Paediatric oncologist, clinical trials, neuro-oncology, precision medicine.
Sydney
Joined December 2019
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Prof David Ziegler retweeted
Thanks to The @australian for highlighting this research
theaustralian.com.au/health/…
Prof David Ziegler retweeted
Excited to share our latest publication - precision medicine is the right approach for DMG / DIPG!
nature.com/articles/s41467-0…
Excited to share our latest publication - precision medicine is the right approach for DMG / DIPG!
nature.com/articles/s41467-0…
Thanks to The @australian for highlighting this research
theaustralian.com.au/health/…
Prof David Ziegler retweeted
Heading to the #AACR26 Education Session "Small Patients, Big Data: Making Precision Medicine Work in Pediatric Cancer"? Take a look at this study coauthored by speaker David Ziegler. brnw.ch/21x1IAH @ProfDavidZieg
And now actually published in open access :) !!
rdcu.be/fa3nt
Delighted to share our manuscript - the first look at the epi-transcriptome in DMG!
We discovered that RNA methylation is a critical regulator in DMG. nature.com/articles/s41419-0…
Delighted to share our manuscript - the first look at the epi-transcriptome in DMG!
We discovered that RNA methylation is a critical regulator in DMG. nature.com/articles/s41419-0…
Our lab just published a JoVE video article covering PDX models for paediatric brain cancer. Here’s a quick preview!
Link to full video and article: hubs.ly/Q042_QJ40
Prof David Ziegler retweeted
📰 Discover the special issue of #Daily27 for #ChildhoodCancerDay
Read insights from international experts in our two new articles on #childhoodcancerawareness and new advances in the fight against pediatric brain tumors 💛 #EndChildhoodCancer #Oncology #Health #News 👇🧵
Thanks to 27 Daily for allowing me to share some thoughts on World Childhood Cancer Day
🧵'A New Chapter in the Fight Against Childhood Brain Cancer'
🌍 #InternationalChildhoodCancerDay
✍️ David Ziegler, paediatric oncologist at the @KidsCancerInst
🔗 daily27.info/2026/02/15/a-ne…
#EndChildhoodCancer #BrainCancer #Health #News
Very excited about this paper - new way to shut down transcription in DMG - looking now at clinical translation
Inhibitors of the proteins FACT and BET disrupt transcription in #DiffuseMidlineGlioma and extend survival in mice, hinting this combo can suppress hard-to-target epigenetic drivers of this pediatric cancer. @holly_holliday_ @ProfDavidZieg @KidsCancerInst scim.ag/3ZfoysL
Prof David Ziegler retweeted
Congrats to the team for our work - on the cover of Science Translational Medicine! One more step forward to find effective treatments for #DIPG. Thanks to all our funders - See details here:
New in @ScienceTM 🧬 On the cover!
Our work on diffuse midline glioma (#DMG #DIPG), an incurable paediatric brain cancer driven by epigenetic changes. We asked: Can targeting chromatin slow tumour growth?🔗science.org/doi/10.1126/scit…
#ScienceTranslationalMedicineResearch
Congrats to the team for our work - on the cover of Science Translational Medicine! One more step forward to find effective treatments for #DIPG. Thanks to all our funders - See details here:
New in @ScienceTM 🧬 On the cover!
Our work on diffuse midline glioma (#DMG #DIPG), an incurable paediatric brain cancer driven by epigenetic changes. We asked: Can targeting chromatin slow tumour growth?🔗science.org/doi/10.1126/scit…
#ScienceTranslationalMedicineResearch
Prof David Ziegler retweeted
New in @ScienceTM 🧬 On the cover!
Our work on diffuse midline glioma (#DMG #DIPG), an incurable paediatric brain cancer driven by epigenetic changes. We asked: Can targeting chromatin slow tumour growth?🔗science.org/doi/10.1126/scit…
#ScienceTranslationalMedicineResearch
Prof David Ziegler retweeted
Together, these results support dual FACT + BET inhibition as a promising DMG therapy, hitting both tumour-intrinsic vulnerabilities and immune defenses.
@KidsCancerInst @UNSW
Huge thanks to @aaminahkhan_1, @ProfDavidZieg, @maria_tsoli & all collaborators!
Prof David Ziegler retweeted
This work was generously supported by grants from @nhmrc, @cancerNSW, @DIPGCollab, @CureStartsNowAU, @KidsCancerProj, @thekca, We Love You Connie Foundation and Levi’s project
Prof David Ziegler retweeted
Listen to Oprah! Time to book your trip to Australia. #ISPNO2026
instagram.com/reel/DRw5SJ1gG…
Prof David Ziegler retweeted
Registration and abstract submissions now open for ISPNO 2026! ispno2026.org
The world's entire paediatric brain tumour community will be heading Down Under in 2026 - don't miss out!
Prof David Ziegler retweeted
Join us in Sydney for ISPNO 2026! Experience one of the world’s most vibrant cities, where golden beaches, iconic landmarks & rich First Nations culture await. 🌊🌿
📍 Watch: vimeo.com/1126715713
Registrations open: ispno2026.org
#ISPNO2026 #Sydney #SeeAustralia
