted to announce that Professor Edith Heard has been appointed as our new director and chief executive! Edith, who is currently director-general at @EMBL, will succeed Paul Nurse in leading the Crick from the summer of 2025. 🔗 crick.ac.uk/news/2024-07-09_…
"The Francis Crick Institute has quickly established a global reputation for its work at the frontiers of science. I relish the challenge of building on that work. I also want to pay tribute to Sir Paul Nurse, without whom the Francis Crick Institute would not be the world-leading institution it is today." - Edith Heard

ALT "The Francis Crick Institute has quickly established a global reputation for its work at the frontiers of science. I relish the challenge of building on that work. I also want to pay tribute to Sir Paul Nurse, without whom the Francis Crick Institute would not be the world-leading institution it is today." - Edith Heard

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This paper is remarkable showing hope for RNAi based vaccines--no T cells and B cells are needed. Just good old innate immunity lasting at least 90 days. pnas.org/doi/10.1073/pnas.23…

Live-attenuated virus vaccine defective in RNAi suppression induces rapid protection in neonatal...

Global control of infectious diseases depends on the continuous development and deployment of diverse vaccination strategies. Currently available l...

pnas.org
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Excellent talk by @Alexis_Barr @Official_BSCB Congrats on your award!!
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When things get tense… Carlos Pardo Pastor getting post doc award @Official_BSCB
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Saranne Mitchell knocking it out of the park. Talking about energy and extrusion for her Raff Award @Official_BSCB
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After ~12 years of hard labor, lots of push back and excitement, we are pleased to present our paper showing a new mechanism for the many features of asthma that came out in Science today with an awesome review by Jeffrey Drazen and Jeffrey Fredberg.science.org/doi/10.1126/scie…

Bronchoconstriction damages airway epithelia by crowding-induced excess cell extrusion

Asthma is deemed an inflammatory disease, yet the defining diagnostic feature is mechanical bronchoconstriction. We previously discovered a conserved process called cell extrusion that drives...

science.org
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The review: science.org/doi/10.1126/scie…

Epithelial cells crowded out in asthma

Bronchoconstriction causes epithelial cell extrusion that promotes airway inflammation

science.org
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We can prevent this destruction using inhibitors of extrusion--especially gadolinium. We hope that this will not only prevent the acute features of asthma but also calm down airway damage and inflammatory cycle that promote further attacks.
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