Group Leader @UmeaUniversity & Wallenberg Fellow @WCMM_UmU. Postdoc @EMBL; PhD @CNIOStopCancer. Long-range gene regulation & 3D-chromatin organization in cancer
Umeå, Sverige
Joined March 2020
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... and now it's real! 🤗 Out now @NatureComms!! Incredibly happy to see this work published and very proud of my team! #Enhancer #3Dgenome #Glioblastoma #CancerNeuroscience
nature.com/articles/s41467-0…
The PALS Summer School in Omis is back!
Register now for the 2026 edition 👇
Registration for the PALS Summer School in Transcriptomics is Open 🧬 23-26 June 2026 trippus.net/summerschool2026
Join us in this wonderful place 🇸🇪 to learn
Theory & Computation from Famous Scientists in the Field
w @Remeseiro_Lab
Support by @scilifelab & @KAWstiftelsen
3D genome & Cancer 👇
Last reminder: We’ll see you bright and early at 9:30 AM EST on the 25th to kick off #chromatin2025! Fantastic lineup of speakers with discussion to follow each talk. Don’t forget to register for this virtual meeting if you haven’t yet: bit.ly/chromatin-2025
@remeseiro-lab.bsky.social retweeted
The Brain Prize 2025 #webinars uncover how the nervous system drives and responds to cancer - from brain tumours to neural circuit remodeling and cancers outside the brain.
brainprize.org/winners/cance…
#CancerResearch #Neuroscience #TheBrainPrize
✨ Excited to share I’ve received a @ssmfgrants #Consolidator grant!
📣 Recruiting a #postdoc to study #cancer #neuroscience #3Dgenomics #multiomics #singlecellomics
🔬How neural inputs shape #3Dgenome and #cellplasticity in #glioblastoma #GBM
Apply 👇
rb.gy/m7xz7b
Apply and join my lab at @umeauniversity 🇸🇪 and @WCMM_UmU , generously funded by @ssmfgrants #Consolidator, @Vetenskapsradet @Cancerfonden @KAWstiftelsen
#GABAergic neuron-to-glioma synapses were recently found in #DMG/#DIPG, but not #GB @michelle_monje
@TaraBarronPhD
Yet our ML-based analysis flagged #GABA signalling as key in #GB. Notably, we showed that #GABAergic neurons promote #GB cell proliferation in co-culture assays.
With these studies we have showed that #epigenetic regulators of the #neuron-to-glioma axis can serve as actionable #targets in #GB.
Viewing neuron-glioma interactions through an epigenetic lens helped us understand how glioma cells exploit neural signals to fuel their growth.
📣 New pre-print from the lab: 👉 “Gene regulatory networks linked to GABA signalling emerge as relevant for glioblastoma pathogenesis” #Glioblastoma #GB #GRNs #multiomics #GABA #CancerNeuroscience #ML #GBM
📝 Read the #BioRxiv here:
doi.org/10.1101/2025.04.30.6…
#glutamatergic neuron-to-glioma synapses were found in #glioblastoma — key findings from @Winkler_Lab
@michelle_monje
We showed the SMAD3-PITX1 GRN drives this crosstalk. SMAD3 inhibition + neural activity boosts #GB growth in co-culture with glutamatergic neurons and in vivo.
Among the new #GRNs that we identified, #GABA signalling emerges as a previously unrecognised player in #glioblastoma.
Now we applied #MOBILE, a #ML based method, to integrate #multiomics data from #GB and uncovered new #GRNs and #TFs relevant for #glioblastoma pathogenesis.
📝 doi.org/10.1101/2025.04.30.6…
Over a year ago in @natcomms we showed how rewiring of #enhancer landscape & #3Dgenome underlies #neuron2glioma synaptic communication in #GB. SMAD3 & PITX1 emerged as key #TF and targeting them alters tumour growth.
doi.org/10.1038/s41467-023-4…
📢 New pre-print:
“Gene regulatory networks linked to GABA signalling emerge as relevant for glioblastoma pathogenesis” #Glioblastoma #GB #GRNs #multiomics #GABA #CancerNeuroscience #ML
BioRxiv: doi.org/10.1101/2025...
🦋 Read a full thread here:
bsky.app/profile/remeseiro-l…
👇about our work!
Unlocking the secrets of glioblastoma! Dr Silvia Remeseiro maps the epigenetic landscape of this aggressive brain cancer, paving the way for new treatments. doi.org/10.1038/s41467-023-4… Read more: scientia.global/dr-silvia-re… @Remeseiro_Lab
Looking for a #GroupLeader tenure-track position?
👇 Check-out and don't miss this opportunity to start your research group with really good funding!
umu.se/en/work-with-us/open-…
@WCMM_UmU @umeauniversity
@remeseiro-lab.bsky.social retweeted
Today’s the day! 🎉 We’re kicking off #chromatin2024 at 9:30 AM EST w/ @mitchguttman, @Gerlich_Lab, @G_Stik, @MariekeOudelaar, @Yael_David, @_AnthonySchmitt & other great speakers! If you haven’t registered yet, there’s still time: bit.ly/chromatin-2024. See you soon!
