@PinesLab

Cell division lab @ICR_London. Headed by Professor Jonathon Pines. Tweets are from anyone in the lab

 London, England
Joined March 2018
  • Tweets188
  • Following173
  • Followers1.2K
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Our second cell culture suite is almost ready for operation. Note the beautiful industrial design ceiling.
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Thanks to Laurène Deshons for overseeing the project.
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Just retweeted the powerful film concerning the criminalising of refugees. I don’t usually tweet political matters but my paternal grandparents fled a civil war and found refuge in the U.K. They wouldn’t today.
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Are you interested in how chromatin regulation affects cell phenotype and drives cancer? We have an open postdoc position in our new group @ICR_London. Join us in central London! jobs.icr.ac.uk/vacancies/544…
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It's official! The Salk Cell Cycle Meeting will start on 24th July. Here's the stunning poster referencing astronomical clocks created by Beata Science Art @beatascienceart. Jan, Silke, Tony and I hope to see you all there!
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Some happy news: Jörg Mansfeld has been awarded a CRUK Senior Cancer Research Fellowship to pursue cell cycle regulation by Reactive Oxygen Species (ROS). Many congratulations, Jörg, on the award of this extremely competitive fellowship!
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Save the date! The Salk Cell Cycle Meeting will take place this July, 24th-27th. More details soon...
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That's it - we can no longer apply for ERC grants. UK Science is currently in a sad place. We are unable to take to take a full part in the European scientific community that we find so welcoming and beneficial.
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We are in the bizarre position that the last set of ERC Grant awardees in the UK have to reject their grant so that the UK Government will pick up the tab...
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Many congratulations to Alex Radzishueskaya in our Division who has been awarded an ERC Starting Grant!
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We are looking for a microscopist to pursue our exciting discoveries with Fluorescence Cross Correlation Spectroscopy (FCCS). jobs.icr.ac.uk/vacancies/392…
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FCCS has already given us unexpected insights into how the APC/C recognises Cyclin B1, and how Cyclin-CDK complexes are assembled. Now we are addressing how the Spindle Assembly Checkpoint works!
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Saptha has been brilliant in optimising FCCS but is moving to a new position (though he'll be able to help get someone started). Join us to elucidate the mysteries of mitosis in living cells.
Excellent talk by Luca at the Consequences of Aneuploidy meeting honouring Angelika Amon @FASEBorg #Aneuploidy22. I think Angelika would have approved.
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Exciting Science for Gideon and his team on how DNA can become its own enemy!
🧬 The Coster Lab 🔬@CosterLab
20 Jul 2022
📢 Hot off the press 📢 🧬 Ever wonder why some DNA sequences are difficult to replicate? Using reconstituted replisomes we revealed that structure-forming repeats induce robust replication stalling and uncovered structure-specific recovery mechanisms: nature.com/articles/s41467-0…
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A ROS-dependent mechanism promotes CDK2 phosphorylation to drive progression through S phase cell.com/developmental-cell/…

A ROS-dependent mechanism promotes CDK2 phosphorylation to drive progression through S phase

Reactive oxygen species (ROS) are by-products of mitochondrial respiration. Kirova et al. find that mitochondrial ROS increase during the cell cycle and oxidize cyclin-dependent kinase 2 (CDK2) to...

cell.com
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Congratulations to Jörg Mansfeld and colleagues on identifying a link between the redox state of a cell and the decision to replicate. Implications for the tumour micro environment and radiation therapy.
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Congratulations to George Poulogiannis @PoulogiannisLab who has been awarded a Future Leaders Fellowship from UKRI! George is at the cutting edge of cancer metabolism research.
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