@ProfSimonWad

Professor of Gene Therapy, University College London 🧬🚲🛠

 London, England
orcid.org/0000-0003-4970-4730
Joined August 2011
  • Tweets6.4K
  • Following184
  • Followers1.1K
928Media
Now live - our review of neurodegeneration in lysosomal storage disease - comparing and contrasting disease mechanisms; emerging evidence of unifying convergence bsky.app/profile/profsimonwa… onlinelibrary.wiley.com/doi/…
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Keeping with the new principles of this place where positivity is rewarded: there is a lovely microblogging site hosting my 6th in a series of superwomen in the history of genetics. Rosalind Franklin - prodigious talent bsky.app/profile/profsimonwa… @_BSGCT
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The 6th in a mini-series of posts about the history of women contributing to genetics - some being recognised, others not so much... bsky.app/profile/profsimonwa…
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Check out our translational research to develop a gene therapy for a childhood mitochondrial disease (@Mito_Therapy @Dr_RKarda) bsky.app/profile/profsimonwa…
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Please apply 👇🏼
UCL Institute of Ophthalmology@UCLeye19 Nov 2024
We are looking to appoint a Research Technician to join Professor @MariyaMoosajee's lab, investigating the development of non-viral approaches, using mRNA and non-viral gene therapy, as potential treatment options for RLBP1-retinopathy. Closes 27 Nov: ucl.ac.uk/work-at-ucl/search…

UCL – University College London

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

ucl.ac.uk
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Non-biology photo here. This is the Britannia Hotel in Manchester £50/night- (lecturing at Manchester Metropolitan). Manchester is a beautiful place. @DrNLK0 @drol007 @helencooksley
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Check out our work at #ESGCT2024 : •My poster #P0479 on our patented viral vector GT for metabolic diseases •Ala'a Siam #OR043 •Luke Tappouni #P0510 •Sam Devereaux #P0745 linkedin.com/posts/johncouns…
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Come and work @UCL_IfWH with myself and @Dr_RKarda on a hugely exciting preclinical gene therapy project! Research assistant and postdoc to be hired 🧬👩‍🔬🧑‍🔬
Raj Karda@Dr_RKarda23 Oct 2024
We have a new post-doctoral and research assistant positions open in my team. Pre-clinical gene therapy treatment for a rare neurological disorder. 🧬🧬 Please apply below; ucl.ac.uk/work-at-ucl/search… ucl.ac.uk/work-at-ucl/search… @drelliechilcott @UCL_IfWH @UCLTRO

UCL – University College London

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

ucl.ac.uk
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With ⁦@jerry760⁩ and team at ⁦@dukenus⁩ ⁦@kkh_sg⁩ doing what I do best - frowning while looking down a microscope #iugt #genetherapy ⁦@UCL_IfWH⁩ ⁦@ProfAhadRahim⁩ ⁦@DrGiuliaMassaro⁩ ⁦@Dr_RKarda⁩ ⁦@PrenatalTherapy⁩ ⁦@DrNLK0⁩
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I'm pleased to share that I will be speaking at The Festival of Genomics & Biodata, taking place on the 29th-30th of January 2025 at ExCeL London. Registration is free for over 90% of attendees - register now to join us in January. 
hubs.la/Q02TptWZ0 
#FOG2025
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Simon Waddington retweeted
CavernomaIreland@CavernomaIre9 Oct 2024
👋We have an update for you on the 'Novel Gene Therapy' research. For which Cavernoma Ireland is funding partner alongside Cavernoma Alliance UK & a philanthropist. This is the 1st gene therapy research to be taking place in the UK for hereditary brain cavernoma. @UCL_IfWH
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Simon Waddington retweeted
JulienBaruteau@JBaruteau371719 Oct 2024
To apply: ➡ ucl.ac.uk/work-at-ucl/search…

UCL – University College London

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

ucl.ac.uk
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Simon Waddington retweeted
JulienBaruteau@JBaruteau371719 Oct 2024
The group is expanding! 👇 New exciting post-doctoral researcher position available to study astrocytic GABA metabolism in cortico-subpallial organoids. This project is part of a larger programme assessing links between GABA as gliotransmitter and mental health.
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Simon Waddington retweeted
Raj Karda@Dr_RKarda29 Sep 2024
Our new pre-print paper on “AAV9-mediated targeting of natural antisense transcript as a novel treatment for Dravet Syndrome” is out🧬🧬; biorxiv.org/content/10.1101/… @jantinaod @lifearc1 @GOSHCharity @DravetUK @DSFeu @UCL_IfWH @DNP_ICH @UCLIoN @_BSGCT @UCLTRO

AAV9-mediated targeting of natural antisense transcript as a novel treatment for Dravet Syndrome

Dravet syndrome (DS) is a severe childhood onset developmental and epileptic encephalopathy which leads to life-long disability. Symptoms usually manifest in the first year of life and include...

biorxiv.org
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Simon Waddington retweeted
Juan Antinao Díaz@jantinaod30 Sep 2024
We have a new pre-print paper! “AAV9-mediated targeting of natural antisense transcript as a novel treatment for Dravet Syndrome” biorxiv.org/content/10.1101/… @lifearc1 @GOSHCharity @DravetUK @UCL_IfWH @DNP_ICH @UCLIoN @_BSGCT @UCLTRO

AAV9-mediated targeting of natural antisense transcript as a novel treatment for Dravet Syndrome

Dravet syndrome (DS) is a severe childhood onset developmental and epileptic encephalopathy which leads to life-long disability. Symptoms usually manifest in the first year of life and include...

biorxiv.org
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Simon Waddington retweeted
Helen O'Neill@DrHelenONeill30 Sep 2024
Today we are hosting our Inaugural Reproduction Symposium at @TheCrick and have invited University partners to present the most cutting-edge research in reproduction. Our symposium aims to foster collaboration and research between kindred research groups. #ReproSymp24
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Not sure if it's possible to get a photo like this now, but this was my slightly grainy low-light photo in 1993, when you could still walk up to the stones and there wasn't a visitor centre (or if there was, this was my sports lens...) @drol007 @DrNLK0
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Actually it was probably not a zoom. Or maybe my Pentax 80-200 at 80 - so I could attempt a rule of thirds, with the hazy sun, and the stones. The sun nearly 2/3rds to the right. The top of the stones nearly a 1/3rd up...
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Muscles 💪 and AAV 🦠 - what more could you ask for? Our preprint highlighting strategies for effective transduction of skeletal muscle with AAV with @wenanlan @J_N_Slayer @FrattaLab : biorxiv.org/content/10.1101/… @UCLIoN @UCLBrainScience @UCLDivofSurgery @TheCrick @UKDRI

Refining gene delivery to skeletal muscle with a dual-strategy approach of muscle-tropic AAV...

Viral vector technologies based on adeno-associated virus (AAV) have demonstrated promising ability to deliver genetic cargo to a range of organs in vivo, with several novel candidates showing...

biorxiv.org
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I really wish more people knew about this before they flew off and left us humans alone. It was an alien spaceship posing as a rest stop near the A1.
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