Hoping this helps

@DxRxEdu @rabihmgeha

Finally, I found this incredible video right after finishing this tweetorial, it does an incredible job showing the process: youtube.com/watch?v=cYyJF_aS…

In the inner medullary collecting ducts, ADH increases both water and urea permeability, which allows urea to flow passively down its concentration gradient into the interstitial fluid.

In addition to counter-current multiplication, urea also contributes to osmotic gradients. ADH increases water permeability, but not urea permeability in the cortical and outer medullary collecting ducts, causing urea to concentrate in the tubular fluid in this segment.

The topic of counter-current multiplier has come up a few times on @UnremarkableLab so I want to tackle it without using too many numbers. I generalized some things, but I hope that doesn't take away from the magic. Would really appreciate some feedback @RosenelliEM @CPSolvers

I had the same thought!! Home gyms were never my thing, but it's such a good outlet for stress

Data looks convincing from RECOVERY, I'm thrilled, hopefully the data holds up