Genetics; Computing; Viruses; RNA | The Laboratory for RNA-Based Lifeforms | Molecular Genetics / Donnelly Centre @ UofT 🇨🇦
Toronto
Joined July 2022
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This is the most consciousness-expanding project I've had the pleasure to contribute to:
🧬 We assembled all 27 million sequencing datasets / 44 petabases, and can search it in hours 🤯 🌎🧬
Next goal: SRA-scale BLAST search in sub 60 seconds
Today we’re excited to freely share an early-version of, perhaps, the world’s most expansive genetics dataset: Logan.
#bioinformatics #petabase #genetics #genomics #openscience
biorxiv.org/content/10.1101/…
Artem Babaian retweeted
📣 Applications are open for the CIFAR Global Scholars program!
Develop and lead highly interdisciplinary research, expand your network and gain valuable leadership training.
🔗 Learn more and apply by November 4: cifar.ca/next-generation/glo…
Artem Babaian retweeted
Spanning eight years and over 4,800 experiments, a Hughes Lab global collaboration has concluded with the creation of the Codebook: an enormous database that has illuminated how transcription factors influence human gene regulation:
thedonnellycentre.utoronto.c…
Artem Babaian retweeted
A history of viral encephalitis is one of the strongest risk factors for developing dementia. With @JacobJacobog02, Yifan Chen, @RNA_Life, and @RyanDhindsa, we refine this link by describing a neuronal cell type that can reactivate HSV-1 in humans 1/n
biorxiv.org/content/10.64898…
ALT https://www.biorxiv.org/content/10.64898/2026.04.29.721769v1
🧬Ultra fast petabase-scale virus discovery is here! 🚀
In our lab’s newest preprint, Jess explores the biodiversity of Papillomaviruses (PVs) in record time
🧵1/5 👇
🔗: doi.org/10.64898/2026
🧵4/5 Analyzing this as an 'in-silico ecosystem', we find PV biodiversity hotspots in East Africa and South America, and show that undersampl biomes like Tropical Forests or Mangroves disproportionately yield viral diversity.
🧬5/5 #Genomics is our shared evolutionary heritage. We re-imagine public sequencing data not as an archive, but a living digital twin of Earth’s Genome.
Infrastructure like 🗻Logan🗻 will help unlock this frontier of genetic diversity 🌎🧬
Preprint🔗: doi.org/10.64898/2026.04.21.…
Molecular Genetics @ University of Toronto 🇨🇦@UofT🦠 is recruiting an Assistant Professor in #Virology!!
Come build your dream lab!
🔗jobs.utoronto.ca/job/Toronto…
Artem Babaian retweeted
We are looking for a postdoctoral fellow to work on induced proximity and functional genomics! Join our team in Toronto 🇨🇦 to tackle major challenges in oncology and neurodegeneration.
nature.com/naturecareers/job…
Artem Babaian retweeted
#UofT launches $24-million program to create 100 new postdoctoral positions, accelerate independent research ➡️ uoft.me/bZI
ALT An aerial view of King's College Cirlce
Artem Babaian retweeted
Turn your #PostDoc into a Global Impact. 🌍 Join @UofT/#RNAlab to evolve plastic-degrading enzymes #SynBio. 🧬🔬
SYNTHETIC + MOLECULAR BIOLOGY on MICROPLASTICS - POSTDOCTORAL FELLOW @RNA_Life
University of Toronto
See the full job description on jobRxiv: jobrxiv.org/job/university-o…
#enzymology #microplastics #moleculargenetics #syntheticbiology #Yeastgenetics
#ScienceJobs
jobrxiv.org/job/university-o…
MetaGraph: A Landmark paper in Petabase-scale Genomics is _finally_ out!
🚀🚀 Congrats Andre + Co. making the world's sequencing data🧬 available in a major achievement for the field. 🚀🚀
After years of research and continuous refinement, we’re thrilled to share that our paper on the MetaGraph framework — enabling Petabase-scale search across sequencing data — has been published today in Nature (nature.com/articles/s41586-0…).
Artem Babaian retweeted
After years of research and continuous refinement, we’re thrilled to share that our paper on the MetaGraph framework — enabling Petabase-scale search across sequencing data — has been published today in Nature (nature.com/articles/s41586-0…).
Artem Babaian retweeted
Now online, our work in nucleorhabdoviruses
our latest manuscript with
@humbertodebat
and Ralf Dietzgen is just out in Virology! We identified 47 novel nucleorhabdoviruses in our final chapter of a trilogy exploring the hidden diversity of plant-associated rhabdoviruses sciencedirect.com/science/ar…
Artem Babaian retweeted
A warm welcome to Donnelly's newest Faculty member, Dr. Khalid Al-Zahrani! Our next news story will talk about his research and his journey; from elementary school trips to Canada Science and Technology Museum, to the first time he did bench work.
Artem Babaian retweeted
Have you ever wanted to peek behind the curtain of a hackathon? Our most recent article covers everything, from the creation of the winning projects to the private judging deliberations.
Read it here: thedonnellycentre.utoronto.c…
Artem Babaian retweeted
One year after our initial preprint, we're excited to post a major update to Logan.
At its heart, Logan is the assembly of 27 million samples (50 Pbp) using a 6-day cloud-compute peaking at 2.2M vCPUs. This compresses the SRA 140x compared to raw FASTQs.
github.com/IndexThePlanet/Lo…
Artem Babaian retweeted
🌎👩🔬 For 15+ years biology has accumulated petabytes (million gigabytes) of🧬DNA sequencing data🧬 from the far reaches of our planet.🦠🍄🌵
Logan now democratizes efficient access to the world’s most comprehensive genetics dataset. Free and open.
doi.org/10.1101/2024.07.30.6…
🤯 One of the coolest stories I've ever come across showcasing virus-host-superhost interactions. This is a major paradigm in virus pathology that is woefully under-explored. 🍄 #virology #microbiology #fungi
🚨 Fungi + viruses + mammalian lungs? Buckle up! Our new paper in
@natmicrobiol.nature.com
uncovers the story of a deadly fungus and its gnarly viral hitchhiker — and how this duo may change how we diagnose & treat fungal disease 🍄🫁🚨 doi.org/10.1038/s41564-025-0… ⬇️
