Clinical Assistant Professor @UCalgary + @LibinInstitute. Echo / Prevention / Sports

Calgary, Alberta
Joined December 2017
Nathan Leader retweeted
This is a big bust, folks The first large scale (N>8000 participants) for lowering Lp(a) did not meet its primary endpoint for reducing adverse cardiovascular outcomes (vs placebo) novartis.com/news/media-rele…
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Clinical Considerations for the Care of the Tactical Athlete With Cardiovascular Abnormalities: A Scientific Statement From the American College of Cardiology and the American Heart Association sciencedirect.com/science/ar… #CVD #tacticalathlete #Sportscardiology
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Nathan Leader retweeted
Time-dependent outcomes in myocarditis and inflammatory #cardiomyopathy patients treated with the IL-1 receptor antagonist #Anakinra academic.oup.com/eurjhf/adva… #EJHF @HanCardiomd @AmrAbdin10 @GiuseppeGalati_
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Nathan Leader retweeted
A recent review in @NEJM discusses sudden cardiac arrest management in athletes. Read the Key Points and a comment from Deputy Editor Ann Cheung, MD, MBA, MS: nej.md/4a3IjtR #cardiology
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Nathan Leader retweeted
New advances in risk assessment and management are shaping updates across international cholesterol guidelines. This forecast highlights shifts in interpretation, thresholds, and treatment strategies to better prevent ASCVD worldwide. 🔗 ow.ly/185V50Y6E1G #Cholesterol
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Nathan Leader retweeted
🔴Myocarditis & look-alikes: when the diagnosis matters @Heart_BMJ #Cardiology #CardioEd #Myocarditis
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Nathan Leader retweeted
Standardization of Baseline and Provocative Invasive Hemodynamic Protocols for the Evaluation of #HeartFailure and Pulmonary Hypertension: A Scientific Statement From the @AHAScience ahajournals.org/doi/10.1161/… @CircHF #HFpEF
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Aspirin or P2Y12 inhibitor monotherapy in atherosclerotic cardiovascular disease? Read this State-of-the-Art review in #EHJ 👉 ow.ly/Ze0p50XqmPK @RoccoMontone @ehj_ed
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OCEAN trial: For AF patients with ≥1 risk factor post-catheter ablation, low-dose rivaroxaban showed similar rates of stroke/systemic embolism and major bleeding at 3 years compared to aspirin. #AHA25 View the slides here: clinicaltrialresults.org/wp-…
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Nathan Leader retweeted
What a strange conclusion for this article. I'd edit it to: Among older nursing home residents with frailty who were receiving treatment with antihypertensive agents and had a systolic blood pressure below 130 mm Hg, an antihypertensive treatment step-down strategy was safe. H/T @AndrewFoy82 Reduction of Antihypertensive Treatment in Nursing Home Residents | New England Journal of Medicine nejm.org/doi/full/10.1056/NE…
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Nathan Leader retweeted
Early Surgery for Asymptomatic Severe MR @SahminL ahajournals.org/doi/full/10.…
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You don't need to be a competitive athlete to have an athlete's heart. Regular exercise—especially over 5 hours weekly—reshapes the heart, boosting health and performance. bit.ly/3Gor9Lp
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🗞️ Impact of genotype–phenotype associations on prognosis in #DilatedCardiomyopathy @ESC_Journals @GiuseppeGalati_ @AmrAbdin10 @HanCardiomd bit.ly/4nuVZBN
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Pre-participation screening in competitive athletes in Italy: an analysis of real-world practice from a large database academic.oup.com/eurjpc/adva… #preparticipationscreening #ECG #Sportscardiology #athlete
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#ESCCongressVisuals from Hot Line 3👇 Given the progress made in the management of acute myocardial infarctions, it is important to understand whether beta blockers still have a role in those with mildly reduced EF. Will the REBOOT trial demonstrate a reduction in the rates of death, reinfarction or hospital admission for heart failure? 👇 The large combined Danish (DANBLOCK) and Norwegian (BETAMI) randomised beta-blocker trials provide evidence on the use of beta blockers post-MI in patients with preserved EF. Will there be a reduction in a composite of recurrent MI, all cause mortality, malignant VT, cardiac arrest and HF? 👇 REBOOT/BETAMI/DANBLOCK/CAPITAL-RCT: This large meta-analysis provides the largest dataset to date to determine the efficacy of beta blockers in improving outcomes post-MI in those with mildly reduced EF. 👇 Will noninvasive assessment permit identification of high risk post-MI patients with preserved LV function? How will ICD use post-MI change after the results are shared? Will this trial impact guidelines? 👇 #ESCCongress
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#ESCCongressVisuals from Hot Line 5👇 DANCANVAS 2 attempts to reduce social inequality in cardiovascular health by performing an interventional screening trial on how best to decrease cardiovascular disease amongst individuals of low social status. 👇 PREVENT-MINS is a multicentre, superiority randomized controlled trial of ivabradine versus placebo. The primary objective is to determine the impact of ivabradine on the risk of MI in patients 30 days after noncardiac surgery 👇 The ABC-AF study evaluates whether a personalized treatment recommendation strategy-guided by the biomarkers improves outcomes in AF. How generalizable is this study? 👇 Patients with acute VTE in the setting of transient provoking factors are treated with short-term anticoagulation. However, the risk of recurrence may increase if there are enduring risk factors. Will patients receiving extended treatment of apixaban reduce recurrence rates? HI-PRO is a single-center, double-blind randomized trial that answers this question. 👇 #ESCCongress #ESCCongressVisuals
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Nathan Leader retweeted
WITHDRAW-AF RCT 📌 In👫w/ presumed AF-induced #cardiomyopathy & normalized #LVEF after SR restoration 👉 withdrawal of #HF therapy is not assoc w/ LVEF ⬇️ again in 90% of👫in the following 6-m #EPeeps #afib #HeartFailure #CardioTwitter #MedTwitter @DrMarthaGulati @JagSinghMD
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Nathan Leader retweeted
Lipid management remains key in preventing #ASCVD. While statins are foundational, nonstatin therapies are expanding fast. This expert panel reviews current international recommendations regarding lipid management. jacc.org/doi/10.1016/j.jacad… #cvLipids #JACCAdvances
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