To the Project ALS Family: We are proud to announce that prosetin, a novel ALS drug candidate developed at the Project ALS Therapeutics Core at Columbia, has been acquired for commercial development by a new company, ProJenX. Read the press release here: prn.to/3JtRymM

It's time for some ALS trivia! 🧠 True or False: Approximately 90% of people diagnosed with ALS have no clear inherited genetic cause. Think you know the answer? Swipe to find out! Want to help move the science forward? Learn more: bit.ly/4zHPhhN

Meet Annelise and Olivia. This November, these sisters will join Team Project ALS at this year’s #NYCMarathon in honor of their father, who lost his life to ALS. 🏃🏻‍♀️💨 Support their marathon fundraising efforts here: bit.ly/4hW25tO

In this blog, Project ALS Executive Director Margot Shanahan shares how 27 women living with ALS are helping advance research inspired by Her ALS Story founder Leah Stavenhagen. Read the blog to learn how Leah's legacy continues to shape ALS research: bit.ly/47k0Kbn ♥️

The Project ALS Therapeutics Core was launched to turn ALS research into therapies and clinical tools. It connects academic labs, industry partners, and the ALS community to advance this mission. Explore how the Core is moving ALS research forward: bit.ly/4dBZUua

Meet our Emerging Leaders Board! We’re proud to introduce the Project ALS Emerging Leaders Board: 11 young professionals bringing new perspectives, energy, and networks to our mission and the fight against ALS. Meet our inaugural members and learn more: projectals.org/emerging-lead…

In 1998, our sister Jenifer was diagnosed with ALS. Her doctor told her to max out her credit cards and go see the world. There was no medicine, and she was given 2–5 years to live. We refused to accept that reality. That determination still drives us today. — Meredith Estess

This week we celebrate DAF Day! This DAF Day, put your giving to work for ALS research. Learn more about donor-advised giving and recommend a grant to Project ALS: projectals.org/dafgiving #DAFDay #DonorAdvisedFund

This holiday season, shop holiday stationery and gifts from Minted and use code FUNDRAISEPROJECTALS to enjoy 20% off your purchase. 🎁 Minted will donate 10% to Project ALS, helping support the research that moves us closer to a future without ALS: bit.ly/4yz5aHw

We ♥️ our Project ALS Family. For more than 25 years our community has helped us find and fund promising research and bring science and bold ideas the support they need to grow. All of our discovery and work is possible because of you. Fuel research here: bit.ly/3W2ViXQ

Fall is officially here, and so is your new favorite layer. 🍂 Make it clear how you feel about ALS while staying warm and dry in our new ALS Hater windbreakers. Shop the new ALS Hater windbreakers here: bit.ly/4rBOMmD

A donor-advised fund is a charitable giving account that lets you set aside funds now and recommend grants to nonprofits you care about over time. By recommending a grant to Project ALS, you can help support the collaborative research moving us closer to a future without ALS.

Meet Riley. This November, she will be taking to the streets of New York City with the rest of #TeamProjectALS at this year’s #NYCMarathon in honor of her grandmother, who lost her battle with #ALS. Cheer Riley on and support her run here: bit.ly/4y9qfry! 📢

The news we have dreamed of is finally here: the Phase 3 FUSION trial for ulefnersen, the treatment that began as jacifusen, met its primary endpoint. This is history-making news for FUS-ALS. Learn more: bit.ly/4zcHKaT

If you could ask an ALS researcher one question, what would it be? Maybe it’s about a clinical trial, a specific gene, why some treatments work for some people and not others, or maybe your question is simply, “What’s taking so long?”

Team Project ALS is officially headed back to the TCS New York City Marathon! 41 incredible runners will take on 26.2 miles through New York City with one shared goal: supporting the research working toward effective treatments and a cure for ALS. #TeamProjectALS #NYCMarathon

Jenifer’s legacy lives on in every step we take toward a future without ALS. We will not stop pushing the science forward and fighting this disease until there are effective treatments and a cure. Donate to support ALS research: projectals.org/?form=donate

The Project ALS Therapeutics Core is studying protein toxicity—the protein clumps that form in neurons not only in #ALS, but all neurodegenerative diseases. What we’re learning about protein toxicity at the Core informs drug discovery across these diseases.

We want to hear from those living with ALS: If you could save one part of yourself from the ravages of ALS, what would it be? This is a safe space for discussion, and there’s no right answer. Share with us in the comments. 🫂

There’s a lot happening in the search for effective treatments and a cure for ALS. Stay in the know with our latest research, Project ALS Therapeutics Core updates, community stories, events, and more. Join our mailing list: bit.ly/3RZOYyV 📩

Just over a week ago, @isaacboots dedicated his Ice Bucket Challenge to Project ALS after the Hamptons got TORCH’D for ALS research! 🧊🔥 Thank you to everyone who broke a sweat and donated to help fund ALS research.