Updates and insight on the MS-STAT2 study from the team at UCL. A phase 3 clinical trial of high dose simvastatin for secondary progressive multiple sclerosis
London, England
Joined April 2019
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MS-STAT2 retweeted
Today the results of the MS-STAT2 trial were announced by Professor Jeremy Chataway at the ECTRIMS research conference in Copenhagen.
This trial tested simvastatin, commonly used to treat high cholesterol, in 964 people with secondary progressive MS. (1/6)
MS-STAT2 retweeted
Thank you @StuStepsUp+Marie for inspiring work @mssocietyuk @mscymru Ambassadors for people with #MS #AdvancedMS Check out chariotms.com #ChariotMS @QSMSCENTRE @MsStat2 @OctopusTrial @AttackMS_trial @the_MSBlog #MS @RachelHorne19 @themsguide @aid4disabled #NHS75 #GIG75
Recently retired nurse & general manager and MS ambassador @StuStepsUp talks candidly about his experience of working in the NHS with MS over the last 40 years and how demand has changed vastly over that time.
#NHS75 #GIG75
MS-STAT2 retweeted
Excellent @EANeurology #EAN2023 update on our expanded knowledge of #MS CNS compartmentalised inflammation and the exciting near future of BTK Inhibitors by Wallace Brownlee, Veronica Popescu and Martin König
@DrWBRO @VeroPopescu
MS-STAT2 retweeted
Great to be in Budapest for #EAN2023 discussing PIRA, compartmentalized CNS inflammation and BTK inhibitors with Veronica Popescu and Marton König @VeroPopescu @EANeurology
MS-STAT2 retweeted
What is MS progression? Our understanding of progress independent of disease activity (PIRA) has grown over the last 20 years, with clinical and real world studies confirming that once relapses are controlled with DMTs progression can still happen!
MS-STAT2 retweeted
An excellent overview of #SMOULDERINGMS - how we see progression independent of relapses #PIRA, what processes are involved and what #biomarkers will let us ultimately lead to individualized treatment!
MS-STAT2 retweeted
#BrainAtrophy and #CognitiveImpairment in #MS - Closely interlinked, and of great importance to PWMS. Cognitive impairment being associated with more care needs and worse quality of life - focus on slowing/stopping this is essential!
MS-STAT2 retweeted
#BigData in #MS - a great overview of the incorporation of all the -omics (genomic, metabolomics, proteomics, etc) towards novel understanding and treatments for #PMS #ProgressiveMS
MS-STAT2 retweeted
Higher serum neurofilament light chain (sNfL) is linked to more cognitive decline in MS. Data from the MS-STAT study (simvastatin vs. placebo in progressive MS) pubmed.ncbi.nlm.nih.gov/3594…
MS-STAT2 retweeted
Serum neurofilament light and MRI predictors of cognitive decline in patients with secondary progressive multiple sclerosis: Analysis from the MS-STAT randomised controlled trial - PubMed pubmed.ncbi.nlm.nih.gov/3594…
MS-STAT2 retweeted
Job alert: Clinical Research Fellow at UCL…an excellent opportunity for a neurology trainee with an interest in MS and research jobs.ac.uk/job/CQK730/clinic…
MS-STAT2 retweeted
It's #InternationalClinicalTrialsDay!🥼🔬
From trialling a promising drug to taking a survey at home - there are lots of different types of research you can take part in.
We asked people living with MS what it's like to take part in our research studies: mssoc.uk/3PD47jN
ALT Image shows chair user Glyn does leg strengthening exercises with others with MS
MS-STAT2 retweeted
Access to #siponimod for people with SPMS in England has been expanded to include those who are progressing on another DMT but inflammatory activity is suppressed. Great to be able to now offer this option to people with MS 👍🏻
MS-STAT2 retweeted
#StopMS #AttackMS #ChariotMS @MsStat2 and so much more - Congratulations @mssocietyuk for winning at the Charity Film Awards
⭐️Next up is the £20m-£50m People’s Choice Award⭐️
🥉Bronze is @VersusArthritis
🥈Silver is @PriorsCourt
🥇The winner is @MSSocietyUK Congratulations!
Watch the winning film: smileymovement.org/organisat…
#CharityFilmAwards #CFA22
MS-STAT2 retweeted
Lovely to celebrate the PhD with colleagues in person! Thank you to my wonderful supervisors and mentors @olgacicc @QSMSCENTRE @MsStat2 @jchataway
Fantastic to see so many of our students at UCL’s in-person graduation ceremonies!
Here’s @UCLBrainScience Faculty Dean Prof Alan Thompson celebrating with #UCLBrainiacs Rosa, Floriana, Sara & Anisha at one of today's ceremonies 🎓🎉
#UCLBrainiacsGrad #UCLGrad
MS-STAT2 retweeted
Today we are thrilled to launch the UK DRI Biomarker Factory (@UkdriL)! 🎉🥳
From the lab of Prof Henrik Zetterberg (UK DRI at UCL), the high-performance analytical platform will find new ways to detect & monitor neurodegenerative disease
🔎🩸🧠
👉bit.ly/3INwFm2
MS-STAT2 retweeted
Dr. @RosaCortese5 has presented "MRI and clinical features differentiate non-acute MOGAD from AQP4-NMOSD and RRMS: a @MAGNIMS multicenter study" Have a look at @ectrimscongress
MS-STAT2 retweeted
Dr Sarah Wright presenting results of her study on how best to follow-up CIS patients with normal MRI at onset #ECTRIMS2021 @QSMSCENTRE @UCLIoN
MS-STAT2 retweeted
Dr Madiha Shatila presenting her work on #PPMS diagnostic criteria. If #MS is one disease then why do we need separate diagnostic criteria for RR and PPMS? #ECTRIMS2021 @QSMSCENTRE @UCLIoN
