Paolo A. Ascierto retweeted
🔥 Serum TKa in #BRAF metastatic #Melanoma - SECOMBIT trial in @CCR_AACR (subset, n=81)
Median split the cohort:
• 5-y OS 70.7% vs 36.9% (HR 3.08)
• 5-y total PFS 60.8% vs 35.0% (HR 2.47)
• Independent of LDH
➡️ TKa-high did better with the sandwich arm, TKa-low with upfront IO.
🎯 Good prognostic biomarker. 54% of TKa-high had normal LDH: aggressive biology you’d otherwise miss, in patients who need tumor control fast
👏@HildurHelg, @PAscierto & the rest of authors
doi.org/10.1158/1078-0432.CC…
Paolo A. Ascierto retweeted
Honored to Receive the 2026 @sitcancer Lifetime Achievement Award - @PAscierto
oncodaily.com/voices/paolo-a…
Paolo A. Ascierto retweeted
Oggi all'IRE la lecture del Prof. Ascierto ha aperto il convegno nazionale sul melanoma.
Nuovi standard terapeutici, vaccino a mRNA con dati a 5 anni solidi, e prospettive sulla tripla immunoterapia.
Leggi tutto → ifo.it/2026/06/melanoma-e-tu…
Paolo A. Ascierto retweeted
Now Published: Insights from @SITCancer experts on the surveillance and management of post-ICI delayed or chronic irAEs, including a call for an ICI RWD irAE registry. ow.ly/69oi50YwoZV
@PAscierto @kgunturuMD
#immunotherapy #survivorship
Why do IO combinations fail in adjuvant melanoma?
Because minimal residual disease lacks immune priming.
Adjuvant IO must activate immunity, not just maintain it.
With @IgnacioMelero | @jitcancer
jitc.bmj.com/content/13/12/e…
Paolo A. Ascierto retweeted
#ESMO25 | Melanoma ad alto rischio: follow up a 9 anni del CM-238 su nivolumab in adiuvante.
Il commento di Paolo A. Ascierto @PAscierto
Non perdere il contributo integrale sulla Day 3 di OncoInfo da Berlino 🔜
Paolo A. Ascierto retweeted
Melanoma resecato ad alto rischio: quali i dati a 9 anni del trial CheckMate 238 in adiuvante presentati a #ESMO25? E come si ridefinisce il ruolo di nivolumab in questo setting di pazienti? Lo abbiamo chiesto a @PAscierto shorturl.at/cnk17
Paolo A. Ascierto retweeted
#ESMO25 | Melanoma ad alto rischio: follow up a 9 anni del CM-238 su nivolumab in adiuvante.
Il commento di @PAscierto 👇
Non perdere il contributo integrale sulla Day 3 di OncoInfo da Berlino 🔜
Paolo A. Ascierto retweeted
Adjuvant Nivolumab Displays Long-Term Activity in Resected Melanoma @PAscierto @UninaIT @istitutotumori @myESMO #ESMO25 #ESMO2025 #melsm #oncology
onclive.com/view/adjuvant-ni…
Paolo A. Ascierto retweeted
Best responses included a complete response rate of 11.7%, a partial response rate of 6.4%, and a stable disease rate of 37.2%. #ESMO25 #melsm | @myESMO @PAscierto
cancernetwork.com/view/bnt11…
Paolo A. Ascierto retweeted
Congrats 🎉 @PAscierto +team on the Nivolumab long-term data in Melanoma published in @NEJM during #ESMO25 !
@myESMO
Paolo A. Ascierto retweeted
Tomorrow, Dr. @PAscierto will present the final, 9-year results from CheckMate 238, a double-blind, phase 3 study of adjuvant treatment trial in resected stage IIIB–C or stage IV #melanoma.
Join the session in Hall 7.1a at 14:45 CEST on Sat., Oct. 18 bit.ly/48wliPR
Paolo A. Ascierto retweeted
FIno a poco fa un cancro metastatico nel quale due terapie erano fallite era una partita chiusa. Oggi, grazie alla medicina di precisione, è ancora tutta da giocare. Bellissimo lavoro tutto italiano appena uscito su @NatureMedicine dei miei amici @curijoey e @PAscierto
Paolo A. Ascierto retweeted
Al 10° Annual Meeting di Alleanza Contro il Cancro ho avuto l’onore di moderare una sessione con le letture magistrali del Prof. @curijoey e del Prof. @PAscierto.
Si è discusso di terapie agnostiche e oltre l’immunoterapia: le grandi aspettative per il futuro dell’oncologia.
Wishing Gordon Ramsay a speedy recovery after surgery for basal cell carcinoma.
His reminder to “use sunscreen” is more than advice-it’s prevention.
- The sun is not our enemy — UV radiation is
- Sunscreens don’t cause cancer: they protect against it.
Paolo A. Ascierto retweeted
Every Sunburn Leaves a Mark - Raising Awareness on Skin Cancer Prevention - @PAscierto
oncodaily.com/voices/349811
#OncoDaily #Oncology #Cancer #Health #Medicine #MedX
Paolo A. Ascierto retweeted
The FDA said no to a new treatment for advanced melanoma. We're collecting stories to help them understand what that means for real people.
Share your voice: bit.ly/4f78kJi
#Melanoma #PatientVoices #FDA #AIMatMelanoma
Thanks to a request submitted @AIOM, the drug combination investigated in the NADINA trial, has been included among the treatments reimbursed by the Italian National Health Service (SSN) under Law 648/96, for use as neoadjuvant therapy in patients with melanoma.
Paolo A. Ascierto retweeted
This is Where Ideas Capable of Improving and Transforming the World Take Place - Paolo Ascierto
@PAscierto
oncodaily.com/blog/paolo-asc…
#Cancer #CancerResearch #PremioFabula #Medicine #MedX #MedNews #MedEd #Health #Oncology #OncoDaily