@R_Labruere

PhD Bioorganic chemistry / HDR👨‍🎓- Smart molecules - "Cycl'in-cell" Prodrugs - Ecodrugs - Spontaneous Reactions👨‍🔬

 Essonne, Ile-de-France
icmmo.u-psud.fr/Labos/LCBB/cv/labruere.php
Joined October 2013
  • Tweets68
  • Following236
  • Followers133
3Media
Raphaël Labruère retweeted
Gustave Roussy
@GustaveRoussy31 Jan 2023
#Vivant | Touchés par un cancer, ils témoignent. Découvrez l’histoire de Virginie, diagnostiquée d’un #cancerdupoumon métastasé et qui en 2016 intégra un essai thérapeutique à @GustaveRoussy, un dernier espoir qui se révélera être une délivrance dans son parcours de #guérison.
2
13
50
6,319
Raphaël Labruère retweeted
Science Magazine
@ScienceMagazine2 Jan 2023
Humans consume more pharmaceuticals than ever, leading to increased pharmaceutical pollution of global ecosystems. New measures and research are needed to limit these chemicals’ largely unexplored ecological impacts, argues this #SciencePerspective. scim.ag/12r
8
115
7
309
96,664
Photoinduced Oxidation of Benzylic Boronic Esters to Ketones/Aldehydes via α-Borylalkyl radicals (@OrgChemFront): pubs.rsc.org/en/content/arti….
6
37
Raphaël Labruère retweeted
nature
@Nature31 Aug 2022
Research briefing: Engineered yeast brews precursors of anticancer drug vinblastine nature.com/articles/d41586-0…
2
20
2
70
Raphaël Labruère retweeted
Angewandte Chemie@angew_chem24 Aug 2022
A Carbon-Carbon Bond Cleavage-Based Prodrug Activation Strategy Applied to beta-Lapachone for Cancer-Specific Targeting (Zhang) onlinelibrary.wiley.com/doi/…
2
16
Raphaël Labruère retweeted
BLERIOT LAB@YvesBleriot19 Jul 2022
I am hiring a post-doc fellow for a 12 month period starting in October 2022 on a project that merges carbohydrate and organometallic chemistries. Please RT
1
60
1
75
After 5 yrs of hard work on this @AgenceRecherche project on the development of an ecodrug through retro catabolic drug design approach, the results are now out!🥳 I am grateful to Ecosys lab @AgroParisTech, all coauthors for their work! @UnivParisSaclay tinyurl.com/4xxdx7sd
2
1
4
@mafflos @CharlesSkarbek @stephaniesalzb1 @INC_CNRS
1
Nos travaux d'écoconception du méthotrexate #ICMMO sont mis en lumière @lamethodeFC !! @INRAE_France @UnivParisSaclay
La Science, CQFD@ScienceCQFD23 Mar 2022
[#Podcast] Médicaments : une pollution fleuve bit.ly/3wLCApl à (ré)écouter via @franceculture !
1
3
Raphaël Labruère retweeted
CNRS à Paris-Saclay@CNRSIdFSud25 Nov 2021
#TalentsCNRS La médaille de bronze 2021 est remise à Wadih GHATTAS,chargé de recherche CNRS à l'#ICMMO d'Orsay (@INC_CNRS @UnivParisSaclay). Il est aussi récent lauréat d'un prix de la société chimique de France (@reseauSCF) : new.societechimiquedefrance.…
Wadih Ghattas© Laurent Ardhuin pour le CNRS

ALT Wadih Ghattas© Laurent Ardhuin pour le CNRS

3
4
12
With Dr Turos group @usfchemistry in downtown Tampa!🌞🇺🇸 Thanks to #MERR program @UnivParisSaclay for the opportunity to discuss collaborative research at @USouthFlorida
2
3
Good morning Florida! Good morning USF!
3
Very happy to share our @angew_chem communication on antitumor #prodrugs working by intramolecular cyclization. Congrats to @HichemMaslah @CharlesSkarbek and to our collaborators T. Le Saux and L. Jullien @Chimie__ENS for the hard work. @UnivParisSaclay onlinelibrary.wiley.com/doi/…

In‐Cell Generation of Anticancer Phenanthridine Through Bioorthogonal Cyclization in Antitumor...

An antitumor prodrug platform generating a significant variation in the 3D structure in comparison to the free drug was developed. A totally inactive precursor was shown to produce a cytotoxic...

onlinelibrary.wiley.com
4
7
22
#prodrug #Cancer @HichemMaslah @CharlesSkarbek 👍
This Post is from an account that no longer exists. Learn more
1
3
Raphaël Labruère retweeted
Darryl B McConnell@D_B_McConnell4 Dec 2020
It's important to know the size of the bricks when designing a house. Here's the medchem atoms table from yesterday's KRAS webinar. Iodine is not as big and hydrogen is not as small as most people think. I'll exchange volume with surface area pics when I get a chance.
2
12
4
68
Raphaël Labruère retweeted
Idylle@IdylleLabs3 Dec 2020
#ResearchersNewTools #optogenetics "Once upon a time, a physicist asked a chemist whether he could design a caged inducer to photocontrol protein activity in living organisms" 🌟#ACTIFLASH by Ludovic Jullien, Isabelle Aujard & Thomas Le Saux @Chimie__ENS idylle-labs.com/actiflash-by…
Ludovic Jullien, Isabelle Aujard & Thomas Le Saux from @Chimie__ENS designed #Actiflash

ALT Ludovic Jullien, Isabelle Aujard & Thomas Le Saux from @Chimie__ENS designed #Actiflash

8
1
13
Merci @FondationARC de soutenir nos travaux et de les mettre en lumière !👍
Fondation ARC@FondationARC4 Nov 2020
Promédicaments : retours sur les travaux de @CharlesSkarbek et @R_Labruere, chercheurs de l’Institut de chimie moléculaire et des matériaux d’Orsay, soutenus par la @FondationARC fondation-arc.org/actualites…
1
6
Raphaël Labruère retweeted
Institut Curie@institut_curie10 Oct 2020
#OctobreRose | Comment un #CancerDuSein 🎗️ migre-t-il vers d'autres organes ? 🔎 Décryptage en images du mécanisme métastatique, dont la compréhension est clé pour l'émergence de nouvelles pistes thérapeutiques #ContreLeCancer. ⤵️
12
16
Raphaël Labruère retweeted
Stephen V Liu, MD
@StephenVLiu18 Sep 2020
#ESMO20 Top right shows the IC50 of Tarloxotinib-E in human cell lines, bottom right corroborate with additional mutations in BAF3 models. Note the differential target inhibition for Tarlox-E with a lower IC50 for #HER2 than EGFR and the lowest IC50 for #NRG1 fusions. #LCSM
1
3
8
Our latest Review “Anticancer boron-containing prodrugs responsive to oxidative stress from the tumor microenvironment” has been published in EJMECH doi.org/10.1016/j.ejmech.202…. Congratulations @HichemMaslah @CharlesSkarbek @stephaniesalzb1 !
3
7
Load more