@PearsonLab1

Researchers in the Pearson laboratory investigate oncogenic growth signalling networks as therapeutic opportunities to treat cancer

 Peter MacCallum Cancer Centre
petermac.org/research/labs/rick-pearson
Joined August 2019
  • Tweets137
  • Following76
  • Followers233
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Celebrating the retirement of my mentor and friend @PearsonRick He worked for @PeterMacRes 40% of his life and I worked with him 32% of my life! The best work comes when we work with people we like, trust &. respect. We celebrated @SVIResearch where he started as a PhD student
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📢 @PeterMacCC say they are using techniques from astronomy and ecology to help cancer research 🌌🔬 #CancerResearch #ScienceAdvances scimex.org/newsfeed/peter-ma…
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PearsonLab retweeted
Anna Trigos@anna_t_g15 May 2023
Have spatial tissue data but not sure what methods or R packages to use for the analysis? Our paper describing SPIAT for spatial analysis and spaSim to simulate tissue spatial data is now out in Nature Communications! @PeterMacRes @PMPostdocs @PearsonLab1 nature.com/articles/s41467-0…

Spatial analysis with SPIAT and spaSim to characterize and simulate tissue microenvironments

Nature Communications - Spatial proteomic data serve to provide cell-level location information for the extraction of biological features from tissues, but analyzing such data can be difficult....

nature.com
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All exercise is beneficial but for cell health, train longer @LuigiFontanaMD @KeefeChan1 smh.com.au/lifestyle/health-…

All exercise is beneficial but for cell health, train longer

Going for a long run or ride might give your body the gift of youth, new research suggests.

smh.com.au
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PearsonLab retweeted
Anna Trigos@anna_t_g20 Dec 2022
I'm so grateful for having received an NHMRC Ideas grant to study cancer ecosystems in prostate cancer using spatial technologies and developing new methods. Looking forward to the years ahead! @PeterMacRes @PearsonLab1 @PMPostdocs @PCF_Science @gu_onc petermac.org/news/six-nhmrc-…
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Continuing the tradition of playing bad Santa and good times with my old lab ⁦@PearsonLab1⁩ in a joint Xmas lab function. Happy Xmas!
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Congratulations to our two Honours students Sirui (Cathy) Weng and Yuxi Cao for presenting their final talks this week. Both have accomplished a lot this year and we are very proud of them! @PearsonRick @anna_t_g @JianKan60899540 @elaine_sanij @KeefeChan1
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PearsonLab retweeted
Anna Trigos@anna_t_g11 Jul 2022
Our work using spatial analysis to investigate the tumour immune microenvironment of prostate cancers with DNA repair mutations is now out in @jitcancer -> jitc.bmj.com/content/10/6/e0…

Tumor immune microenvironment of primary prostate cancer with and without germline mutations in...

Background Aberrations in homologous recombination repair (HRR) genes are emerging as important biomarkers for personalized treatment in prostate cancer (PCa). HRR deficiency (HRD) could affect the...

jitc.bmj.com
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Let's talk about how 😴 can stop some cells forming cancers. Firstly, many cancers are driven by the inappropriate activation of molecules that control the growth of normal cells.
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In this study, @PearsonLab1 showed that the enzyme cystathionine-beta-synthase (or CBS for short) is required to keep sleeping cells asleep rather than turning cancerous.
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We are delighted to share our latest work "Cystathionine-ß-synthase is essential for AKT-induced senescence and suppresses the development of gastric cancers with PI3K/AKT activation" published in @eLife today! elifesciences.org/articles/7… /1

Cystathionine-β-synthase is essential for AKT-induced senescence and suppresses the development of...

Cystathionine-β-synthase is a novel metabolic regulator of AKT-induced senescence and a potential tumor suppressor in gastric cancer pathogenesis which can be harnessed to target PI3K/AKT-driven...

elifesciences.org
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Our study highlights the role of CBS in regulating AIS and raises the possibility that manipulating CBS can be a metabolic strategy to target PI3K/AKT-driven cancers. /10
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Thank you to @eLife for a constructive review process that has resulted in a stronger manuscript. An amazing effort by @PearsonLab1 @PeterMacRes @zhuhaoran1992 @KeefeChan1 @elaine_sanij @anna_t_g @PearsonRick @JianKan60899540 ! #senescence
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