Aspirin + vitamin C outperformed chemotherapy for liver cancer in this study. After 90 days, the livers of rats treated with the combo looked almost identical to healthy ones. Compared to doxorubicin (standard chemo), aspirin + IV vitamin C: ◈ Better restored liver structure + function, visibly smaller tumors ◈ Lowered tumor markers (AFP, CA19.9) ◈ Lowered inflammation (IL-6, TNF-α) ◈ Restored p53, the “guardian of the genome” And in cell studies, the combo was over 3x more toxic to cancer cells than healthy cells, while chemo was not nearly as selective. More on the anti-cancer mechanisms of aspirin below.

Ice cream has some health benefits you will not believe. In fact, dairy fat in general is absolutely loaded with goodies. In one study, the MAIN component of ice cream (milk fat) almost completely obliterated the growth of these cancer cells. The researchers found the milk fat acted on similar pathways to many cancer drugs: ◆ HDAC inhibition ◆ Antioxidation ◆ pJAK-2 and pSTAT-3 suppression Pentadecanoic acid (C15) is a primary constituent of ice cream, and one study found it kills breast cancer cells, while: ◆ Reducing breast cancer stem cells ◆ Inhibiting factors involved in cancer spread Both major determinants of cancer lethality. Vaccenic acid shrinks tumors by 3-4X in experiments. Yet another fat you'll find in ice cream, trans-vaccenic acid. A study published in Nature found it: ◆ Enhances anti-tumor immunity ◆ Protects against melanoma, breast, nasal cancers The same researchers found that people with higher vaccenic acid levels tended to fare better with cancer. Conjugated linoleic acid is a PED and can eve raise testosterone. Yes, research shows another fat from ice cream literally: ◆ Stimulates the production of testosterone ◆ Improves physical performance ◆ Reduces fatigue Trans palmitoleic acid, found primarily in dairy fat, prevents obesity experimentally. Another ice cream component to crank your metabolism. In one study, it: ◆ Prevented fat gain ◆ Stopped fatty liver ◆ Increased metabolic rate By acting on PPARγ, which restores insulin sensitivity and lowers inflammation. In another experiment, vegetable oil induced atherosclerosis, meanwhile vaccenic acid rich butter reduced it. Vaccenic acid is a fat found only in dairy, and has: ◆ Anti-cancer ◆ Anti-inflammatory ◆ Lipid lowering properties. C15, found in bundles in ice cream, was shown in one study to: ◆ Reduce every inflammatory measure ◆ Reduce every fibrosis factor measure while ◆ Decreasing blood sugar ◆ Lowering triglycerides ◆ Correcting anemia in obese animals Dairy fat component literally mimics billion dollar anti-aging drugs. One study comparing them found C15 shares properties with the leading anti-aging drugs, including metformin & rapamycin. These include: ◆ Anti-inflammatory ◆ Anti-fibrotic ◆ Glucose lowering ◆ Anti-cancer ◆ Antimicrobial ◆ mTOR inhibiting Dairy fat powerfully lowers gut inflammation. In one study, vaccenic acid, again found in large amounts in ice cream, reduced pro-inflammatory cytokines in the gut, which are directly implicated in symptoms like ◆ Gut pain ◆ IBS ◆ Constipation ◆ Diarrhea ◆ Bloating & more. What IS bad about ice cream is that most commercial brands put tons of added garbage into it. ◆ Gums ◆ Dyes ◆ Emulsifiers & more. These ingredients can wreak havoc on the gut & metabolism. So make sure you get a clean brand like Haagen Dazs. This isn't to say you should be downing tons of it all the time. But it absolutely has healthful properties.

I can say confidently after working with ~1,000 people individually on their health, that the number one thing that determines success is not a diet, supplement, or anything like that. It's literally just doing something, and sticking to it. The only way you'll ever make progress in anything is by testing, experimenting, and adjusting. But that doesn't work if you don't do it to begin with. I've put together protocols that have taken me hours of biochemical analysis to do, but none of that matters when the person does 60% of it for a month, concludes it doesn't work, and then moves on to the next thing. Even when you feel like you're not making progress, you're still learning what doesn't work and even what makes things worse, which in itself is helpful information. Unfortunately modern medicine has put this thing in peoples' heads that you can come in, take this pill, and that's it. But real success in health is like real success in anything else. You need to lock in. Attention to detail. Persistence. These are what will help you in the long run. Expecting someone to come in with a miracle solution will not.

Ray Peat was wrong about a lot. Here are 10 of the big ones, why, and what else the community often gets wrong, misrepresents, or overlooks:

Do you realize how many studies show people eating AS MANY CARBS AS THEY WANT and still lose weight and improve insulin resistance? In one study, people cut their fat calories from 38%➜28%, and increased their carb intake accordingly. They were told they could eat as much as they wanted. Their weight dropped like a rock. Another trial - 3 diets, people could eat as much as they want: 1. 58% calories from carbs, 12% protein, 30% fat 2. 45% carbs, 25% protein, 30% fat 3. A 40% fat diet Diets 1 & 2 substantially reduced belly fat. Diet 3 gained weight. Another study - high carb / low fat diet drops belly fat, without reducing calories. A separate research article showed that an ~18% fat diet resulted in greater fat loss than a ~35% fat one. Same calories. A 70% carb diet helps in weight loss - without restricting calories. They actually told people to eat more to maintain their weight for the sake of the research, but they kept losing weight. It also improved their insulin resistance. One of my favorites showed that they restricted fat intake to 20-25% of calories while allowing for infinite carbs. Not only did they drop weight, but there was NO reported difference in how palatable the diets were. A 65% carb diet was shown to cause weight loss, needing to force feed people to maintain weight. 15% fat in the diet there. People needed to force feed an extra ~300-400 calories just to NOT lose weight. Crazy. Yeah you might lose weight, but your blood sugar and insulin will be through the roof, right? Nope. In fact, people reversed the signs of diabetes on the "rice diet," which was 95% carb, or about a pound of carbs daily). High carb diets used to be the standard treatment for diabetes. For example, in one trial they used an 85% carb diet and saw: ◇ Lower insulin ◇ Lower blood sugar ◇ Improved insulin sensitivity No restriction. An even crazier set of experiments showed that 80% SUGAR diets could dramatically improve insulin resistance. Yep, 80% glucose or sucrose (table sugar) had this effect. The 80% sugar diets outperformed diets that were 60, 40 and 20% sugar. INCREASED CARBOHYDRATE TOLERANCE IN DIABETICS FOLLOWING THE HOURLY ADMINISTRATION OF GLUCOSE AND INSULIN OVER LONG PERIODS. Yeah, that's the title of this next paper. Do I need to elaborate more? The key is the LOW FAT. While most of us think of junk food as being high carb, it's equally (and often higher) high fat. ◈ Chips ◈ Donuts ◈ Fried foods ◈ Cheeseburgers ◈ Pizza etc etc These foods have tons of FAT, especially if you eat out. They're often drenched in oil or have tons of butter or cheese added, or have sauces / dressings that are mostly fat. Dairy fat, coconut oil, olive oil are what I consider to be healthy fats, but even those can be overconsumed. The cutoff seems to be at around 30% of calories from fat, which really isn't difficult to hit if you make your own foods. Lower than that is often better. Fat is important to making food taste good, but we certainly don't need the amounts we eat. Commercial food just way overdoes it. The average American eats right around 35% fat, in conjunction with high carbs. That is THE fattening diet. High carb + high fat. In fact, that's what we use to fatten up animals: a high carb, high fat (seed oil) diet. WHY HIGH CARB DIETS WORK FOR FAT LOSS / INSULIN RESISTANCE: One obvious factor is that the higher fat the diet is, the more calories are eaten. Whole carb sources: ◇ Potatoes ◇ Rice ◇ High quality bread / pasta ◇ Fruits ◇ Juices These are not easy to overeat. People who are obese normally consume high carb and high fat diets. Higher carb lower fat diets are routinely associated with reduced risk of getting obese. When people are overfed / force fed extra food as either carbs or fat, people who eat extra as carbs: ◇ Have higher metabolism ◇ Gain less fat ◇ Have higher leptin secretion This is likely another reason why the infinite carb approach works so well. Obviously, you can lose weight and maintain it on a low carb / high fat diet. However, the inverse is also true, and in my view is preferable for health in the long run. Losing weight can certainly be tough, but it's important to do so in a sustainable and healthy way. Studies linked below.