@PascalSati

Director, Neuroimaging Program at Cedars-Sinai

Joined December 2020
  • Tweets35
  • Following86
  • Followers78
3Media
Latest NAIMS consensus paper out!Imaging chronic active lesions. PRL SEL PET. Tremendous work by Francesca Bagnato @VanderbiltU with a v special mention in acknowledgments. Definition is 1st step in dx biomarker @danielsaloreich @PascalSati @takishinohara academic.oup.com/brain/artic…
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Patrick presenting prelim results from our LA Barbershop neurocognitive pilot study @JenHarrisMD @PascalSati @SmidtHeart @CedarsSinaiMed Thank you #JonaGoldrichCenter for funding this important work 🧠
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Great picture from @FLOTUS’s visit last week to advance research on women’s health. Meeting the needs of everyone. That includes women. Thank you for prioritizing this, FLOTUS & @POTUS ♥️💃🏻🫀 @CedarsSinai @SmidtHeart @WomensHeartCS @SecBecerra @tedlieu @mariashriver @JanetWeiMD – at Los Angeles, CA
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I may never have this chance again but today was remarkable to talk to @FLOTUS @mariashriver @tedlieu @SecBecerra @WHRYale about Women’s Heart Health and the need for more research in this area. We must focus on the inclusion of women in research and fund this!
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Cedars-Sinai was honored to welcome First Lady Jill Biden to tour our research labs & discuss women's health. @flotus is committed to supporting and advancing women's health research, inspiring innovation & investment that undoubtedly helps women today, and generations to come.
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Pascal Sati retweeted
Dan Ma@MRI_Dan29 Aug 2023
We are hiring a Siemens MR Research Scientist for a full-time position in Cleveland, funded by my Academic Industry Partnership grant. Explore this exciting opportunity and apply today ! jobs.siemens-healthineers.co…
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Our Graduate School @CedarsSinai is accredited! Stay tuned for our brand new PhD program coming in 2025!
Cedars-Sinai Academic Medicine@CedarsSinaiMed29 Aug 2023
The Graduate School of Biomedical Sciences at Cedars-Sinai has again been accredited by @wascsenior in recognition of the academic medical center’s higher education program for exceptional quality, integrity and innovation. ceda.rs/3OM2qRk
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Congratulations Tianle!!!
Cedars-Sinai Biomedical Imaging Research Institute@csmcbiri15 Jun 2023
Congratulations to Tianle Cao, winner of the 🥇First Place Young Investigator Award from the OCSMRM for his paper "Free-breathing, non-ECG, simultaneous myocardial T1, T2, T2*, and fat-fraction mapping with motion-resolved cardiovascular MR multitasking" doi.org/10.1002/mrm.29351
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Direct synthesis of multi-contrast brain MR images from MR multitasking spatial factors using deep learning doi.org/10.1002/mrm.29715 Now you can get standard clinical weighted image contrasts for "free" from a quantitative Multitasking scan
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Great opening lecture by Dr. Andrew Solomon on #MS misdiagnosis and use of the Central Vein Sign. #CMSC2023
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Great work by BIRI/@BioEngUCLA PhD student Shihan Qiu and colleagues, supervised by @yibinxiephd and @Li_Debiao!
Anthony G. Christodoulou@AGChristodoulou31 May 2023
Direct synthesis of multi-contrast brain MR images from MR multitasking spatial factors using deep learning doi.org/10.1002/mrm.29715 Now you can get standard clinical weighted image contrasts for "free" from a quantitative Multitasking scan
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Want to detect remyelination in a good model of early multiple sclerosis? Here's how we do it. In vivo MRI is sensitive to remyelination in a nonhuman primate model of multiple sclerosis doi.org/10.7554/eLife.73786 @PascalSati @AfonsoCSilva @BenIneichen

In vivo MRI is sensitive to remyelination in a nonhuman primate model of multiple sclerosis

Spontaneous remyelination is a common phenomenon in the marmoset experimental autoimmune encephalomyelitis model, reliably detected using in vivo magnetic resonance imaging, rendering this an...

elifesciences.org
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Congratulations to Anthony Christodoulou, PhD (@AGChristodoulou) on his promotion to Associate Professor! Dr. Christodoulou's lab develops multidimensional quantitative MRI techniques for diagnosing, predicting risk, and monitoring treatment of cardiovascular diseases and cancer
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Is it time to simplify the diagnosis of #MultipleSclerosis The #cvs is a possible solution! @PascalSati @JeffCohenMD @takishinohara @danielsaloreich @ClevelandClinic @JAMANeuro jamanetwork.com/journals/jam…
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The central vein sign in Multiple Sclerosis is highly specific and underutilised for the diagosis of #MS. If you are a Neurology trainee in the UK and want to lead a multicentre service improvement project get in touch. @ABNTrainees @MRIman_9
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Recent findings raise hopes for an eventual noninvasive method for the early diagnosis of multiple sclerosis: cle.clinic/3W69sT3
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This was excellent work done by @Karl0CB in the NAIMS CAVS-MS pilot team effort with @PascalSati @takishinohara @danielsaloreich and Andy Solomon. Also our prospective multi center study is fully enrolled!
Cleveland Clinic MD
@CleClinicMD8 Dec 2022
Recent findings raise hopes for an eventual noninvasive method for the early diagnosis of multiple sclerosis: cle.clinic/3W69sT3
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Fascinating study on postmortem quantitative MRI in multiple sclerosis, co-authored by @NeurosciencesCS and BIRI Prof. @PascalSati
Brain Pathology@brainpathol9 Dec 2022
Postmortem quantitative MRI disentangles histological lesion types in #MultipleSclerosis @ThINk_Basel @UniSpitalBasel @UniBasel_en onlinelibrary.wiley.com/doi/…
Examples of histopathological lesion types and their correspondent quantitative MRI (qMRI) (MTR, magnetization transfer ratio; MWF, myelin water fraction; QSM, quantitative susceptibility mapping; qT1, quantitative T1; FA, fractional anisotropy; RD, radial diffusivity). (A) Inactive lesion, not showing presence of inflammatory cells; (B) Active lesion, containing numerous microglia/macrophages also in the center; (C) Chronic active lesion, showing presence of activated microglia/macrophages at the edge; (D) Remyelinated lesion (shadow plaque), showing uniformly pale myelin stain across the whole lesion area.

ALT Examples of histopathological lesion types and their correspondent quantitative MRI (qMRI) (MTR, magnetization transfer ratio; MWF, myelin water fraction; QSM, quantitative susceptibility mapping; qT1, quantitative T1; FA, fractional anisotropy; RD, radial diffusivity). (A) Inactive lesion, not showing presence of inflammatory cells; (B) Active lesion, containing numerous microglia/macrophages also in the center; (C) Chronic active lesion, showing presence of activated microglia/macrophages at the edge; (D) Remyelinated lesion (shadow plaque), showing uniformly pale myelin stain across the whole lesion area.

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BIRI is hiring! We have openings for staff and researchers at our world-class imaging institute in sunny LA 🌞 1. Clinical Research Coordinator: jobs.cedars-sinai.edu/job/lo… 2. Postdoc in Han lab: jobs.cedars-sinai.edu/job/lo… 3. Postdoc in @AGChristodoulou lab: jobs.cedars-sinai.edu/job/lo…
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A new multicenter study in multiple sclerosis found that Gd contrast agent increases diagnostic sensitivity of the Central Vein Sign on 3T FLAIR* scans The work was led by Drs. @PascalSati of @CedarsSinaiMed, @DanOntaneda of @CleClinicMD, and @danielsaloreich of @NINDStrials
AJR@AJR_Radiology18 Aug 2022
The postcontrast FLAIR* sequence should be considered for central vein sign evaluation in future investigational trials and clinical practice. ajronline.org/doi/abs/10.221…
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