Physicist by training, biophysicist by passion. Founding and Managing Director of the Paris based CNRS Saint Pères Paris Institute for the Neurosciences (SPPIN)

Paris, France
Joined May 2018
We are proud to announce that our work "Label-free, high-resolution fluorescence imaging of the intestinal wall by image scanning and confocal microscopy by Marwa Moulzir*,  Doriane Hazart,* Clément Ricard✉ and me is out in Gastro Hep Adv ! Congratulations to Marwa and Doriane.
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This is the first chapter of our large work tansforming Fourier-plane imaging from an expert-dependent technique into a reproducible and scalable tool for surface-sensitive fluorescence microscopy for routine super-resolution biological imaging.
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UbiClear: a new ultra-fast and natural biological tissue clearing process erganeo.com/en/licence_Idyll…
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The SPPIN is an recruiting an optical engineer for boosting its core unit, 1-year + prospect of a science of job: emploi.cnrs.fr/Offres/CDD/UM…
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📢 Exciting new product alert with the launch of CNRS-SPPIN's UbiClear! Our new, universal, non-toxic and ultra-fast clearing is out! available at idylle-labs.com/shop/ubiclea…, UbiClear is the solution. 🔬 #Innovation #Biotech #Research
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I am very happy to share Antonin SINGER's first publication, now available as a pre-print on bioRxiv. Antonin and co-workers have revisited an enigmatic cerebellar glial cell that has long been forgotten: the feathered cell of Fañanas. Check it out: biorxiv.org/cgi/content/shor…
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And a nice example of the problems of scientific publishing: our bioRxiv (doi: doi.org/10.1101/2022.06.15.4…) has been around since June, the (not so different) final paper is out only now, and this despite a smooth and efficient review process...
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An alternative to conventional H&E staining and histology, for neuroanatomists, but also for clinicians. It's fast, it's powerful and easy. Label-free, fast, 2-photon volume imaging of the organization of neurons and glia in the enteric nervous system frontiersin.org/articles/10.…
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Just a nm-step at the sample, but a leap ahead for quantitative surface microscopies... Characterizing nanometric thin films with far-field light biorxiv.org/content/10.1101/… Check out our new work by Hodaya Klimovsky et al,. now out as a preprint. Big thanks to all co-workers!
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We did it. Coming soon on arXiv. Stay tuned.
Our new light sheet is starting to get form. Big thanks to Frédéric Brau (Valbonne) and Thierry Bastien (Paris).
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The young #investigator Cranefield #award🏅 goes to Federico Trigo, then at @Univ_Paris, now at @IIBCE👏🏽. Trigo and colleagues used cutting-edge biophysical techniques to show that the prior history of Ca2+ elevation affects release probability of vesicles that fuse…
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Fresh from the press and finally out in the Biophysical Journal: Pulse-length effects in 2P-micoscopy. I. Infrared excitation induces brain heating and calcium microdomain hyperactivity in cortical astrocytes£ cell.com/biophysj/fulltext/S…
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SPPIN's Bruno Gasnier lab together with Francine Acher's group published in J Med Chem : Dubois et al. (2020) Amino acids bearing aromatic or heteroaromatic substituents as a new class of ligands for the lysosomal sialic acid transporter sialin (SLC17A5). Congratulations !!
Our new work on SAF is out in the Biophysical J: Journal doi.org/10.1016/j.bpj.2020.0…
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Mahesh Karnani's impressive new work is out: Check out this truly original piece of work. Happy to have you soon as a group leader with SPPIN. Congratulations, MO Ultra-sparse connectivity within the lateral hypothalamus biorxiv.org/content/10.1101/…
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Along the lines of our recent Biophys. J. (authors.elsevier.com/a/1ZgGf…) we are 𝗵𝗶𝗿𝗶𝗻𝗴 a postdoc fellow interested in contributing to metrology and standardisation in biological super-resolution microscopy. Please RT and contact if interested [email protected]