The NephroNet team is officially on our way to ASN 2026!
We're looking forward to seeing our friends, colleagues, and research partners for an incredible week of connecting, collaborating, and advancing kidney care.
📍 See you at Booth #361!
#ASN2026 #NephroNet #DenverBound
A new review proposes a paradigm shift—focusing on nephron preservation and lifetime prevention, not just short-term biomarkers. A multifaceted approach targeting both IgAN-specific mechanisms and maladaptive kidney responses may redefine management.
ow.ly/9jrL50XWXnA
We're just days away from ASN 2026, and we're looking forward to a week filled with great conversations, meaningful connections, and exciting advances in kidney care.
Make sure Booth #361 is on your list of stops. We can't wait to see everyone!
#ASN2026 #NephroNet #KidneyCare
💜 Lupus nephritis affects up to 60% of SLE patients and remains a leading cause of kidney failure.
New therapies target immune pathways — but early diagnosis & coordinated care are key to preserving kidney function.
#Lupus #Nephrology #AutoimmuneDisease
pubmed.ncbi.nlm.nih.gov/4099…
ASN 2026 is almost here! What are YOU most excited about — groundbreaking research, new treatments, clinical trial updates, or reconnecting with colleagues?
We'd love to hear what you're looking forward to most! Drop a comment below.
#ASN2026 #NephroNet #KidneyResearch
We're excited to be heading to ASN 2026 and can't wait to reconnect with familiar faces, make new connections, and share what we've been working on!
📍 Stop by Booth #361 to say hello. We'd love to see you!
#ASN2026 #NephroNet #KidneyResearch #Denver2026
🧠 Nanoparticles that “teach” immune cells tolerance.
Cationic lipid–modified PEG-PLGA nanoparticles (CLAN) deliver dual siRNAs to dendritic cells, reducing T-cell inflammation in MS models.
💡 New path to reprogram immunity.
#Nanomedicine #Immunotherapy
pubmed.ncbi.nlm.nih.gov/4112…
In Jakarta, 1 in 7 adults with diabetes or hypertension already has CKD.
📉 eGFR declines ~4.7 mL/min/year.
⚠️ 49% face moderate–very high risk despite “normal” kidney function.
Screening early saves kidneys.
#CKD #Nephrology #Diabetes #Hypertension
pubmed.ncbi.nlm.nih.gov/4112…
⚠️ In Type 1 diabetes, overweight doubles CAD risk.
📊 J-DREAMS registry: 8.9% CAD in overweight vs. 3.4% in non-overweight adults.
Early weight control = stronger heart & kidney protection.
#Type1Diabetes #CardiovascularHealth #Obesity #DiabetesResearch
pubmed.ncbi.nlm.nih.gov/4112…
In Type 2 diabetes, 🩸
⬇️ Adropin levels + ⬆️ miR-21 expression = endothelial dysfunction.
These markers may predict vascular complications early — from nephropathy to neuropathy.
#Diabetes #CardiometabolicHealth #EndothelialFunction #miR21
pubmed.ncbi.nlm.nih.gov/4112…
Higher Triglyceride-Glucose (TyG) index = higher kidney risk ⚠️
In 9,661 adults, those in the top TyG quartile had a 75% higher chance of reduced eGFR.
💡 Lipid + glucose imbalance may predict kidney decline early.
#Nephrology #CKD #TyGIndex #PublicHealth
pubmed.ncbi.nlm.nih.gov/4112…
Blocking BAFF reduced total antibodies but didn’t stop abnormal IgA production in a murine IgAN model.
🧬 Suggests BAFF isn’t central to generating nephritogenic IgA.
➡️ IgAN therapy may require more targeted immune modulation.
#IgAN #Nephrology
pubmed.ncbi.nlm.nih.gov/4109…
Autoimmune glomerulonephritis = shared injury pathways 🔬
Complement, IL-17/IL-23, Fc receptors & interferon drive renal damage across lupus, IgA, & ANCA diseases. 🧩 Biopsy + multiomics may guide personalized therapy.
#Nephrology #AutoimmuneDisease #GN
pubmed.ncbi.nlm.nih.gov/4113…
📈 In IgA nephropathy, a high Cholesterol-HDL-Glucose (CHG) index > 5.29 predicts poorer kidney survival.
⚠️ Patients showed an 84% greater risk of renal decline.
Metabolic imbalance = worse renal outcomes.
#IgAN #Nephrology #MetabolicSyndrome
pubmed.ncbi.nlm.nih.gov/4110…
In IgA nephropathy, a higher neutrophil-to-lymphocyte ratio (NLR) predicts early kidney decline.
🩸 Inflammation marker tied to lower eGFR & worse clinical profile.
📊 NLR could serve as a simple risk tool for IgAN progression.
#IgAN #Nephrology #eGFR
pubmed.ncbi.nlm.nih.gov/4113…
A new multi-modality ultrasound model integrates grayscale, color Doppler & SWE to assess renal fibrosis in CKD.
🎯 AUC = 0.88
💡 Non-invasive, accurate, & ready for personalized kidney care.
#CKD #Radiomics #Ultrasound #Nephrology #MedicalResearch
pubmed.ncbi.nlm.nih.gov/4113…
High glucose triggers O-GlcNAcylation of ACSL4, driving ferroptosis in kidney cells 🧬
Knocking down OGT protected against renal damage in diabetic nephropathy models.
🔍 A new path toward targeted kidney protection.
#Nephrology #KidneyHealth #Ferroptosis
pubmed.ncbi.nlm.nih.gov/4113…
🧠 New study: Transdermal GFR detects AKI hours earlier than creatinine in cirrhotic mice — with no tubular injury.
⚡ Non-invasive skin sensor = faster, more sensitive kidney monitoring.
#AKI #Nephrology #BiomedicalInnovation #LiverDisease
pubmed.ncbi.nlm.nih.gov/4113…
🩺 New editorial in Br J Hosp Med:
“Reducing Therapeutic Nihilism in Chronic Kidney Disease.”
CKD deserves proactive, hopeful management — not resignation.
Empower patients. Intervene early. Treat boldly.
#Nephrology #KidneyHealth #CKD #ClinicalCare
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