Olaf Perdijk (@OPerdijk) profile picture

Olaf Perdijk

@OPerdijk

Assistant Professor of Mucosal Immunology. Focussed on interplay of gut microbiome and host metabolism and immunity.

Joined June 2023
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  • Followers76
Olaf Perdijk retweeted
NRC (@nrc) profile picture
NRC@nrcAug 6
Hoe poeppillen mogelijk een pinda-allergie verhelpen nrc.nl/nieuws/2026/08/06/hoe…
Hoe poeppillen mogelijk een pinda-allergie verhelpen

Hoe poeppillen mogelijk een pinda-allergie verhelpen

Poeptransplantatie: Deelnemers aan een kleine studie slikten 36 pillen met daarin de ontlasting van mensen zonder pinda-allergie. Na een paar maanden konden ze een handjevol pinda’s verdragen. Hoe...

nrc.nl
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Olaf Perdijk retweeted
Cell Reports (@CellReports) profile picture
Cell Reports@CellReportsJul 27
Microbial imprinting of the airway epithelium dlvr.it/TTkN6r
Microbial imprinting of the airway epithelium

Microbial imprinting of the airway epithelium

Emerging evidence highlights an important role for gut and respiratory microbes in shaping long-term respiratory health via imprinting of the airway epithelium. In this review, van de Ven et al....

cell.com
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Read the latest #SMIMemberPaper from @BenJMarsland and colleagues in @ImmunityCP on how early life #Antiboitics reduce systemic indole-3-propionic acid levels required to maintain mitochondrial respiration in the lung. bit.ly/4dhAxuK
Image from Society for Mucosal Immunology (@socmucimm)
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Olaf Perdijk retweeted
Immunity (@ImmunityCP) profile picture
Immunity@ImmunityCP17 Aug 2024
Hit me baby one more time…with microbial IPA dlvr.it/TC2hZ9
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‘@cellhostmicrobe special issue illustrates how microbial composition of specific tissues and organs systemically contributes to maintenance of homeostasis (health) or drives disease development and progression. Take a look. hubs.li/Q02LpDj30
Image from Cell Press (@CellPressNews)
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Olaf Perdijk retweeted
Immunity (@ImmunityCP) profile picture
Immunity@ImmunityCP15 Aug 2024
Antibiotic-driven dysbiosis in early life disrupts indole-3-propionic acid production and exacerbates allergic airway inflammation in adulthood dlvr.it/TByDzF
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"Antibiotic-driven #dysbiosis in early life disrupts indole-3-propionic acid production and exacerbates allergic airway inflammation in adulthood," concludes a study in @ImmunityCP. @OPerdijk #microbiota👇 cell.com/immunity/abstract/S…
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I am very grateful to @NatRevImmunol for highlighting our recent publication! Special thanks to Lucy Bird for doing a fantastic job in summarizing our findings in such detailed yet concise way. dlvr.it/TBDkcN
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Early life antibiotics have lasting effects on the lung epithelium dlvr.it/TBDkcN
Image from Nature Rev Immunol (@NatRevImmunol)
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Systems immunology is not only immunology with more data. It is a new way of thinking about immune systems as integrated multiagent systems w particular value for making variable human immune system more interpretable: cell.com/trends/immunology/f…

Making human immune systems more interpretable through systems immunology

The human immune system is a distributed system of specialized cell populations with unique functions that collectively give rise to immune responses to infections and during immune-mediated diseas...

cell.com
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📚 Just published a BCR repertoire sequencing protocol! This is the result of a great collaboration with Prasanti Kotagiri, Rachael Bashford-Rogers and @vanessabryantoz. Thanks to editor @KimLJacobson for the opportunity! link.springer.com/protocol/1…

Human B Cell Receptor Repertoire Sequencing

Next-generation sequencing has the potential to uncover the complex nature of B cell immunity by revealing the full complexity of B cell receptor (BCR) repertoires in health and disease. However,...

link.springer.com
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Olaf Perdijk retweeted
Eric Topol (@EricTopol) profile picture
Eric Topol
@EricTopol22 Jul 2024
Proteins, proteins, proteins. How 3,000 blood proteins can help predict 10-year risk of >200 common and rare diseases, beyond genomic markers nature.com/articles/s41591-0… @uk_biobank @NatureMedicine
Image from Eric Topol (@EricTopol)
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Media coverage continues on research led by @BenJMarsland and @OPerdijk on #asthma and antibiotic use in infancy, centring on the molecule IPA. youtube.com/watch?v=XJoMGIj4…
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Melbourne researchers have unlocked why children are more likely to develop asthma after early exposure to antibiotics. Professor Ben Marsland speaks to @mikeamor7 about the research. 7NEWS.com.au #7NEWS
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🇦🇺 Asthma Breakthrough ▫It’s one of asthma’s biggest causes and can begin in babies, but doctors did not know why – and therefore how to prevent it – until now ▫@sarahbooth_14 #frontpagestoday #Australia @theheraldsun 🇦🇺
Image from 𝙵𝚛𝚘𝚗𝚝 𝙿𝚊𝚐𝚎𝚜 𝚃𝚘𝚍𝚊𝚢 📰 (@ukpapers)
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Viruses, OTT cleanliness, genetics … all these have been linked to a higher chance of having #asthma. Now, @Benjmarsland has led research isolated the molecule IPA: when subjected to antibiotic onslaught, IPA disappears from the airways, taking with it valuable protection against asthma. Here’s Ben being interviewed in the lab with reporters from @7NewsMelbourne and @10NewsFirstMelb
Image from Translational Medicine at Monash University (@MonashSTM)
Image from Translational Medicine at Monash University (@MonashSTM)
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Microbiome derived indole-3-propionic acid prevents long-lasting mitochondrial damage in airway epithelial cells & hyperresponsiveness to allergen challenge, reducing allergic inflammation in adulthood @ImmunityCP @BenJMarsland @TomaszWypych8 @OPerdijk cell.com/immunity/fulltext/S…
Image from Waggoner Lab (@LabWaggoner)
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Incredibly proud to showcase our work published today in @ImmunityCP! Our findings reveal that the early-life gut microbiota produces metabolites with the potential to prime the airway epithelium and prevent allergic inflammation in adulthood. cell.com/immunity/abstract/S…
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#GutMicrobiome #Metabolomics #Antibiotics #CellMetabolism #AllergyResearch #ImmunityJournal #CellPress #MicrobiomeResearch #Immunology
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Olaf Perdijk retweeted
Immunity (@ImmunityCP) profile picture
Immunity@ImmunityCP15 Jul 2024
Online now: Antibiotic-driven dysbiosis in early life disrupts indole-3-propionic acid production and exacerbates allergic airway inflammation in adulthood dlvr.it/T9csJ3
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