Stage 2. RCT of conventional RARP vs molecularly-targeted intraoperative fluorescence. Trials unit @SITU_Oxford. Funder @CR_UK. CI @lambalastair. @NDSurgicalSci
Oxford, England
Joined June 2022
- Tweets66
- Following42
- Followers44
- Likes109
Pinned Tweet
Excited to publish our #FirstInMan phase 1 study using IR800-IAB2M (near infrared #PSMA minibody) dosing and toxicity in n=23 men undergoing #RARP +/- #ePLND
#ProstateCancer #PrecisionSurgery
@NDSurgicalSci @LambAlastair
@LabBryant
link.springer.com/article/10…
The ProMOTE Study retweeted
If you're not here come now!!
eUro2, 1715-1800
@gu_onc "From Studio to Stage!!"
With @declangmurphy
& @RenuEapen
#EAU26 @Uroweb
The ProMOTE Study retweeted
Pleased to publish #CostEffectiveness data #LATPvsTRUS in @EurUrolFocus
THM:
•average cost TRUS=£917; LATP=£1062 (∵ device cost/takes longer)
•#LATP not cost-effective (QALY)
But...
•only 4m f/u so doesnt account for ⬆️ PCa diag
#TRANSLATE_Trial
eu-focus.europeanurology.com…
The ProMOTE Study retweeted
Fascinating on UK #PCaScreening
•Men 50-69 yo ❌️ (n=8.2M)
•Familial risk ❌️ (1M)
•Black ethnicity ❌️ (0.37M)
•BRCA mutated ✅️ (21k)
So...the screening gates opened for 1st time! 💥
Thoughtful from #NSC (but suspect many will be disappointed)
bbc.co.uk/news/live/clykgr94…
The ProMOTE Study retweeted
Final case of the day (and of #ERUS25 @GuysUrology) with @bernardorocco73
#RARP modified anterior approach with @Medtronic #HUGO.
65 yo gent looking forward to retirement in Caribbean!
•GG3 8mm Rt ant, GG2 4mm Lt post
•T2N0M0
•ElIPSE trial - rndmed to no LND @BAUSurology
The ProMOTE Study retweeted
Final morning of #ERUS25, the sun is shining in anticipation of the first case of the day with @agalfano at @GuysUrology
Plan is for a @Medtronic #HUGO #rsRARP
Delightful portuguese gent with:
•GG2 6mm Rt anterior
•Borderline cT3a
•MUL 15mm
And fully aware of #LiveSurgery
The ProMOTE Study retweeted
First live case of #ERUS25 ready to rock @GuysUrology. @prokarurol in the #HUGO hot-seat. WHO time-out done. Patient from @GibraltarGov #StBernardsHospital & fully on board with #LiveSurgery concept
#CuttingEdgeSurgery
#EveryDaysALearningDay
The ProMOTE Study retweeted
Co-Chief Investigator @LabBryant outlines #TRANSLATE_TRIAL journey during @NDSurgicalSci #SurgicalGrandRounds this morning.
@OCTRUctu @SITU_Oxford #SGR
#Oxford_Urology
The ProMOTE Study retweeted
V grateful to @declangmurphy for his excellent, provocative & thoughtful "discussant" response to #TRANSLATE_Trial read-out by @LabBryant
@LambAlastair @NDSurgicalSci
@sashi_kommu @DrBenEddy
@HideYamaUrol @Mattpingchao
Watch it again in full here ⬇️
youtu.be/O4-wKmhza6Y
The ProMOTE Study retweeted
Trial CI @LabBryant delighted to read out #TRANSLATE_Trial results during #GameChanger session @Uroweb #EAU25
Thank you to all our investigators, recruiting sites, funders @NIHRresearch and, most importantly, our 1126 pts!
thelancet.com/journals/lanon…
Trial visual abstract below ⬇️
The ProMOTE Study retweeted
Breaking news pod - TRANSLATE trial just presented at #EAU25 with co-publication @TheLancetOncol @LabBryant @LambAlastair @TranslateTrial. Discussant @declangmurphy Deep dive on GU Cast just released youtu.be/QdWlFy2zrHU?si=rIg0…
The ProMOTE Study retweeted
Excited to announce #TRANSLATE_Trial outcomes will read out at 10am Sun 23rd March in eURO Auditorium 1 #EAU25, Madrid
Synchronous embargoed publication in @TheLancetOncol
#LATPvsTRUS - we'll finally give you the answer
Hope to see you there!
@GUCast @LabBryant @LambAlastair
The ProMOTE Study retweeted
@TranslateTrial results @Uroweb EAU Madrid, 10am Sunday 23/3/25, Green Area eURO Auditorium 1. #LATP v #TRUS prostate biopsy, n=1126; 1ry outcome GGG>=2 cancer detection, 2ry = infection, other complications, cost-effectiveness; @LambAlastair @LabBryant @NDSurgicalSci @OCTRUctu
The ProMOTE Study retweeted
Last list on fellowship with @LambAlastair at @OUHospitals NHS Trust . HUGE thank you to Prof. Alastair Lamb, privilege to learn from you. TY for the invaluable masterclass in robot assisted radical prostatectomy. GRATITUDE to excellent scrub team members too! #SurgicalMentor
The ProMOTE Study retweeted
Today we publish first installment of #PROMOTE_Trial in @EANM_NucMed
#EJNMMI journal
n=23; 48% pT3b; 43% pN1
Node +ve fluoro n=8
Margin +ve fluoro n=10
Optimal dose of IR800-IAB2M PSMA minibody: 5mg iv 10d pre-RARP
@PromoteStudy funded by @CRUKresearch
link.springer.com/article/10…
The ProMOTE Study retweeted
How to convert #RARP & #ProstateBx specimens into #CuttingEdge translational science?
State-of-the-Art Tips&Tricks video on #SpatialTranscriptomics analysis w #VisiumV2
@OxPCaBiol @NDSurgicalSci
Presented by @thineskrishna @ #AUA24
#OrganscaleNodes
youtu.be/_jqTHaKSfxo?si=dVXd…
The ProMOTE Study retweeted
@Freddie_Hamdy drops the 🎤 @Prostate_Forum on thought expmt #FocalTherapy as "4th arm" in #ProtecT_Trial
Opponent: "well never be able to do RCT of Focal vs RP"
FCH: "Here's @PART_Trial, our RCT of partial vs radical Tx, international support & recruiting nicely" !!
#AUA24
The ProMOTE Study retweeted
Please come see our poster showing how we use #SpatialTranscriptomics to deduce clonal metastatic relationships in high-risk surgically treated #prostatecancer
#LethalClone #Space_Study
@QuantumBiobank
@Wien_Yin & @Sandy_Figiel will answer all your qus!
@OxfordCancer #OxSymp24
The ProMOTE Study retweeted
Inviting appls to #Oxford_Urology pelvic uro-onc fellowship for Aug '24.
Approx cases pa 180 RARPs/40 RARCs/600 Bx (TRUS&LATP)
@IntuitiveSurg UK HQ in Oxford
Key role in 4 RCTs:
-@PromoteStudy
-@PART_Trial
-@AtlantaIp2
-FINESSE
Close: 15/12
Intv: 22/12
nhsjobs.com/job/UK/Oxfordshi…
The ProMOTE Study retweeted
A great day of golf ⛳️ @ClubHuntercombe #CaptainsDay in support of @UCAREoxford w particular emphasis on fundraising for @NDSurgicalSci research nurse. Much needed to keep running novel trials/lab research to help our patients
And my awesome sister won Ladies Longest Drive!!🏆🍾 – at Oxford, England
