@PhaseGenomics
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Blueprints for Biology™: Genomics, Metagenomics, Cytogenomics | ProxiMeta™ Metagenome Deconvolution | Proximo™ Genome Scaffolding | Hi-C Kits |
Seattle, WA
Joined October 2014
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Every Phase Genomics Proximo™ or ProxiMeta™ Hi-C kit now comes with PGShield™, our buffer for room-temperature preservation that keeps samples Hi-C-ready for months.
No cold chain. No culturing. Swipe through for more on the power of PGShield.
Tune in to a new on-demand deep dive from @Labroots and Phase Genomics CEO @ivanliachko on how Hi-C metagenomics connects fragmented DNA and reveals relationships among phages, plasmids, and other MGEs in the microbiome.
You’ll find Ivan’s talk here: labroots.com/ms/webinar/link…
Look for Phase Genomics CEO @IvanLiachko at #ISME20 this week. He’ll join a special session exploring the translation of microbiome science into commercial applications.
You’ll find the session, MS25: Microbiome-Based Products, in room 516 on 8/21 starting at 10:30am local time.
Catch us at a conference: @ivanliachko takes the stage at @FutureinReview on 6/1 for a panel called “Gut Feeling: Hacking Your Microbiome”.
Later that week, from 6/4 to 6/7, he’ll be on the ground at ASM Microbe 2026 in DC. Say “hey 👋” and connect for the latest in Hi-C!
Breeding is supposed to narrow diversity. A new hexaploid oat pangenome in @Nature shows that's not the whole story. HiFi + Hi-C across 30+ lines revealed breeders have been adding structural diversity all along.
Jeff Maughan, PhD, breaks it down in the clip below:
The biggest sustainability challenges are rooted in biology we’re still learning to understand. Hi-C helps build better genomes and unravel microbial communities that support healthier soils, stronger crops, and more resilient ecosystems. Happy 🌎 Day from Phase Genomics.
Long reads get you contigs. Proximo™ Hi-C Kits for Plants get you chromosomes you can put to work or meaningful trait / QTL mapping and functional analysis.
Tell us about your research and take 20% off through May 1👇
info.phasegenomics.com/hi-c-…
One oat line has more structural variation than a panel of wheat lines. That finding, from the 1st chromosome-scale oat assembly, led to a 30-line hexaploid oat pangenome published in @Nature using HiFi+Hi-C.
Full breakdown from senior author Jeff Maughan, PhD, in the clip below
Your research budget just got a little more room to grow. Take 20% off Proximo™ Hi-C Kits for plant genomics until May 1st.
Hi-C unlocks chromosome-scale insights from your long reads. Get started here 👇
info.phasegenomics.com/hi-c-…
New in the Journal of Water and Health: ProxiMeta™ Hi-C metagenomics improves antimicrobial resistance tracking in wastewater.
Key findings:
→ 2,816 traits detected
→ 554 genes linked to hosts
→ 52.9% of genes were ARGs
🔗iwaponline.com/jwh/article/2…
Phase Genomics retweeted
From the @MicrobiomeTimes Partnership Forum in Copenhagen with colleagues abound including @evohologen @chuttenh @PhaseGenomics @MortenLimborg @SeventureP. The best of the microbiome science applications is here, Wolbachia included!
32% off ProxiMeta™ Hi-C kits ends 3/15 (then save 16% through end of month).
You’ll get:
✅ High-quality MAGs from complex samples
✅ More complete genomes than traditional binning
✅ Accurate host attribution for phages, plasmids, and AMR genes
👉info.phasegenomics.com/march…
March MAGness is here! Score special pricing on ProxiMeta™ Hi-C kits for metagenomics & microbiome studies in everything from complex soil samples, to gut microbiomes, to bioreactors:
🔬 32% off | March 2–15
🔬 16% off | March 16–31
Get started here 👇
info.phasegenomics.com/march…
FISH finds what it's looking for, and only what it's looking for. In a new study in @AjHematologyshows, Hi-C confirmed FISH findings, plus chromothripsis, CN-LOH & complex rearrangements that FISH probes can’t pinpoint.
🔗onlinelibrary.wiley.com/doi/…
New Nature Plants study using Proximo™ Hi-C shows how a hybrid eelgrass species inherited low-light tolerance genes from its deep-water parent that could change how we approach coastal restoration.
More from Todd Michael, PhD & team at @salkinstitute 📄 nature.com/articles/s41477-0…
New Publication in @PLOSBiology : Optimized Hi-C analysis (Z-score filtering) boosts specificity & reveals virus-host interactions using Phase Genomics’ ProxiMeta™ Hi-C: 79 genus-level matches + 293 new linkages in well-studied, climate-critical soils.
journals.plos.org/plosbiolog…
"A year and a half ago, we couldn't have resolved this hybrid genome."
New tech (long reads + Hi-C) let researchers separate parental haplotypes in eelgrass revealing which genes drive low-light tolerance. Todd Michael (@genomeslab) breaks down how:
Phase Genomics IRL: a few days together in Portland for real-time collab & creativity. Aligning on new products, pressure-testing ideas, a little fun behind the wheel. It’s how we build even better Hi-C tools for the researchers who rely on them.
A few of our favorite moments👇
Tissue prep drives variability early in Hi-C workflows. A new STAR Protocol adds cryogenic tissue grinding before crosslinking, with safe pause points for optimized lab workflows.
See how it improves reproducibility & library quality ⬇️ star-protocols.cell.com/prot…
Phase Genomics retweeted
Combining @PhaseGenomics and @PacBio HiFi allowed acquisition of the complete 🦠genome.
It is composed of 1 chromosome and 2 plasmids, which are mobilome-rich, encoding prophages, an orphan CRISPR array, and complete pathways for many novel and essential cofactors, including heme
