Biologist, Ph.D. & gamer. TFs & ncDNA lover. PostDoc at the Rabinovitch Lab @stanfordCVI. Cloning, iPSCs and chromatin to understand penetrance in #PAH.
Stanford, CA
Joined June 2011
- Tweets1.2K
- Following467
- Followers391
- Likes2.7K
Mauro Lago-Docampo retweeted
I am super excited to share our paper in the AJRCCM! @ATSBlueEditor. We have evidence to suggest that, in addition to TBX4 and SOX17, developmental transcription factors like FOXF1 may play a role in the development of adult lung vascular disease!
🔗 doi.org/10.1093/ajrccm/aamag…
-Why is this confocal always broken in some way?
*checks the reservation log*
-Oh, almost 40 hours of use for this week from a single lab.
Mauro Lago-Docampo retweeted
Inspired by Gibson cloning, we describe prime assembly, now published, for in cellulo targeted integration of gene-sized DNA fragments using prime editing. nature.com/articles/s41586-0…
With the amount of times the CA DMV made me do their online test to renew the license I must be the safest driver in California.
Mauro Lago-Docampo retweeted
Today in @NatureBiotech we report OptiPrime, a mechanism-based machine learning model for predicting prime editing (PE) efficiencies and suggesting pegRNAs to achieve a user-specified edit. OptiPrime incorporates biochemical knowledge about PE into its mathematical structure, enabling training on ~300,000 PE efficiencies collected using 40 experimental conditions in multiple labs, and outcome predictions of PE variants such as twin prime editing not used in its training. OptiPrime enabled the rapid identification of efficient PE strategies across a variety of applications in vitro and in vivo, and could outperform months or years of manual experimental optimization.
Try out OptiPrime here: optipri.me
PDF: drive.google.com/file/d/13JZ…
1/15
Mauro Lago-Docampo retweeted
📢 "Ciencia sen mans" — o noso novo artigo de opinión, publicado hoxe en @GC_GCiencia! Falamos do problema estrutural do financiamento competitivo en España, con datos, e propoñemos cambios concretos. #Ciencia #Investigación #FinanciamentoDaCiencia
Pódese facer ciencia competitiva con menos de 500.000 euros ao ano? A pregunta que trata de resolver nesta tribuna a xunta de representantes de @InvestiGal.
gciencia.com/tribuna/ciencia…
Mauro Lago-Docampo retweeted
Join the next Living Legends in PH webinar 🫁
Nick Morrell has helped shape PH research for decades – from advancing our understanding of bone morphogenetic protein biology to developing new approaches to treatment.
In this special session, he’ll share the science, stories, and experiences behind his career, with discussion led by Gregory Elliott and Shreya Sangam.
Living Legends: Nick Morrell, Cambridge Heart and Lung Research Institute
📅 20 August 2026
🕟 16:30 – 18:00 BST
Hear personal reflections from one of the field’s leading figures, explore key developments in PH, and join the live discussion.
➡️ Register now: pvrinstitute.org/learning-hu…
Mauro Lago-Docampo retweeted
For biologists using Claude Science, here is Motif, an AI-native molecular biology workbench plugin. Now, you don't need to leave Claude Science to view and operate on your sequences.
Motif gives the full power of Claude to your upstream mol bio workflows, such as asking Claude to: 1) fetch the genes in a target pathway and annotate them, 2) perform and view multiple sequence alignments using your preferred alignment tool, 3) design and label CRISPR-Cas guide sequences, and much more.
Motif was built as part of the "Built with Claude: Life Sciences" hackathon, and is an MIT-licensed, open source plugin.
Also, Claude made this demo video using HeyGen's Hyperframes and Elevenlabs TTS.
Mauro Lago-Docampo retweeted
Excited to share that my PhD thesis work is now available as a preprint! shorturl.at/vgfzv This work represents a long but rewarding journey. Grateful to my PIs @MingxiaGu and @ZornLab, and all our collaborators for their help and guidance.
#organoids #NAMs #iPSCs
I will have to order more plasmids now
1320 para sobrevivir en USA es surrealista.
Una fantasía las dietas.
Científicos con las dietas para viajes de trabajo congeladas desde 2002: “Un año perdí 4.500 euros, ahora me limito” eldiario.es/sociedad/cientif…
Mauro Lago-Docampo retweeted
Fetal Bovine Serum is one of those products people try not to think about. It rests in the methods sections of Nature publications and in the hefty Quartzy bill associated with running a lab.
It has been the bedrock of our field since 1958, when Theodore Puck formalized it as the essential, undefined part of a universal media.
This is a good chance to meet my boss, Marlene has a gift to help you dissect extremely complicated questions into manageable experiments.
Don’t miss this seminar! She is an extremely good mentor (and tough when needed).
What can the history of PH teach us about its future?
Join us next week for the next Living Legends in PH: History & Personal Perspectives session.
Living Legend: Marlene Rabinovitch, Stanford University
📅 18 June 2026
🕓 16:00 – 17:30 BST
💻 Free and open to everyone
➡️ Register: pvrinstitute.org/learning-hu…
Mauro Lago-Docampo retweeted
Hallazgo vigués en el Instituto Pasteur de París: el biólogo Rubén González demuestra que los virus aceleran el envejecimiento farodevigo.es/gran-vigo/2026… a través de @Farodevigo
I was definitely not expecting that tweet to hit that hard.
I had to silence the tweet because it was distracting me too much lol, but I will try to reply slowly to whoever is left.
In January, I reviewed a Review for a crappy MDPI journal.
It was 100% AI, missing citations, etc. I sent a massive report, and the authors withdrew it.
Today, I see it published without a single change in another even crappier MDPI journal.