@PMC_modularity

Global community driving the study of short linear motifs, modular protein domains, molecular pathways and signaling in cell regulation, health and disease.

proteinmodules.org/
Joined September 2022
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  • Followers52
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PMC Protein Modules Community retweeted
PMC Protein Modules Community@PMC_modularity15 Aug 2025
We are back with an exciting seminar on September 8 at 3pm CEST. We’ll hear from Prof. Birthe Kragelund (@BBKrage) and Maximilian Vieler (@VielerMax). Register to attend: tinyurl.com/PMCseminar2 Recordings of previous seminars: youtube.com/@PMCModularity
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EMBL Heidelberg@EMBLHeidelberg12 Nov 2024
💥 We’re hiring! 💥 In the @EMBLHeidelberg Genome Biology Unit we study genotype to phenotype links with genomics, genetics & computational methods. We’re looking for two group leaders to join us! 🗓 Apply by 2 Jan 2025 More info: embl.org/jobs/position/HD027… embl.org/jobs/position/HD027…
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PMC Protein Modules Community retweeted
Evangelia Petsalaki@e_petsalaki16 Oct 2024
I'm pleased to share that I will be speaking at The Festival of Genomics & Biodata, taking place on the 29th-30th of January 2025 at ExCeL London. Registration is free for over 90% of attendees - register now to join me in January. hubs.la/Q02TptWZ0 #FOG2025

The Festival of Genomics and Biodata London

The UK’s largest Life Sciences event returns to London

festivalofgenomics.com
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PMC Protein Modules Community retweeted
Kevin Drew@kdrew16 Oct 2024
Excited to share our preprint describing hu.MAP3.0. Here we integrate >25k mass spectrometry experiments to place ~75% of human proteins into 15k protein complexes. biorxiv.org/content/10.1101/…

hu.MAP3.0: Atlas of human protein complexes by integration of > 25,000 proteomic experiments

Macromolecular protein complexes carry out most functions in the cell including essential functions required for cell survival. Unfortunately, we lack the subunit composition for all human protein...

biorxiv.org
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PMC Protein Modules Community retweeted
Short Linear Motif team@DaveyLab12 Sep 2024
Have you ever wondered how many of the human SLiMs are required for cell viability? We mutated them all to find out in another extremely fun collaboration with the @NilssonLabCph group. The results are now on bioRxiv biorxiv.org/content/10.1101/…. Check it out!

A proteome-wide dependency map of protein interaction motifs

Short linear motifs (SLiMs) are the most ubiquitous protein interaction modules in the unstructured regions of the human proteome. Despite their central role in protein function, our understanding of...

biorxiv.org
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PMC Protein Modules Community retweeted
Short Linear Motif team@DaveyLab6 Sep 2024
Excited to present a new docking motif for IKK (Inhibitor of κB (IκB) kinase)! A great collaboration with the Zanier lab at the ESBS showed a YDDΦxΦ motif in IκBα, IκBβ and p100 recruits IKK. nature.com/articles/s41467-0…
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PMC Protein Modules Community retweeted
The Nobel Prize
@NobelPrize5 Oct 2022
BREAKING NEWS: The Royal Swedish Academy of Sciences has decided to award the 2022 #NobelPrize in Chemistry to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless “for the development of click chemistry and bioorthogonal chemistry.”
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PMC Protein Modules Community retweeted
Gary Bader@garybader13 Oct 2022
Way to go @duncanforster and Sheena Li. Amazing team with Charlie Boone, @BoWang87 and @riken_en and @UTokyo_News_en @UofT @DonnellyCentre @VectorInst nature.com/articles/s41592-0…

BIONIC: biological network integration using convolutions

Nature Methods - BIONIC uses a deep learning framework for accurate and scalable integration of biological networks.

nature.com
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PMC Protein Modules Community retweeted
The Nobel Prize
@NobelPrize3 Oct 2022
BREAKING NEWS: The 2022 #NobelPrize in Physiology or Medicine has been awarded to Svante Pääbo “for his discoveries concerning the genomes of extinct hominins and human evolution.”
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PMC Protein Modules Community retweeted
Evangelia Petsalaki@e_petsalaki15 Sep 2022
Aaaand it’s a wrap! #embosignalling22 Thanks to everyone for making this yet again and awesome meeting!
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PMC Protein Modules Community retweeted
Evangelia Petsalaki@e_petsalaki12 Sep 2022
Enjoying the beautiful scenery with old friends #embosignalling22
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PMC Protein Modules Community retweeted
Evangelia Petsalaki@e_petsalaki12 Sep 2022
Great last session of the day with flash talks, @LindingLab, Livia Perfetto, and Dev Sidhu!
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PMC Protein Modules Community retweeted
Evangelia Petsalaki@e_petsalaki13 Sep 2022
Fantastic session with beautiful structures, SLCs, role of linkers in tethering functions of SLiMs and more! #embosignalling22
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PMC Protein Modules Community retweeted
Evangelia Petsalaki@e_petsalaki14 Sep 2022
Mike Yaffe kicks off the day with spectacular talk on a Rosetta Stone for translating phosphodata to signalling. Check latest work on bioRxiv!
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PMC Protein Modules Community retweeted
Evangelia Petsalaki@e_petsalaki14 Sep 2022
Filip Mihalic presents cool work on the discovery of motif-mediated RNA virus- human host interactions - check bioRxiv! #embosignalling22
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PMC Protein Modules Community retweeted
Evangelia Petsalaki@e_petsalaki14 Sep 2022
Super cool last session of the day with @NilssonLabCph on the effect of coronavirus on stress granules, Stephan Feller with ground breaking work on studying the disorder to order transition of the IDP Gab1 and Panagis Filippakopoulos on avoiding toxicity from BET inhibitors
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PMC Protein Modules Community retweeted
Evangelia Petsalaki@e_petsalaki15 Sep 2022
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PMC Protein Modules Community retweeted
Evangelia Petsalaki@e_petsalaki15 Sep 2022
For this morning’s short talks @AndriiGorelik presents great work on cysteine modifications and @PavithranRavind on using a synthetic gene circuit to study signaling dynamics #embosignalling22
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PMC Protein Modules Community retweeted
Evangelia Petsalaki@e_petsalaki15 Sep 2022
Amazing keynote by Wendell Lim on how you can use modular toolkits to engineer synthetic circuits and cells with many applications including cell based therapies for targeted delivery of cytokines and other molecules.
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