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🧠 This study in @CellCellPress found that receptor protein tyrosine phosphatase sigma is the host factor mediating #TetanusNeurotoxin trafficking into the #CNS! Congratulations to first authors Pengsheng Chen and Huan Wang, and their team! #OpenAccess🔗 bit.ly/4zyZu05

Researchers including Zhi Geng, Cheng Yuan, and Zeying Yua integrated multi-omics bioinformatics analyses with in vitro and in vivo functional experiments to investigate the role and mechanism of nucleoporin 35 (NUP35) in #glioblastoma glycolytic reprogramming. 🧠 Learn more: bit.ly/47iAMFh

Gabriel Said, Adelino Sanchez Ramos da Silva, and Guilherme da Silva Rodrigues examine evidence connecting exercise, DNA methylation, and Alzheimer's disease (AD), with emphasis on AD-related loci and on the possible intergenerational implications of parental exercise. 🏃 Learn more: bit.ly/3W7FvXQ #OpenAccess

This @NatureGenet study reports a single-cell atlas of alternative polyadenylation of the aged human brain 🧠 across 2 million cells from 379 human postmortem brains across individuals with and without #AlzheimersDisease. Don't miss it: go.nature.com/3Wh7hRI

🚨 A new study published in Advanced Science (@AdvPortfolio) uses 3D bioprinted-spheroids to assess blood–brain–tumor barrier penetration by anticancer drugs and their effects on #glioblastoma. 📑 Read the #OpenAccess article: bit.ly/4rOm2ap

🧠 Read this #OpenAccess review examining midbrain organoid-based #ParkinsonsDisease modeling through a concept-driven lens: bit.ly/3VjmOAl

Limonin ameliorates hyperuricemia-induced cognitive impairments, attenuates neuropathological alterations, modulates microglial polarization, and rescues neuronal apoptosis by targeting the HIF-1 pathway. Read the study: bit.ly/4AQuV7J Led by researchers at Southern Medical University and affiliated institutions. #CognitiveImpairment #Neuroinflammation

In a mouse model of ischemic stroke, a novel multifunctional nanoplatform (RM@HPAN) targeted ischemic brain regions, reduced infarct volume from 29.4% to 3.8%, improved neurological scores, and suppressed oxidative stress and inflammation. Read the study: bit.ly/4hm2C9l Led by first author Shaofa Li and corresponding authors Lanqing Meng and Tong Li. #StrokeResearch #Nanomedicine #Neuroscience

Results from a new study in @Dev_Cell provide evidence that species-specific regulation of proteasome-mediated proteolysis influences the timing of neural development and suggest that evolutionary tuning of proteasomal activity contributes to differences in embryonic developmental pace. Read more about the findings here📕 : bit.ly/4y8FroY

New study in @CellPressNews: research findings unveil a mechanism linking cancer metabolism with cancer neuroscience and leverage human genetics to nominate gluanidinoacetate synthesis as a target in #gliomas. Read more here: bit.ly/4yibjI1 #CancerResearch #Neuroscience

Findings from a new @NeuroCellPress study define inhibitory input as a suppressive component of the #glioma ecosystem and suggest that strengthening inhibitory tone may offer a therapeutic strategy. Read more here📕: bit.ly/4hzcD2W

🚨 New study in @CellCellPress unveils a mechanism linking #cancer metabolism with cancer neuroscience and nominates guanidinoacetate synthesis as a treatment target in #gliomas! Read the full #OpenAccess article here: bit.ly/4yibjI1 🧠

A new study reveals a hypothalamic-brainstem circuit linking acute stress to feeding suppression and gastric dysfunction. Read the paper: bit.ly/4xrbPC4 Led by first author Dan Dai and corresponding authors Jinfei Ni and Shumin Duan at @FudanUniv and Zhejiang University. #Neuroscience #StressResponse

Scientists from @Stanford define the architecture of the mouse serotonergic projectome! 🤯 They show organization by functional relatedness rather than the physical proximity of targets. Published in @CellCellPress: bit.ly/4r8ua5r

.@US_FDA approved Enigma Biomedical's TAUKLARIFY™ for use in patients being evaluated for #Alzheimers! 🧠 Press release 👉 bwnews.pr/46fATAR

Scientists from @UofCalifornia and @Princeton developed a fluorescent bifunctional reporter that can track estrogen response dynamics in #neurons!🧠 Read more here 👉 bit.ly/4gNbZgR

Researchers have defined the spatial + molecular determinants of malignant synapses by analyzing intact human #glioblastoma specimens. They revealed enrichment of synapse-like structures and synapse-associated gene programs at the tumor–brain interface. 🔬go.nature.com/4ygm50R

Yale School of Medicine (@YaleMed) has received a grant of nearly $25 million from the Aligning Research to Impact Autism to map human brain development and investigate how and when autism diverges from typical development. 📰 bit.ly/4xzlGqh

A research team at Sun Yat-sen University Cancer Center developed an intracavitary RNA-delivery hydrogel that targets tumor–neuron synapses after #glioblastoma surgery, suppressing recurrence and extending survival in preclinical models. 🔓 #OpenAccess Learn more at @natBME: ▶️ go.nature.com/4ygm50R

Researchers alongside Dr. Jeffery Twiss at @UofSC showed that a REG3A–KHSRP signaling loop within injured #axons restricts nerve regeneration through localized protein synthesis, revealing a potential target for accelerating nerve repair. 📕 @ScienceAdvances 🔖 bit.ly/4yxMLdN