@PerryChem

Synthetic Organic Chemistry Group @UoSChemistry

 Southampton, UK
perrychem.net
Joined June 2021
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  • Following450
  • Followers722
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Our work on Decarboxylative Metal-Halogen Exchange has been higlighted in @OPRD_ACS 💡 Thank you to the team behind the OPRD highlight 🙇 pubs.acs.org/oprdfk/article/…

Some Items of Interest to Process R&D Chemists and Engineers

Disappearing polymorphs are kinetically favorable, but under certain conditions they can transform into a more thermodynamically stable form, a so-called l

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Well done to Danny who led this work and @KenYamazaki5 for the great collaboration. You can read the original work here: pubs.acs.org/jaaucr/article/…

Aryl Halide Carboxylation via Decarboxylative Metal–Halogen Exchange

Abstract. A unique mode of metal–halogen exchange is reported for the carboxylation of aromatic halides. The process is mediated by the potassium salt of a

pubs.acs.org
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I always enjoy the energy that new group members bring 🌞 Excited to be working with this team over the next year.
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Our work with Sally Bloodworth at the Physical Sciences Data Infrastructure (PSDI) has been published in Synlett @thiemechemistry 👉thieme-connect.com/products/… We hope this contributes positively to the ongoing discussion on reproducibility in organic synthesis.
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Well done to all invovled, particularly Grace and Jazmine who led some of this work during their undergraduate degrees @UoSChem_ChemEng
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Thanks to Paul Richardson (Pfizer) for highlighting our recent work in Synfacts @thiemechemistry 💡 Synfacts link: doi.org/10.1055/a-2896-5397 The work was led by Danny Ryder and involved a great collaboration with @KenYamazaki5. Original paper: doi.org/10.1021/jacsau.5c015…
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Thanks to @CambeiroChem and @KLchemistry for hosting me @UniofGreenwich. A beautiful campus steeped in maritime history ⚓️ (...and a distillery nearby 🍸). Great discussions with fantastic staff and super bright students! Looking forward to #Syntech2026 in July.
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Our review on CO2 Transfer and Carbon Isotope Exchange is out in Organic Chemistry Frontiers. @RoySocChem Thank you to the editors for the highlight in their Emerging Investigator Series 🙇 pubs.rsc.org/en/content/arti… @UoSChem_ChemEng , @AstraZeneca

Carbon isotope exchange and transfer reactions involving CO2

Carboxylation reactions are fundamental transformations in organic chemistry, enabling the synthesis of diverse and valuable compounds, including polymers,

pubs.rsc.org
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Well done to the team, especially Grace Beaver who set off this pursuit by doing a fantastic job in their 3rd year undergraduate literature review project.
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Our latest work on Dual-Function Reagents is now out in @ChemCommun. Thank you to the editors for the highlight in their Emerging Investigator Collection 🙇 Fantastic work led by Katherine Marris 🥼 Great team effort @UoSChem_ChemEng, @AstraZeneca 🎉 pubs.rsc.org/en/content/arti…

Switchable N–H vs. C3–H carboxylation of indoles using dual-function reagents

The carboxylation of indoles through a CO2 transfer reaction with carboxylate salts is described. By altering the reaction conditions either N–H or C3–H ca

pubs.rsc.org
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Our work on Decarboxylative Metal-Halogen Exchange is out now in JACS Au @ACSPublications 🙌 Brilliant work by Danny Ryder 🥼 and a great collaboration with @KenYamazaki5 💻 pubs.acs.org/doi/10.1021/jac…

Aryl Halide Carboxylation via Decarboxylative Metal–Halogen Exchange

Abstract. A unique mode of metal–halogen exchange is reported for the carboxylation of aromatic halides. The process is mediated by the potassium salt of a

pubs.acs.org
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Check out the robustness screen in the SI too - it nicely illustrates the tolerance that this metal-halogen exchange-type process has towards ketones, nitriles, alkyl halides and more! 💪
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A Para-Selective Kolbe-Schmitt Reaction out now in @angew_chem 🚨 onlinelibrary.wiley.com/doi/… No need for high-pressure CO2, excessive temperatures or stringently dry conditions. Our carboxylating reagent unlocks a simple Kolbe-Schmitt-type reaction with unique para-selectivity.

A Para‐Selective Kolbe–Schmitt Reaction

Discovered over 150 years ago, the Kolbe–Schmitt carboxylation has established itself as one of the most well-known chemical reactions. However, the process often requires extreme pressures and high...

onlinelibrary.wiley.com
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Great collaboration with Professor Kong at Beijing University of Chemical Technology and well done to Xia Liu for driving the project forward! 🤝
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ジベンゾチオフェンジオキシドの光還元的分子変換に関するPerry Group @PerryChemとの共同研究が、Chem. Sci.誌@ChemicalScienceに公開されました！ Check out our latest collaboration paper in pubs.rsc.org/en/content/arti…

Photoredox catalysed reductive cleavage of dibenzothiophene dioxides enabled by a temperature-con...

The cleavage of C–S bonds in dibenzothiophene dioxides under reductive photoredox catalysed conditions is reported. The reactions afford sulfinates, which

pubs.rsc.org
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We have a fully-funded PhD position available in our group. For those interested in organic synthesis and developing their lab skills. Feel free to get in touch for informal enquiries. findaphd.com/phds/project/ne…

New reagents and reactions for isotope labelling at University of Southampton on FindAPhD.com

PhD Project - New reagents and reactions for isotope labelling at University of Southampton, listed on FindAPhD.com

findaphd.com
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Open to UK students and those eligible for a Horizon Europe fee waiver list: southampton.ac.uk/study/fees… Other international applicants will have to be competitive to apply for a Presidential bursary: southampton.ac.uk/study/fees…
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Brilliant teamwork! Great watching this project grow by connecting chemists and engineers based in the UK and Japan. Congrats all! 🤝 pubs.rsc.org/en/content/arti… @SiyuanWang0329, @KenYamazaki5, @a_m_nightingale, @yorimitsu_lab @UoSChem_ChemEng, @unisouthampton, @KyotoU_News

Photoredox catalysed reductive cleavage of dibenzothiophene dioxides enabled by a temperature-con...

The cleavage of C–S bonds in dibenzothiophene dioxides under reductive photoredox catalysed conditions is reported. The reactions afford sulfinates, which

pubs.rsc.org
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Great to have Giannis, Alex, Grace and Emma join us as PDRAs and 4th Year MChem students 🤝 Also welcome back Siyuan Wang - he did an MRes project with us and enjoyed it so much he has stayed for a PhD. Exciting to see the group grow!
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Amazing news! Congratulations Professor Murakami! You have given Greg and the Perry Group lots of support over the years so we are super happy that you and your team are doing so well! 🥳
Murakami Lab@LabMurakami1 Oct 2025
10月1日付で村上准教授が関西学院大学理学部の教授に昇進しました。今後ともよろしくお願いします。 「これまで支えてくれた皆様に感謝申し上げます。ラボ一丸となって、さらに研究を楽しんでいきます。KM」 Dr. Murakami has been promoted to full Professor at Kwansei Gakuin University.
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