Paediatric Nephrologist/ Director of the Wellcome Centre for Cell-Matrix Research/ Runner/ Cyclist/ Manchester UK/: views are my own.

Manchester, England
Joined March 2012
Rachel Lennon retweeted
In their Cell Science at a Glance article, Rachel Lennon @RLWczyk and David Sherwood review basement membrane composition, formation and function, and discuss how BMs change in health and disease. journals.biologists.com/jcs/… #OpenAccess
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Rachel Lennon retweeted
#whyscience Day36 This one slide from David Altshuler at the @the_asci @JointMeeting says everything. It shows the extraordinary increase in life expectancy for people with cystic fibrosis over the past few decades. Here’s what science—and academic research—can do.
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ERCSG Recap: Day2 (Friday) of the ERCSG meeting was packed with a remarkable series of high-caliber talks! 🌟 🧪 Prof. @PuellesVictor on tubules and cystic kidneys 🧬 Prof. Rachel Lennon @RLWczyk (I absolutely love her talks!) on podocytes, Alport syndrome, and podocyte biology 💡 Prof. Dr. @Tobias_B_Huber delivered an exceptional lecture — as always, outstanding! 🏥 Prof. Miriam Banas from Regensburg also gave a fantastic presentation! I had the great pleasure of being the final keynote speaker, sharing insights on PEMP, podocytes, and diagnostics of Uniklinikum Greifswald & @NIPOKA_Podocyte . The evening was rounded off with a fantastic dinner and great conversations, which continued later at the bar – a perfect opportunity to make and strengthen contacts! 😃
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Rachel Lennon retweeted
Living with Alport Syndrome can be tough, but you’re never alone. 💜 Whether you need advice, support, or just a chat, Susie, Hannah & the team are here to help! 📧 [email protected] – Reach out anytime! Together, we build a brighter future 💙 #alportuk #alportsyndrome
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The glomerular circadian clock temporally regulates basement membrane dynamics and the podocyte glucocorticoid response doi.org/10.1016/j.kint.2024.… #OpenAccess #glucocorticoids #podocytes @OfficialUoM @galib_ewu36 #kidneydisease #circadianrhythm
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Rachel Lennon retweeted
We'll always have matrix... Happy holidays to all our members and collaborators
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Rachel Lennon retweeted
Reminder! Special issue on #BasementMembranes, biology and pathology at our society journal Matrix Biology, guest editors #PeterYurchenko @stramerlab from @KingsCollegeLon @yoshihiro0604 from @UCSFGouldLab - submit your paper today! For more info👇🏻 sciencedirect.com/special-is…$
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Rachel Lennon retweeted
So pleased to share the first study from our @CRUK @MCRCnews RadNet collab led by the amazing @NabinaPun98 with @TravislabUoM and Prof. Illidge @UCytlak @CRGGlasgow @LydiaBeckerIII @wtccmr biorxiv.org/content/10.1101/…
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Rachel Lennon retweeted
We are looking for a research technician to work on an exciting collaborative project with @RLWczyk using a combination of fly and mammalian models to understand basement membrane physiology during development and disease. jobs.ac.uk/job/DKN082/techni…
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Rachel Lennon retweeted
Today, we celebrate the innovative and impactful work being done in @FBMH_UoM! A special shoutout to Joan Chang for their dedication to supporting and celebrating postdocs—not only in Manchester but across the UK! 👏 Thank you, Joan, for all that you do! #PostdocAppreciation #ResearchExcellence
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Replying to @ASNKidney
@ASNKidney News: Excellent presentation of our results by Dr. Daniel Gale (UK) during the Late Breaking News Session yesterday at @ASNKidney, showing the results of treating 3 Alport syndrome patients with a small molecule from @eloxx_pharma. My company, @NIPOKA_Podocyte, was able to quantify the beneficial effect of the treatment using PEMP analysis. PEMP indicates the improvement of the foot processes of podocytes 🐙, which are essential for the size-selective filtration of the kidney. In addition, @NIPOKA_Podocyte has analyzed biopsies for certain collagen IV chains. The results are amazing with a great potential for treatment of patients! Many thanks🙏 for the excellent collaboration with Dr. Daniel Gale, Sumit Aggarwal @eloxx_pharma, Dr. Rachel Lennon @RLWczyk, @Evotec and many others! *PEMP: Podocyte Exact Morphology Measurement Procedure (patented)
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👏 out now @NatRevNeph from us @ClinGenResource Kidney CDWG! @AndrewMallett8 @AliciaBByrne @RLWczyk @kidneyomicsamps Gene-disease relationships in the #genomics era rdcu.be/dXUt9 👀 this space: outputs from our #expert groups coming soon! nature.com/articles/s41581-0…
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How do we know define gene-disease relationships in nephrology? Here’s a key guide from the @ClinGenResource Kidney Clinical Domain WG in @NatRevNeph!! Amazing to see this out along with the fantastic @ZornitzaS @AliciaBByrne @kidneyomicsamps @RLWczyk rdcu.be/dXUt9
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Genetic kidney disease is an important cause of persistent microscopic hematuria in children & young people. Read this Original Article on frequency of variants in the Alport syndrome genes in individuals under 18 yrs w/microscopic hematuria. #OpenAccess link.springer.com/article/10…
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Missed the PARASOL Scientific Workshop? Learn about the findings on FSGS endpoints @ASNKidney #KidneyWk from @LauraMarianiMD, @DannyGale_1, Abigail Smith, Aliza Thompson, Josh Tarnoff and @NewKidneysOTB. Session Friday, poster Saturday eu1.hubs.ly/H0d6WtH0
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We at @wellcometrust have joined many UK science organisations in signing a letter to the chancellor ahead of the budget at the end of the month. It is crucial that the UK has stable, predictable investment in R&D, not wasteful stop-start funding. ft.com/content/fc00e578-f45c… via @ft
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Rachel Lennon retweeted
1/2 Big news 🗞️ Last year we asked you if you thought it was important for NHS England to include Alport genes in a newborn screening project. The study will test 100,000 newborns for rare genetic conditions which early diagnosis and treatment can make a difference for.
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Rachel Lennon retweeted
TheRuggieroLab@TheRuggieroLab28 Sep 2024
Wrapping up the MBE2024 meeting with the torch pass to Johanna Myllyharju, University of Oulu. A moment illustrated by this great photo montage created by Julia Etich👇🏼 @Matrixbiologie - Get ready for MBE2026 in Oulu, the fifth biggest city of Finland (dixit @ValerioIzzi)😉!
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Rachel Lennon retweeted
Some very cool molecular timer tools to look at #CollagenIV turnover during drosophila development by @stramerlab #MBE2024
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