@PrecisionNeuro

Laboratory for Precision Neuroimaging @UCSF. PI’s: @rahuldesikan, @leosugrue. We study brain disease using imaging, genetics, health, and behavioral data.

 San Francisco, CA
precisionneuro-radiology.ucsf.edu/
Joined August 2018
  • Tweets11
  • Following67
  • Followers125
Center for Precision Neuroimaging retweeted
UCSF Imaging@UCSFimaging6 Mar 2019
Dr. Rahul Desikan & his team at UCSF @PrecisionNeuro are building a free online genetic platform for #ALS patients to calculate genetic risk. bit.ly/2C3tbMl

Insight: Genetic research may hold promise for ALS, Alzheimer’s

Why haven’t we found a cure for Alzheimer’s and amyotrophic lateral sclerosis? We don’t even know what causes these conditions, and we have no idea how to prevent, stop or treat them. I am a...

sfchronicle.com
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Center for Precision Neuroimaging retweeted
UCSF Fein Memory and Aging Center@UCSFmac25 Feb 2019
Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration. Beyond APOE, polygenic hazard scores in living subjects were associated with amyloid deposition and neurodegeneration in susceptible brain regions. bit.ly/2Nex6dG @rahuldesikan @ADNI3study
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Center for Precision Neuroimaging retweeted
UCSF Imaging@UCSFimaging1 Feb 2019
'Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration' --> New #research from the @PrecisionNeuro team. bit.ly/2BcPj6G
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"...these findings further suggest a nuanced relationship between polygenic risk and markers of amyloid deposition, pathological tau and neurodegeneration"
Rahul Desikan@rahuldesikan29 Jan 2019
new work from my lab on polygenic risk and #Alzheimer's @UCSFimaging @UCSF @UCSFmac academic.oup.com/brain/advan…

Polygenic hazard score, amyloid deposition and Alzheimer’s neurodegeneration

Tan et al. demonstrate that an Alzheimer’s disease polygenic hazard score predicts regional amyloid PET deposition and longitudinal cortical atrophy, and i

academic.oup.com
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Center for Precision Neuroimaging retweeted
Rahul Desikan@rahuldesikan11 Jan 2019
This is my own genetic data run on our tools - looks like I'd benefit from stem cells and oxidative therapies - this is the real potential for #Genomics for #ALS #treatments - we can do this and any #PALS #fightALS
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Center for Precision Neuroimaging retweeted
UCSF Imaging@UCSFimaging3 Jan 2019
'Partitioning the genetic architecture of #ALS.' New results from @PrecisionNeuro via @biorxivpreprint --> bit.ly/2GRDGXX
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Center for Precision Neuroimaging retweeted
Rahul Desikan@rahuldesikan31 Dec 2018
new work from my laboratory
UCSF Fein Memory and Aging Center@UCSFmac31 Dec 2018
CXCR4 involvement in neurodegenerative diseases. Multi-modal findings suggest that abnormal signaling across a ‘network’ of microglial genes may contribute to neurodegeneration. go.nature.com/2V7LWq6 @karchlab @rahuldesikan
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Our new findings suggest that subsets of ALS patients are at elevated genetic risk for FTD, cardiovascular, or immune dysfunction. Developing multiple pathway polygenic scores in this regard would be important for informing therapies.
Rahul Desikan@rahuldesikan24 Dec 2018
unveiling the genes underlying #ALS - we show how #genes can help you find therapies that may work for you: biorxiv.org/content/early/20…
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Ten observations about ALS! Which of these were unknown to you? #ALS
Rahul Desikan@rahuldesikan13 Dec 2018
here are my 10 observations on #ALS:
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Welcome to the official page of the Laboratory for Precision Neuroimaging @UCSF! Led by Drs. Rahul Desikan @rahuldesikan and Leo Sugrue @LeoSugrue. Please follow us for major updates and news from the lab!
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GWAS for dummies
Brian Resnick@B_resnick23 Aug 2018
Hello! I have written an explainer on genome-wide association studies and genetic risk. vox.com/science-and-health/2… Working on this story made me feel like my brain was going to explode.

The fascinating, stunningly complicated new science of genetics

Scientists are trying to predict your future with your genes. But what are the limits?

vox.com
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