Studying the crosstalk between metabolism and inflammation in cardiac disease
Pittsburgh, PA, USA
Joined January 2020
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Paper from our lab: Targeting the macrophage epigenome in vivo. Macrophage-specific delivery of histone demethylase inhibitors using targeted nanoparticles reprograms inflammation and advances cell-specific epigenetic therapy. @Niranjana89 @jishnu1729 doi.org/10.1016/j.jbc.2026.1…
A new study from our lab shows miR-499 in platelet-derived extracellular vesicles triggers hematopoiesis after MI. Congratulations to my previous student Lee Ohayon-Steckel and @Niranjana89 @AarushDutta2010 @Krispy-ed, Yoel Sadovsky, and Bing Wang: ahajournals.org/doi/10.1161/…
Partha Dutta lab retweeted
Platelet-derived extracellular vesicles generated after myocardial infracture induces hematopoietic stem and progenitor cells proliferation - highlight potential new therapeutic targets @ParthaDuttaLab @Krispy_ed @ParthaDuttaLab ahajrnls.org/4a0Wy2E
Partha Dutta lab retweeted
Thoughtful editorial perspective by Ebin Johny and @ParthaDuttaLab on the importance of the spleen in healing the heart after myocardial infarction. #cardiosplenic axis!
Circulation ahajournals.org/doi/full/10.…
Partha Dutta lab retweeted
Congratulations to Dr. Partha Dutta, who was recently promoted to Professor of Medicine with tenure in the Division of Cardiology and Vascular Medicine Institute! 👏🎊👏
A new publication from our lab: How aberrant mitochondrial DNA synthesis in macrophages affects inflammation and atherosclerosis. rdcu.be/dR2ei by @Niranjana89 Jonathan Florentin, and many collaborators- @jishnu1729 @SrutiShiva @KrithikaSRao Yingze Zhang, Sina Tavakoli
Partha Dutta lab retweeted
Huge congratulations to @ParthaDuttaLab @PittVMI for receiving the Daniel Steinberg Early Career Investigator Award!
#VascularDiscovery24 @AHAScience
Partha Dutta lab retweeted
Congratulations to Drs. Chan, Dutta, Finkel, & Newman on leading 1 of 3 new @AHA_Research SFRN Centers focused on inflammation’s role in cardiac & brain dysfunction!🎉🫀🧠
@PittVMI @AgingPitt @PittHealthSci @chansteve73 @ParthaDuttaLab @pittwirehealth
👉 newsroom.heart.org/news/rese…
Partha Dutta lab retweeted
We are excited to continue our work together! Thank you @American_Heart for the opportunity. @PittVMI
Congratulations to Drs. Chan, Dutta, Finkel, & Newman on leading 1 of 3 new @AHA_Research SFRN Centers focused on inflammation’s role in cardiac & brain dysfunction!🎉🫀🧠
@PittVMI @AgingPitt @PittHealthSci @chansteve73 @ParthaDuttaLab @pittwirehealth
👉 newsroom.heart.org/news/rese…
Hot off the press: ahajrnls.org/3LpYQMH Ischemia alters the epigenetic landscape of hematopoietic stem cells. @PittDeptofMed @PittVMI @PittCardiology
Partha Dutta lab retweeted
Coppin, Zhang, and Ohayon et al. demonstrated that epigenetic changes in bone marrowhematopoietic stem cells following peripheral ischemia propagate inflammation @ParthaDuttaLab
ahajrnls.org/3LpYQMH
Partha Dutta lab retweeted
Congrats to Dr. Samreen Sadaf of @ParthaDuttaLab for receiving an @American_Heart Postdoctoral Fellowship Award!
Samreen will understand the mechanisms of myocardial infarction-induced heart failure.
duttalab.pitt.edu/dr-samreen…
Partha Dutta lab retweeted
Congrats to Lee Ohayon of @ParthaDuttaLab for being selected as an @American_Heart Predoctoral Fellowship Award recipient!
Lee will discern the role of platelet-derived extracellular vesicles (pEV) in myocardial infarction.
duttalab.pitt.edu/lee-ohayon…
Very proud to announce that Niranjana (@Niranjana89) received a fundable score on her AHA Career Development Award. Her K99-R00 award has also been selected for funding. Thanks to @PittVMI , @PittDeptofMed , @nih_nhlbi and @AHA_Research for supporting young investigators.
Partha Dutta lab retweeted
🗞️New @NatureAging publication from @AgingPitt and @PittVMI faculty that identifies CUX1 as a regulator of p16INK4a-dependent endothelial senescence & a potential therapeutic target for atherosclerosis & other age-related diseases.
@GangLi27853100 @chansteve73 @ParthaDuttaLab
NEW: @GangLi27853100 and colleagues examine the CDKN2A/B locus using high throughput mapping of disease-associated functional SNPs and proteomics analysis of SNP-binding proteins and identify CUX1 as a regulator of p16 expression and #senescence - nature.com/articles/s43587-0…
Excited to run Pittsburgh Marathon- virtual this time.
RACE WEEKEND IS HERE! Be sure to tag us and use #MOVEPittsburgh in your celebratory posts. PLUS! Don’t forget to get your finisher certificates and so much more as part of the Virtual Experience presented by @DICKS and @brooksrunning - find it at bddy.me/3e9GkY0!
Partha Dutta lab retweeted
Editor's pick: Hot off the press review article by Peter Libby published @Nature discusses the changing face of #atherosclerosis 👇🏼nature.com/articles/s41586-0…
#vascularbiology #inflammation #cholesterol #clonalhematopoiesis #adaptiveimmunity #innateimmunity #clinicaltrial
Congratulations to Jonathan for receiving United Therapeutics Jenesis Innovative Research Award. @chansteve73 @PittVMI
Partha Dutta lab retweeted
Join us tomorrow at noon for our VMI/HVI Distinguished Lecturer series featuring Ira Tabas, MD, PhD!
Looking forward to the VMI/ HVI Distinguished lecture by @LabRandolph at 12 pm today!
