@NatKingScience

Pericytologist and neuroscientist. Currently researching the role of vascular dysfunction in Alzheimers Disease and Multiple Sclerosis. 🧠🧪🥼

 Hobart, Tasmania
researchgate.net/profile/Natalie-King-21
Joined October 2020
  • Tweets46
  • Following579
  • Followers430
4Media
The primary cells of the neurovascular unit: endothelial cells🔵, pericytes🦑 and astrocytes🟢 🦋
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Great to see Tram's paper online showing that rTMS increased interneuron activity following demyelination and increased remyelination by new and surviving oligodendrocytes. Thanks to coauthors including @DrCarlieCullen , @AlastairFortune , @LauraReale12 , @Tomlewis2310 .
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Perivascular macrophages (LYVE1🟣) on blood vessels (CD31🔵) clearing out the brain 🧠 #FluorescenceFriday #neuroscience #immunohistochemistry
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The Preventing Dementia MOOC starts on the 14th of May. A free online course that examines the evidence for dementia risk reduction. Join an international audience in learning about this important public health issue. mooc.utas.edu.au/course/2018…

Preventing Dementia (2026)

Join thousands worldwide in the Preventing Dementia MOOC, created by the Wicking Dementia Centre. This free, flexible course explores the latest evidence on dementia risk reduction, covering lifest...

mooc.utas.edu.au
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Check out our new work on how microglia interact with the vasculature through astrocyte end feet using the @AllenInstitute #MICrONS cortical mm^3 dataset! Had a great time working with @Gazz4_Science, @BradASutherland and @SorenGrubb to produce this work!
Søren Grubb@SorenGrubb
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1/ 🔥 Exciting findings from our collaboration between @UTAS_, @SeattleChildrens, and @uni_copenhagen! We've discovered a new way #microglia interact with 🧠 vasculature, which could reshape our understanding of their role in #brain health and disease. 🧵 biorxiv.org/content/10.1101/…
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Our latest publication was just released in Stem Cell Research and Therapy, showing gene expression and functional differences between neural crest and mesoderm iPSC-derived pericytes (iPericytes). Check it out here: doi.org/10.1186/s13287-024-0…

Induced pluripotent stem cell derived pericytes respond to mediators of proliferation and contrac...

Stem Cell Research & Therapy - Pericytes are multifunctional contractile cells that reside on capillaries. Pericytes are critical regulators of cerebral blood flow and blood–brain barrier...

link.springer.com
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Thanks to co-authors @BradASutherland @jomaree @DrLachlanSBrown @AlastairFortune @LabGlial @nickomatics @FletcherJL @Jake_Cashion_ and twitterless co-authors Jana Talbot, Alice Pebay, Alex Hewitt, Gary Morris and Tony Cook.
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We invite applications for a postdoctoral position with the Glial Research Team in Hobart, Australia. Please apply online by following this link. careers.utas.edu.au/en/job/4…
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We're hiring! Come and work with use on understanding the cellular mechanisms of brain dysfunction in MS! careers.utas.edu.au/en/job/4… with @LabGlial and @nickomatics
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If you are interested in undertaking a PhD us please follow this link for more information utas.edu.au/research/degrees…
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We're recruiting! Interested in how #mitochondria and #astrocytes regulate neuroinflammatory responses during demyelination? Our group is looking for a PhD student: shorturl.at/firvM Project uses transgenic mice, confocal microscopy and transcriptomics. Get in touch!
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Natalie King retweeted
Dr Yasmine Doust@y_doust
5 Dec 2023
Check out some of this work in GLIA onlinelibrary.wiley.com/doi/…

Microglia directly associate with pericytes in the central nervous system

Microglia dynamically associate with pericytes in the brain. Microglia can contact the basement membrane covering pericytes. The proportion of microglia associated with pericytes and capillaries is...

onlinelibrary.wiley.com
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Natalie King retweeted
Dr Yasmine Doust@y_doust
6 Dec 2023
An exciting talk by @AlastairFortune about #MultipleSclerosis-associated gene variants @AusNeuroSoc 2023 in #Brisbane with some beautiful IHC images! @UTAS_ @LabGlial @ANS_Students
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Natalie King retweeted
Dr Yasmine Doust@y_doust
5 Dec 2023
Fabulous talk by @BradASutherland at @AusNeuroSoc 2023 in #Brisbane about #pericytes and #microglia in health and disease. @UTAS_ @UTAS_MPH
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📢 Exciting news - my latest preprint exploring the impacts of pericyte ablation on behaviour and brain health is out! 🧠🩸🐭 biorxiv.org/content/10.1101/… @BradASutherland @LabGlial Pericytes 🟣 Vessels 🟢 #pericytes #neuroscience (1/3)
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Sometimes #pericyte cell culture can get #spooky. Is this #perinormal activity? #HappyHalloween 🎃💀 perivascular.org/our-team @BradASutherland @NatKingScience @jomaree @Jake_Cashion_
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We are excited to present our most recent preprint, outlining gene expression differences and functionality of mesoderm and neural crest iPSC-derived pericytes (iPericytes) in comparison to human brain vascular pericytes (HBVPs) biorxiv.org/content/10.1101/… (1/3)

Induced pluripotent stem cell derived pericytes respond to endogenous mediators of proliferation...

Background Pericytes are multifunctional contractile cells that reside on capillaries. Pericytes are critical regulators of cerebral blood flow and blood-brain barrier function, and pericyte dysfun...

biorxiv.org
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Thanks to co-authors @BradASutherland @jomaree @DrLachlanSBrown @AlastairFortune @LabGlial @nickomatics @FletcherJL @Jake_Cashion_ and twitter-less co-authors Jana Talbot, Alice Pebay, Alex Hewitt, Gary Morris and Anthony Cook (2/3)
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We found substantial differences in gene expression between iPericytes of different lineages. We also found iPericytes proliferate in response to PDGF-BB and respond to vasoactive mediators endothelin-1 and adenosine, with some lineage specific differences in their response (3/3)
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Join us next Friday for a workshop facilitated by @BradASutherland's Perivascular Research Group! This workshop aims to provide insight in successfully developing an engaging and scientific literate presentation that will ‘WOW’ the audience. Check your email for a zoom link!
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