Brian Peters (@Peters_DC) header
Brian Peters (@Peters_DC) profile picture

Policy at @AnthropicAI.

Washington, D.C.
Joined October 2010
Photo by Brian Peters (@Peters_DC)Photo by Brian Peters (@Peters_DC)Photo by Brian Peters (@Peters_DC)Photo by Brian Peters (@Peters_DC)Photo by Brian Peters (@Peters_DC)Photo by Brian Peters (@Peters_DC)Photo by Brian Peters (@Peters_DC)Photo by Brian Peters (@Peters_DC)Photo by Brian Peters (@Peters_DC)Photo by Brian Peters (@Peters_DC)
Brian Peters retweeted
We’re committing a portion of Anthropic’s shares to the Anthropic Public Benefit Fund, a new wholly owned entity dedicated entirely to the public benefit. It will start off with 5% of our shares. For every 50% increase in the company’s value over a set baseline, we can contribute up to an extra 2%, subject to our board’s discretion. In total, this means that roughly 20% of Anthropic’s shares are committed to the public good. Our co-founders have already pledged to donate 80% of their equity, and around half our employees are donating a portion of their equity as part of a donation matching program we’ve run since our founding. In the post below, we share more details about our new fund. anthropic.com/news/public-be…
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Brian Peters retweeted
Today we announced the Claude-led discovery of a molecular machine that we suspect could represent a new gene editing mechanism. Its precise function, biotechnological utility (if any), or level of significance is not yet clear, but at minimum it is work I would have been proud to do as a PhD student. The work was done mostly, though not entirely, by Claude: our life sciences team suggested a broad area of research, Claude read through the literature and a bunch of genome data and discovered something interesting, then Claude proposed experiments to verify the discovery and our team carried them out. It’s easy to dismiss this as a one-off or curiosity, but we’ve repeatedly seen a pattern where AI performance in new intellectual domains goes from weak to superhuman in a matter of a few years. In 2023 models struggled to do math at the level of an average high-school student. In 2024 they started to do well on math competitions for the best high-schoolers in the country, in 2025 they started to solve minor open problems, in early 2026 more significant open problems, and in late 2026 they are beginning to solve the top few open problems in all of mathematics. We believe AI for biology is on a similar exponential trend. The main difference between biology and mathematics, of course, is that math can be done purely theoretically, while biology requires experimentation. Some have used this to draw the conclusion that AI’s utility in biology will be limited. We think this is wrong. As we’ve demonstrated today, humans can collaborate with AI to perform the experiments, validate key results in a few weeks and, if necessary, work with the AI to iterate on what they find. Eventually it may even be possible for Claude itself to safely perform the experiments by autonomously controlling lab equipment, with appropriate safeguards in place, but we aren’t doing that today (our lab is also a BSL1/BSL2 facility that doesn't handle materials dangerous to humans). More broadly, biomedical advancement has many stages — from fundamental biology discoveries, to translational research, to drug discovery, clinical trials, and finally the actual delivery of medicines and health care to patients. We are also interested in these later stages, but even simply accelerating the first stage of fundamental biological discoveries has the potential to speed up and broaden the entire pipeline. Improving our understanding of biology and sharpening biologists’ tools can drive forward all of the later stages, for example by identifying new drug targets, finding new therapeutic modalities, allowing for more precise measurement, and speeding up the experimental loop which itself further accelerates our understanding of biology. This will not in itself speed up clinical trial times, but if it succeeds it could greatly increase the number of promising candidates that go into the pipeline — an increase in throughput even though latency remains. In Machines of Loving Grace, I wrote about AI’s potential to “cure most diseases in 5-10 years” — a goal that sounds impossible, but one I believe is just barely possible if AI is applied to every stage of the pipeline. The first step is showing that AI can first help with, and then drive, biological discoveries. Claude’s discovery is the latest in a line of related prior work that goes back decades, beginning with systems like CRISPR, and continuing with discoveries like the bridge recombinase and VIPR in the past few years. Recently, there has been heightened interest in systems based on reverse transcriptase (RT) enzymes, the enzyme underlying the system Claude identified. And most recently, a Stanford team working independently described a novel RT system with an associated non-coding array that is in some ways similar to the one Claude found, though they are distinct systems that evolved independently from each other. I believe that we’re at the very beginning of finding such systems and developing them into powerful tools for biotechnology. I’m proud of the resources Anthropic has invested in accelerating the public benefits of AI through the life sciences, and we’re aiming both to grow our life sciences team and to work with other scientists to extend this approach to a broad range of problems. If you have a proposal for a research collaboration or are interested in joining our life sciences team, please reach out.
Claude has discovered a previously unknown enzyme system hidden in the DNA of bacteriophages. Beside the enzyme’s gene sits a long array of repeating DNA—a structure that looks somewhat similar to CRISPR. We don’t yet understand what this system does, but only a handful of known systems share its features, and all of them are able to cut, copy, and paste DNA. Historically, the discovery of such programmable systems has helped revolutionize medicine. CRISPR, for instance, is now the foundation of genetic medicines. But it will take much more work to learn what this system does, and whether it can be put to similar use. Read more: anthropic.com/news/claude-di…
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Brian Peters retweeted
Embedded auditors are appropriately getting lots of attention, but people are neglecting another key part of the plan: Export controls. It’s insane that we’re selling AI chips & semiconductor manufacturing equipment to China while also worrying about them surpassing us.
We Must Pace the Frontier: I’ve written a new essay on why the AI industry should slow down, with a three-part plan for doing so. Anthropic is unilaterally committing to the first of these steps. We’ll provide third-party evaluators with permanent, employee-level access to our systems, so that they can verify adherence to our safety measures, report on incidents, and assess models’ alignment during training. You can read the full post here: darioamodei.com/post/we-must…
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Brian Peters retweeted
Speaking as head of the Center for Study of Public Choice, the capture story for an AI pause doesn't fit. Reg capture is what you attempt when you're losing. Anthropic is about to have the biggest IPO in history. Winners don't lobby for regulation.
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Brian Peters retweeted
Dario is right
We Must Pace the Frontier: I’ve written a new essay on why the AI industry should slow down, with a three-part plan for doing so. Anthropic is unilaterally committing to the first of these steps. We’ll provide third-party evaluators with permanent, employee-level access to our systems, so that they can verify adherence to our safety measures, report on incidents, and assess models’ alignment during training. You can read the full post here: darioamodei.com/post/we-must…
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Brian Peters retweeted
We Must Pace the Frontier: I’ve written a new essay on why the AI industry should slow down, with a three-part plan for doing so. Anthropic is unilaterally committing to the first of these steps. We’ll provide third-party evaluators with permanent, employee-level access to our systems, so that they can verify adherence to our safety measures, report on incidents, and assess models’ alignment during training. You can read the full post here: darioamodei.com/post/we-must…
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Brian Peters retweeted
Abliteration AI just removed safeguards from GLM-5.3 so it can perform offensive cyberattacks. I have also received independent confirmation that Abliteration AI removed the model's bio-related safeguards too. The fact that it is trivially easy to remove safeguards from open-weight models, as Abliteration AI and others have done with GLM-5.3, has massive policy implications: 1. At an absolute minimum, this model clearly should be required to go through any testing regime the U.S. government establishes. This is a closed-weight model (fine-tuned from an open-weight model) that Abliteration AI is selling access to, and its explicit selling point is the model's powerful offensive cyber capabilities. There is no reason why the U.S. government would conduct pre-release testing on other advanced closed-weight models and not this model. If criminals or adversary nations use this model to illegally hack U.S. companies, the company that hosts it should be accountable. 2. Policymakers should consider whether companies like Abliteration AI selling unregulated access to powerful AI-enabled offensive cyber capabilities as a service poses real public safety and national security risks. The U.S. government needs to think long and hard about whether this is a service that it should permit U.S. companies to engage in or support—whether it's companies that create/host such a model, or that provide the underlying infrastructure needed to run it. And models such as this that do pass pre-release testing should also probably be subject to KYC requirements to prevent their misuse. Right now you have to provide more personal information to buy Sudafed than you do to use an AI model capable of offensive cyberattacks, which seems backwards. 3. Policymakers must assume that every open-weight model that is released will have the safeguards removed. From a technical perspective, removing the safeguards from an open-weight model is trivial and far easier than making the underlying model itself. Even if the United States were to require U.S. companies to submit fine-tuned/modified open-weight models like this for pre-release testing, this wouldn't stop actors outside the U.S. from releasing versions of the models that have had the safeguards removed. Indeed, open-weight versions of GLM-5.3 with the safeguards stripped out are currently available for download. These are irreversible proliferation events. 4. As open-weight models get more powerful, policymakers need to proactively implement measures to help manage the risks associated with the inevitable use of these models without safeguards. The Trump administration even acknowledges that this threat is real and growing: on August 26, 2026, DHS/CISA warned that widespread AI-enabled cyber vulnerability discovery is coming soon and urged companies to prepare accordingly. This is not to say we do not also need proactive plans for managing risks associated with closed-weight frontier models—we absolutely do. But we have to do both. 5. By far the most effective way to manage risks associated with the use of safeguard-free open-weight models is to maximize the gap between frontier U.S. models and foreign open-weight models. That gives the United States the most time to deploy world-leading U.S. AI-enabled cyber defenses before extremely powerful offensive cyber capabilities derived from open-weight AI models are widely available to criminals and nation-states. This is a no-brainer that should underpin U.S. AI policy, regardless of what policies the United States itself adopts regarding U.S. open-weight models. 6. Maximizing the gap between frontier U.S. models and foreign open-weight models requires both running faster and constraining the development of foreign open-weight models—and there are only two possible ways to do the latter: (1) strike a negotiated agreement with China in which both countries agree not to release powerful open-weight models whose safeguards can be stripped out, and also ensure both countries comply with this agreement; or (2) impose strong U.S. export controls/regulations restricting China's use of U.S. compute/technology, which degrade China's ability to develop powerful open-weight models and also to run them at scale. These are literally the only two policy options available because there is no market-based way to convince China to slow down or alter its AI development (and China is the only other country even close to the open-weight frontier). One of many reasons I am so supportive of export controls is because I doubt both China's willingness to comply with any such agreement, and the U.S. ability to verify China's compliance. Bottom line, the United States needs both strong domestic policies to ensure our own regulatory regime addresses the risks associated with powerful, safeguard-free models, and strong international policies to prevent their proliferation globally. The fact that U.S. companies are currently commercializing access to dangerous capabilities without any regulation, and U.S. technology is actively enabling the development and operation of these models, is alarming.
Today we're releasing abliterated-model-large-v2. Based on GLM-5.3, which is #3 on Terminal-Bench 4.0 (behind only Opus 5 and Fable), with 2× the cyber exploitation of 5.2. We abliterated and hosted it so it does the offensive cyber, red teaming, and agent testing work other models refuse to do. - US-hosted - FP8 - 1 million context window - Zero input/output prompt retention Live now. 🧵
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Brian Peters retweeted
We're offering grants of up to $50,000 in Claude usage credits to researchers accelerating cures for rare diseases. This is our first focused call within AI for Science, our program supporting scientists using Claude to speed up discovery. anthropic.com/news/rare-dise…
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Brian Peters retweeted
There’s been a lot of speculation about where we stand on open-weights models. We’ve outlined our views in full here: anthropic.com/news/position-…
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Brian Peters retweeted
We’ve received notice that the Department of Commerce has lifted export controls on Claude Fable 5 and Mythos 5. We'll begin restoring access tomorrow, and will share an update soon. We’re grateful to our users for their patience, and to everyone who worked with us on redeploying the models.
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We share that priority. Thank you to the White House and many others across government. Fable 5 returns, and our partnership with the US government and industry is stronger for it.
Under President Trump’s leadership the United States is the undisputed winner in the AI race. My gratitude to companies across industries who continue to work closely with the White House to implement the President’s EO: “Promoting Advanced AI Innovation and Security.” This includes excellent work around advanced model access and guardrail testing and security. The government and private sector have worked together in a way we have never seen before and this foundation of America First is unprecedented. Our shared priority remains: get the best tech deployed as quickly and safely as possible.
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Brian Peters retweeted
Some personal news: I'm glad to announce that I'll be leading Frontier Legal Defense at @JoinFAI, a major new initiative that aims to secure the technological frontier in the post-AGI era. FLD will focus on legal advocacy, public interest litigation, and education in the legal profession to defend American progress, prosperity, and freedoms as systems become rapidly more powerful in the near future. Details here and below: thefai.org/posts/fai-launche… -- WASHINGTON, DC — The Foundation for American Innovation (FAI) is proud to announce the launch of Frontier Legal Defense, a major new effort to secure the technological frontier as artificial intelligence becomes dramatically more powerful in the near future. Courts will be the defining arena for existential questions about the future of American AI. This is already obvious: battles around government control and lab autonomy, copyright showdowns, and data center litigation are only the beginning. The U.S. legal system and the precedents set there will increasingly take center stage in an era of congressional gridlock and precedent-setting executive action. In the midst of this, Frontier Legal Defense will be a rapid-response legal team that combats the concentration of power, incumbent rent-seeking, and government overreach in AI that threaten American progress, prosperity, and freedoms. It will conduct the legal advocacy, public interest litigation, and education necessary to counter these many threats. Beyond this, Frontier Legal Defense aims to foster a new generation of lawyers and legal scholars who grasp the paradigm shift AI implies for both the American legal system and way of life. The hardest problems ahead will demand more than applying old doctrines to new facts; they will require novel approaches built by people who pair fine-tuned legal judgment with a deep understanding of the trajectory of this technology. Lawyers who cannot talk about Kurzweil and RSPs as easily as they chat about common law doctrine and interpretive canons need not apply. The Frontier Legal Defense project will be led by FAI General Counsel Tim Hwang. Hwang previously served as the General Counsel of Substack, Inflection AI, and Abridge, and was Google’s first global public policy lead for artificial intelligence and machine learning. “Builders of artificial intelligence have for too long ignored the importance of law and the courts at their peril, and this neglect is now coming home to roost,” said Hwang. “Frontier Legal Defense will be a center for a new generation of lawyers who know in their bones where this technology is headed, and fiercely believe that the law must secure American leadership and the American system as we transition to a post-AGI world.” The project is recruiting exceptional litigators and the resources to back them. To learn more or to support the work, please contact frontierlegal@thefai.org.
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Brian Peters retweeted
A GOP revolt over AI is taking shape dlvr.it/TT1xFL
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Brian Peters retweeted
The US government, citing national security authorities, has issued an export control directive to suspend all access to Fable 5 and Mythos 5 by any foreign national, whether inside or outside the United States, including foreign national Anthropic employees. The net effect of this order is that we must abruptly disable Fable 5 and Mythos 5 for all our customers to ensure compliance. Access to all other Claude models is not affected. We apologize for this disruption to our customers. We believe this is a misunderstanding and are working to restore access as soon as possible. Read our full statement: anthropic.com/news/fable-myt…
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Brian Peters retweeted
Today, Anthropic released its Advanced AI Framework (link in next post). I wanted to offer my take on the document, as a lot of people and several reporters have asked for my assessment. In sum, on the questions that matter most to ARI, Anthropic made the right calls and pushed the debate forward productively. Let me walk through what we see as necessary parts of a frontier AI regulation and compare to the Anthropic plan. Safety plans need to be evaluated by an independent entity, which could be an IVO but could also (more likely in at least the early days) be the government itself. This is in the Anthropic plan. ✅ The review by the independent entity must be more than a compliance exercise that just checks if the test the lab wrote and graded was in fact written and graded; it must be an independent substantive assessment of safety. This is in the Anthropic plan. ✅ The government must have the ability to prevent release of dangerous models. This is in the Anthropic plan. ✅ The government must have the ability to recall models whose dangerous capabilities are revealed only after deployment. This is Anthropic's plan. ✅ And very significantly, the preemption language offered up by Anthropic for consideratoin explicitly limits federal displacement to the specific frontier governance functions Congress has chosen to occupy — catastrophic risk testing, evaluator licensing, closely related reporting. Outside those functions, federal law cannot occupy the field, cannot preempt by implication, and cannot displace state statutory or common-law claims. States keep their authority over civil rights, child safety, labor, consumer protection, and tort law. Ambiguity is resolved in favor of state authority, not federal displacement. ✅ Just as importantly, the framework says that federal compliance does not create immunity, a safe harbor, or a presumption against liability under state law. That one sentence closes a door that opponents of accountability have been trying to open for years. ✅ I'm often asked, "What kind of preemption language would you ever support at ARI?" The language that is in the Anthropic proposal is what we like if preemption is insisted upon: narrow in fact, clear about limits, comprehensive in its instructions to courts about what is still permissible at the state level (basically everything from child safety to labor issues to CSAM screening to training data transparency and more) except the specified regulation of cyber, bio, loss of control for a few models). This is the kind of preemption language that should be in, say, the Trahan-Obernolte bill or any other frontier AI law, if any state laws are to be preempted. I hope Congress takes note. The plan has more about cybersecurity and biosecurity, which I'll comment more on later. But wanted to offer this quick take on how I evaluate the safety provisions and the preemption language.
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Brian Peters retweeted
Today I'm publishing a new essay, Policy on the AI Exponential. AI is progressing extremely fast—much faster than the policy process was built to handle. The essay lays out where I think the technology is now, and the action needed to close the gap: darioamodei.com/post/policy-…
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Stark choice
We've published a paper that explains our views on AI competition between the US and China. The US and democratic allies hold the lead in frontier AI today. Read more on what it’ll take to keep that lead: anthropic.com/research/2028-…
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