@RohmMaria

Group leader @HelmholtzMunich @helmholtz_diabc @ERC_Research studying metabolism, energy homeostasis, cachexia

 Munich, Germany
Joined October 2020
  • Tweets313
  • Following287
  • Followers700
24Media
👏👏👏 Check out this very cool story on a Tumor secreted protein causing cachexia by altering TGF signaling, by my colleague and friend @BerrielDiaz and led by amazing postdoc @JulianoMacha17. Happy I could contribute a tiny bit 💞
Helmholtz Diabetes Center (HDC)@helmholtz_diabc
Sep 1
🚨 New publication in Cancer Discovery! Our study identifies ADAMTSL4 as a previously unknown driver of #CancerCachexia and a promising therapeutic target. Congratulations to Juliano Machado, Stephan Herzig, Mauricio Berriel Diaz & all collaborators! 🔗t1p.de/4wzzc
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Heute in @zeitonline ein Artikel zur @HyperMet Forschungsgruppe. Bimagrumab-Studien bestätigen, dass die Stimulation von Muskelhypertrophie anti-Adipositas und anti-Diabetes-Effekte hat, die fast genauso stark sind wie die, die mit der Abnehmspritze (GLP1-RAs) erreicht werden.
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#Throwback REVIEW | @BerrielDiaz, @RohmMaria, S Herzig Cancer cachexia: multilevel metabolic dysfunction nature.com/articles/s42255-0…

Cancer cachexia: multilevel metabolic dysfunction

Nature Metabolism - In this Review, the authors highlight cancer cachexia as a complex and multifactorial disorder, and discuss the underlying host-driven and tumour-driven metabolic changes,...

nature.com
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Really looking forward to this meeting on #cachexia in Vienna!
Felix C Richter@CleeteRichter
Jul 25
Replying to @CleeteRichter
Now, we plan the first Vi-CaN symposium with leading cachexia researcher joining the discussion including Vickie Baracos @UAlberta, Eduardo Bruera @UTMDAnderson, @RohmMaria @HelmholtzMunich and @realTonyHui @HarvardChanSPH. Sign up today: meduniwien.ac.at/web/vienna-…

Vi-CaN Symposium 2026 | MedUni Wien

meduniwien.ac.at
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Now, we plan the first Vi-CaN symposium with leading cachexia researcher joining the discussion including Vickie Baracos @UAlberta, Eduardo Bruera @UTMDAnderson, @RohmMaria @HelmholtzMunich and @realTonyHui @HarvardChanSPH. Sign up today: meduniwien.ac.at/web/vienna-…

Vi-CaN Symposium 2026 | MedUni Wien

meduniwien.ac.at
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Join the DGMet & HyperMet Exercise Metabolomics Symposium! 🗓️ 6 Aug 2026 | ⏰ 16:00–18:00 CEST 🎤 Cora Weigert, Dirk Weber & Tim Havers Topics: exercise metabolomics, N-acetylated amino acids & oral protein tolerance test. Everyone welcome! 🔗 teams.microsoft.com/meet/317…
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💫 I'm excited to share our new Comment @NatureRevEndo, calling to reframe #cancercachexia from malnutrition to treatable metabolic disease: nature.com/articles/s41574-0…
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more replies
Emerging evidence shows that cachexia is a systemic metabolic disease - one that deserves earlier recognition, better monitoring and targeted interventions. Reframing cachexia in this way could help improve quality of life, treatment tolerance and, ultimately, patient outcomes.
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😍 We'd love to hear your thoughts. How can we better integrate cachexia into routine cancer care and precision oncology? @NaturePortfolio @ERC_Research @helmholtz_de @HelmholtzMunich @helmholtz_diabc @DiabResearch @JoseMGa95491291
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🚨 Abstract submission closes TOMORROW! Don't miss your chance to present your research at the 13th Helmholtz Diabetes Conference in Munich. 📅 September 21–23 ➡️ "Diabetes Across the Lifespan" 📌 Flash Talks • Poster Sessions • Awards 🔗 Submit now: t1p.de/zegxf
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25th HyperMet talk by Roberta Sartori this Thursday 15 h Munich time. Join here: teams.microsoft.com/meet/355… Passcode: h2Vp3fi9
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#Throwback REVIEW | @BerrielDiaz, @RohmMaria, S Herzig Cancer cachexia: multilevel metabolic dysfunction nature.com/articles/s42255-0…

Cancer cachexia: multilevel metabolic dysfunction

Nature Metabolism - In this Review, the authors highlight cancer cachexia as a complex and multifactorial disorder, and discuss the underlying host-driven and tumour-driven metabolic changes,...

nature.com
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ICYMI: What drives metabolic dysfunction and body wasting in cancer #cachexia? doi.org/10.1172/JCI194687 Here, Pauline Morigny @MorignyPauline Maria Rohm @RohmMaria & team @HelmholtzMunich find high circulating ceramides define cancer cachexia in mice and patients. And targeting ceramide synthesis counteracts mitochondrial dysfunction, impaired energy homeostasis, and muscle atrophy in cachectic mice. The image: In primary hepatocytes, ceramides interfere with mitochondrial branching and junctions, inducing cachexia-like phenotypes. #Metabolism #Ceramide
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Thank you for highlighting our study @PerrimonLab @MarcusDGon 🙏
Journal of Clinical Investigation
@jclinicalinvest
May 29
Liver-derived ceramides link metabolism to tissue wasting in cancer cachexia: doi.org/10.1172/JCI206031 Norbert Perrimon, Kerui Huang @perrimonlab, Marcus D. Goncalves @marcusdgon @nyugrossman provide a Commentary on Morigny et al.: doi.org/10.1172/JCI194687 @MorignyPauline @RohmMaria #Cachexia #Metabolism #Ceramide
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Happy to share our latest paper showing that liver-derived #ceramides drive #muscle dysfunction in #cancer #cachexia . Study led by @MorignyPauline at @helmholtz_diabc
Pauline Morigny@MorignyPauline
May 15
Replying to @MorignyPauline
I hope you’ll enjoy reading it ! Link to the paper below 👇 jci.org/articles/view/194687 Associated comment 👇 jci.org/articles/view/206031
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Amazing collaboration partners!! @BerrielDiaz @Laure_Bindels @ZeigererLab @OndrejKuda @Dorie00 @DrOlgaMunich and many more. Thank you 🙏
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We show that blocking ceramide synthesis systemically or liver-specifically improves mitochondrial function in liver and muscle, counteracting muscle wasting.
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Visit the interactive booth of our Research School at the Pop-Up Exhibition this weekend! 🙌 📅 May 15–17, 09:00–17:00 📍@DeutschesMuseum “Diabetes Uncovered” – explore #DiabetesResearch through hands-on experiences, games, and fascinating insights. 🔗 t1p.de/2lmt9
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📢The 𝗽𝗿𝗼𝗴𝗿𝗮𝗺 for the 13th Helmholtz Diabetes Conference on "Diabetes Across the Lifespan" is now online! 🔍Explore sessions, speakers, and topics: helmholtz-munich.de/en/diabe… 🗓️Registration and abstract submission open next week - stay tuned! 🙌#HelmholtzDiabetes2026
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