Jason Padgett retweeted
Very proud of the impact of all our work using AI to accelerate science and medicine for the benefit of society.
Today we have set out how we’re building AI to accelerate science and improve people’s lives. Just some examples in the last week or so:
- Mapped all 9B possible single letter genetic changes across the human genome with AlphaGenome Atlas and made it openly available to researchers.
- Billions of decisions depend on weather predictions so we introduced WeatherNext 3, our most accurate and capable global weather AI model to date.
- We published AI & Economy ATLAS, a comprehensive open-access look at how people are using AI globally.
- AI has enabled extraordinary advances in language translation. Today our services are available in nearly 300 languages, spoken by 7B people
We’re focusing our efforts on four key areas: health, natural disaster and weather resilience, learning, and economic opportunity. blog.google/innovation-and-a…
President Trump calls Jensen mid-interview at the All-In Summit to say AI taking over the world is a hoax
Jensen: "Mr. President? I've got to tell you something. If it wasn't because of you calling, I would... I'm on stage with the besties."
Trump: "You see, the great thing about life is that Jensen can develop the most complex computer chip in the world that nobody can copy for 10 years, but he can't figure out how to put me on speaker."
"So, the AI, it's almost a conspiracy, and the happiest group is China, they're very happy."
"I'm telling you, it's all a hoax. The data centers are great and they make people wealthy and they make states wealthy and it's the oil of the next 20, 25 years. It's bigger than the Internet."
"The robots are not going to be taking over the world and that's not going to happen. The AI will not be taking over the rest of the world. The whole thing is a hoax."
"Now, with that, we have to be a little bit careful, but that doesn't mean we're going to stop an industry. So I'm with you all the way."
needless to say but if you have any API keys, eth wallet keys, user credentials, etc hanging out on the open internet in pastebins, GitHubs, etc now is the time to take it down before the tireless eagle eyes of a million models come looking
Jason Padgett retweeted
Still in beta, Polymarket already has best-in-class liquidity across virtually every category: pregame, futures, even in-play tennis. The depth is honestly absurd.
Deposit $20, get free $50 with my code DOV50
Try trading on tonight’s game 👇
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Jason Padgett retweeted
a masterclass in coding agents from the head of anthropic.
there’s still a tonne of leverage in knowing how to use these systems optimally and this is the best i’ve seen.
make sure to bookmark so you can watch again and again chat
Replying to @UnredactedDaily @AutismCapital
Neither. It's a formalization of his influence. The "AI & Crypto Czar" was an informal, part-time advisory title. Co-chairing PCAST (a key White House science/tech council) gives structured leadership on AI and emerging tech policy recommendations to the President—aligning perfectly with his expertise. Sacks called the appointment an honor.
Bill Gurley just identified the only career advantage that AI cannot commoditize.
It isn’t talent. It isn’t your degree. It isn’t your network.
Gurley: “The thing that will differentiate you more in your career than anything else is to be the most hyper curious person that’s trying to do this thing.”
For centuries, knowledge was gatekept. Elite institutions. Expensive mentors. Geographic luck.
The information existed but access to it was the moat.
That moat is gone.
Gurley: “You have no excuse not to be the most knowledgeable person, because the information’s all out there.”
Every question you can formulate now has an answer available instantly.
Every industry. Every domain. Every skill you want to acquire.
The playing field didn’t just level. It inverted.
The people who used to win by controlling access to information now compete against anyone willing to ask better questions.
Gurley: “I can’t make you the most talented person in your company or your field.”
Talent is genetic. It’s luck. It’s the variable you cannot control.
But knowledge is a choice. And curiosity is a compounding asset.
Gurley: “If you are the most curious person that’s constantly learning in your field, you will do extremely well.”
This was always true. What changed is the multiplier.
Gurley: “That advantage is put on steroids with these AI tools.”
A relentlessly curious person with access to all human knowledge and the ability to interrogate it in real time doesn’t just outlearn their peers.
They outlearn entire institutions.
The gap between the curious and the incurious was always there.
AI just made it insurmountable.
Jason Padgett retweeted
We made ChatGPT pretty restrictive to make sure we were being careful with mental health issues. We realize this made it less useful/enjoyable to many users who had no mental health problems, but given the seriousness of the issue we wanted to get this right.
Now that we have been able to mitigate the serious mental health issues and have new tools, we are going to be able to safely relax the restrictions in most cases.
In a few weeks, we plan to put out a new version of ChatGPT that allows people to have a personality that behaves more like what people liked about 4o (we hope it will be better!). If you want your ChatGPT to respond in a very human-like way, or use a ton of emoji, or act like a friend, ChatGPT should do it (but only if you want it, not because we are usage-maxxing).
In December, as we roll out age-gating more fully and as part of our “treat adult users like adults” principle, we will allow even more, like erotica for verified adults.
Jason Padgett retweeted

Mr Patel 🕉️@Patelindianlion13 Oct 2025
South Asia
South AsiaConnected via South Asia Android AppAccount-level information, not a live location or per-post device.
Replying to @JDVance
Jason Padgett retweeted
NEW: OpenAI gpt-oss models just dropped!
Two open-weight models:
- gpt-oss-120b
- gpt-oss-20b
> Full chain-of-thought available
> custom reasoning effort
> agentic capabilities
Apache 2.0 License
Here is all you need to know:
Jason Padgett retweeted

Elon Musk@elonmusk4 Aug 2025
United States!
United StatesConnected via United States App StoreLocation may be affected by a proxy or VPN.Account-level information, not a live location or per-post device.
Same
Jason Padgett retweeted
Think AI is making coding obsolete? Think again.
@kodewithklossy says coding builds confidence, problem-solving, and real-world career skills far beyond tech.
Tune into their inspiring conversation. mck.co/40VZmc6
Jason Padgett retweeted
Thinking Machines Lab exists to empower humanity through advancing collaborative general intelligence.
We're building multimodal AI that works with how you naturally interact with the world - through conversation, through sight, through the messy way we collaborate. We're excited that in the next couple months we’ll be able to share our first product, which will include a significant open source component and be useful for researchers and startups developing custom models. Soon, we’ll also share our best science to help the research community better understand frontier AI systems.
To accelerate our progress, we’re happy to confirm that we’ve raised $2B led by a16z with participation from NVIDIA, Accel, ServiceNow, CISCO, AMD, Jane Street and more who share our mission.
We’re always looking for extraordinary talent that learns by doing, turning research into useful things. We believe AI should serve as an extension of individual agency and, in the spirit of freedom, be distributed as widely and equitably as possible. We hope this vision resonates with those who share our commitment to advancing the field. If so, join us. thinkingmachines.paperform.c…
Jason Padgett retweeted

Andrej Karpathy@karpathy7 Apr 2025
United States
United StatesConnected via United States App StoreAccount-level information, not a live location or per-post device.
Jason Padgett retweeted
change of plans: we are going to release o3 and o4-mini after all, probably in a couple of weeks, and then do GPT-5 in a few months.
there are a bunch of reasons for this, but the most exciting one is that we are going to be able to make GPT-5 much better than we originally though. we also found it harder than we thought it was going to be to smoothly integrate everything. and we want to make sure we have enough capacity to support what we expect to be unprecedented demand.
Jason Padgett retweeted
Every new technology wave causes the previous ones to be reinterpreted as stepping stones. For example:
Personal Computer - Mainframe shrunk down so everyone can have one.
Internet - Now we finally have a bunch of things we can do on a PC.
Social - The real point of getting on the internet was to interact with other people.
Mobile - Actually the PC wasn’t that “personal.” The phone is the real personal computer.
AI - The reason we gave a computer ubiquitous access was to let it solve problems for us.
AI is the biggest wave yet.
Jason Padgett retweeted
"This is the year that AI gets better than humans at programming forever. And there's no going back."
OpenAI CPO Kevin Weil highlights the rapid improvement of AI models in competitive coding, predicting one will reach the number 1 spot in 2025.
He says AI surpassing humans in software is a "democratizing effect" and "you can create anything you want."


























