@ProfScottBanta

Professor of Chemical Engineering, Bioengineer, Educator, Mentor, Father

 New York, NY & Fairfield, CT
bantalab.cheme.columbia.edu
Joined July 2022
  • Tweets51
  • Following162
  • Followers330
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Ever wondered if you can genetically alter magnetosome formation in Acidithiobacillus ferrooxidans? doi.org/10.1021/acssynbio.5c…

Overexpression of magA in Acidithiobacillus ferrooxidans Increases Magnetosome Production and...

Abstract. Acidithiobacillus ferrooxidans, a chemolithoautotrophic iron- and sulfur-oxidizing acidophile, is a key contributor to industrial-scale copper me

pubs.acs.org
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Check out our new paper just published in Angewandte in collaboration with Battelle where we used Phage Assisted Continuous Evolution (PACE) to evolve a new peptide for rare earth element (REE) bioseparations. doi.org/10.1002/anie.2025147…

Continuous Evolution of Calmodulin for High‐Purity Separation of Rare Earth Elements

Phage-Assisted Continuous Evolution rapidly transformed a calmodulin fragment into a rare earth element-selective variant capable of single-stage, high-purity separations. The mutations restructured...

onlinelibrary.wiley.com
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Really excited about our new breakthrough in copper metal bioleaching: CRISPR/dCas12a knock-down of Acidithiobacillus ferrooxidans electron transport chain bc1 complexes enables enhanced metal sulfide bioleaching - Journal of Biological Chemistry jbc.org/article/S0021-9258%2…

CRISPR/dCas12a knock-down of Acidithiobacillus ferrooxidans electron transport chain bc1 complexes...

Acidithiobacillus ferrooxidans is an acidophilic chemolithoautotroph that plays an important role in biogeochemical iron and sulfur cycling and is a member of the consortia used in industrial...

jbc.org
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Enzyme Engineering by Force! In new work by Gokulu and Banta in @ACSSynBio we show that DNA springs can be used to stretch open an enzymatic active site to alter substrate specificity. doi.org/10.1021/acssynbio.4c…

Enzyme Engineering by Force: DNA Springs for the Modulation of Biocatalytic Trajectories

Abstract. The engineering of enzymatic activity generally involves alteration of the protein primary sequences, which introduce structural changes that giv

pubs.acs.org
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New #ACSEditorsChoice by Jung at al in @JACS_Au. Engineered protein expressed in bioleaching cells for critical metal ion binding.
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'Overexpression of a Designed Mutant Oxyanion Binding Protein ModA/WtpA in Acidithiobacillus ferrooxidans for the Low pH Recovery of Molybdenum and Rhenium' from @JACS_Au is currently free to read as an #ACSEditorsChoice. 📖 Access the full article: go.acs.org/ajN
Turquoise background image with the journal name, article title, and diagram taken from the TOC

ALT Turquoise background image with the journal name, article title, and diagram taken from the TOC

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Excited to share new work from the Banta lab by Farid Khoury and Zihang Su in @InorgChem where we have characterized a beta roll peptide domain for rare earth element separation - works at low pH! doi.org/10.1021/acs.inorgche…

Rare Earth Element Binding and Recovery by a Beta Roll-Forming RTX Domain

Abstract. The Block V of the RTX domain of the adenylate cyclase protein from Bordetella pertussis is disordered, and upon binding eight calcium ions, it f

pubs.acs.org
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Congratulations to Dr. Ipek Simay Gokulu for successfully defending her thesis "Engineering Enzymatic Modulation Platforms for Biomolecular Applications”. 21st PhD from the Banta Lab!
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Ever thought about the connections between ChemE and food? Chris Chen at @CUSEAS and his collaborators talk about a cool hands-on, food-inspired lab in the latest issue of CEE, part of our @ChESS_2022 Special Issue! Get it ahead-of-print at journals.flvc.org/cee/index
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Please join us for wine and dessert at 8pm on Monday evening in the Plaza International Ballroom F in the Hyatt at #AIChEAnnual !
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New work in collaboration with Castaldi Lab @CCNYChemicalEng describes the engineering of biomining bacteria to bind and sequester copper from waste materials. doi.org/10.1021/acsestengg.3…

Overexpression of AcoP in Acidithiobacillus ferrooxidans for Enhanced Copper Reclamation

Abstract. Copper is an essential critical metal that will be indispensable as we work to reduce our dependence on fossil fuel sources and move to electrifi

pubs.acs.org
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New article by @ProfScottBanta ! Embracing Inhibitions: Here we engineered a formate dehydrogenase to use the inhibitor 3-NADP(H) as a functional cofactor academic.oup.com/peds/articl…

Engineering Candida boidinii formate dehydrogenase for activity with the non-canonical cofactor...

Abstract. Oxidoreductases catalyze essential redox reactions, and many require a diffusible cofactor for electron transport, such as NAD(H). Non-canonical

academic.oup.com
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Congratulations to Dr. Salomon Vainstein for successfully defending his thesis "Engineering Formate Dehydrogenase Enzymatic Activity for Non-Canonical Cofactors Through Rational Design”. 20th PhD from the Banta Lab!
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Our fantastic REU students Steven Martinez and Irene Sarro finished up their work this week. Great job and best of luck!
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Banta Lab Group Summer BBQ 2023! Brisket, Ribs, Volleyball, Ping Pong, and Pool time.
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Excited to share our new work by Dr. Emma Willett in @ACSSynBio where we designed a synthetic metabolic pathway for ATP regeneration powered by cheap fuel oxidation doi.org/10.1021/acssynbio.3c…

Synthetic NAD(P)(H) Cycle for ATP Regeneration

Abstract. ATP is the energy currency of the cell and new methods for ATP regeneration will benefit a range of emerging biotechnology applications including

pubs.acs.org
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Post-Doctoral Research Opportunity We are seeking a highly motivated post-doctoral researcher with experience in protein engineering. To apply, please send a curriculum vitae and the names of three references via email to: Dr. Scott Banta, sbanta@columbia.edu.
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Protein enables better lanthanide separations cen.acs.org/analytical-chemi… via @cenmag

Protein enables better lanthanide separations

A newly discovered form of lanmodulin offers a more efficient way to separate rare earth elements.

cen.acs.org
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This protein can do something amazing – read all about it in this terrific N&V by @ProfScottBanta go.nature.com/3C5fjQw
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Post-Doctoral Research Opportunity We are seeking a highly motivated post-doctoral researcher with experience in protein engineering. To apply, please send a curriculum vitae and the names of three references via email to: Dr. Scott Banta, sbanta@columbia.edu.
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