@PaquetLab
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#iPSC models and #CRISPR to investigate mechanisms of neuropsychiatric and -vascular disorders, Professor of Neurobiology @ISD_Research @LMU_Muenchen
Munich, Germany
Joined January 2018
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Very happy to be at the Barcelona #B4event meeting and present our work this afternoon on a novel fully #iPSC based model of the #BBB that allows investigating neurovascular diseases!
📆 D-Day
🎉 B4 is officially starting today!
Welcome to all participants — let’s make this edition a memorable one filled with knowledge, exchanges, and scientific breakthroughs.
Stay tuned and share your experience with #B4event!
#OpeningDay #NeuroscienceConference
Open Postdoc position where we still accept applications for a few more days. Please RT and apply!
Open #Postdoc position @isd_research @LMU_Muenchen to develop an #iPSC-derived #BBB model. Fully funded and embedded in our international @FondationLeducq Network of Excellence brenda-leducq.de/. Experience in vascular biology or related field required. Please RT and apply!
Open #Postdoc position @isd_research @LMU_Muenchen to develop an #iPSC-derived #BBB model. Fully funded and embedded in our international @FondationLeducq Network of Excellence brenda-leducq.de/. Experience in vascular biology or related field required. Please RT and apply!
We @PaquetLab are now also present on Bluesky. Please follow us: bsky.app/profile/paquetlab.b…
Congratulations Matthias Tschöp and @LMU_Muenchen !
Herzlichen Glückwunsch, Matthias Tschöp. Der derzeitige CEO des @HelmholtzMunich wurde heute zum neuen Präsidenten der LMU gewählt. Seine sechsjährige Amtszeit beginnt am 1. Oktober 2025. lmu.de/de/newsroom/newsueber…
Fantastic work, big congrats to the entire @ArthurLiesz lab!
Super exited to share that my postdoc work in @ArthurLiesz lab is finally published in @CellCellPress today!! 🥳
We have identified immune memory after stroke, leading to chronic inflammatory cardiac dysfunction.
cell.com/cell/fulltext/S0092…
Big thank you again to our fantastic guest speaker Moritz @mhelmstaedter @mh_lab from @MpiBrain for a really inspiring talk about #connectomics!
ISD teams gathered for annual scientific retreat to present their projects and discuss work. There were presentations from Ph.D. students, a poster session, invited speaker talks, and an amazing three minute thesis competition. @PaquetLab @JekyllSarah @mgeorgakis1
Dominik Paquet retweeted
Don't miss Stephanie Fesser from BioNTech, discussing "Design and Production of mRNA Therapeutics." Join us for a deep dive into the future of medicine!
➡️Lynen Lecture Hall 🕐June 10 at 1:15 pm
Correct link to University news about our recent study: lmu.de/en/newsroom/news-over…
#LMU researchers have developed a promising #genetic treatment #method for #frontotemporal #dementia and successfully tested it on mouse models and human neurons in the lab. @LMU_BMC #medicine #treatment #research lmu.de/en/newsroom/news-over…
Excited to share a new paper from a close collaboration between @Haass_Lab, Denali and our lab, led by shared grad student @marvinreich93 and Matt Simon. Overview below and full paper here: science.org/doi/10.1126/scit…. Big congrats Matt and Marvin and many thanks to all involved!
Can we achieve protein replacement in the brain using a single dose gene therapy approach, without infecting the brain? Yes we can! Read it here in our latest paper by @marvin_reich in collaboration with Denali Therapeutics science.org/doi/10.1126/scit… (1/8)
Dominik Paquet retweeted
📜📸 Some quick snapshots from yesterday's evening at EMBL Barcelona: a poster session and dinner to finish Day 2 of the EMBO Workshop 'Building networks 2024: engineering in vascular biology' #EMBOBuildNetworks
Great to be at #EMBOBuildNetworks and present a talk about our fully #iPSC derived model of the #bloodbrainbarrier! Please contact me in person or via email for further questions. 🙂@EMBLEvents
☀️🤓 The weather outside may be lovely but we've all gathered at EMBL Barcelona to present latest research and listen to excellent talks which our programme is packed full of! #EMBOBuildNetworks
A poster session followed by dinner still ahead of us today 📜🍽️
Many thanks Nuria Almiñana @VHIR_ for the talk invitation and great discussions with the research community about the potential of #iPSC models for investigating mechanisms of brain diseases!
At the next #VallHebronTalks by #VHIR, Dr. Dominik Paquet @PaquetLab (@ISD_Research - @LMU_Muenchen) will present 'iPSC- and CRISPR-based 3D brain tissue models recapitulate key features of neurodegenerative and neurovascular diseases'.
🗓️ 2/5 - 3 p.m.
ℹ️ vallhebron.social/talk-paque…
Dominik Paquet retweeted
For all Array Tomography enthusiasts: Apply now for our AT workshop in Munich, Germany: arraytomography.org/workshop…
#volumeEM #CZI #arraytomography #CLEM #electronmicroscopy
Big congrats to Carolina Gonçalves from the lab for winning the best poster prize at #StemCellTuebingen meeting 2024!
Dominik Paquet retweeted
Imaging Structure & Function in the Nervous System Course @ Cold Spring Harbor.
Application deadline 31st March!
In-vivo microscopy, optogenetics, behavior, -omics, data analysis… lectures, hands-on labs, builds, projects, guest speakers, TAs, vendors...
July 23-Aug 13 2024
ALT Apply to Imaging Structure and Function in the Nervous System at Cold Spring Harbor Labs. https://rb.gy/026qb5
Congrats to all organizers for another fantastic #StemCellTuebingen meeting! Great overview of #iPSC based neuroscience in Germany, Europe and beyond! And congrats to all awardees including our own Carolina Gonçalves!
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Many thanks Zoltan - was really nice to collaborate and have so many fruitful discussion on the #iPSC side of the project!
Did you know Alzheimer's disease might be linked to 3D genome folding? Our new preprint explores the connection! biorxiv.org/content/10.1101/…
#Alzheimer #3Dgenome, #chromatin
