@MoskowitzLab

Our primary goal is to understand the molecular logic underlying biological processes including cardiac development and cardiac rhythm.

 University of Chicago, Chicago, IL
Joined August 2018
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Check out our recent publication describing the exciting work driven by Kohta Ikegami: Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria @Dev_Cell cell.com/developmental-cell/…

Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal...

Nuclear lamins bind heterochromatin domains at the nuclear periphery. Ikegami et al. now show that phosphorylated form of nuclear lamins bind to active enhancers in euchromatin in the nuclear...

cell.com
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Differentiation goddess @MJR_groove presenting her work on cardiac differentiation delay at the Cell Symposia: Transcription Regulation Conference this weekend! Other members of our lab @how_and_why_sci, @Sonja_Lazar, Ariel, and Kohta also gave posters on their work.
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Congratulations to Alex Guzzetta (@alex_guzzetta) and Jeff Steimle on successfully defending their theses! 🎉🎉
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#Weinstein2019
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@MJR_groove @alex_guzzetta @Sonja_Lazar
We are looking forward to the Weinstein Conference this week! @Weinstein2019 #Weinstein2019
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Congratulations to @Wenli25 and Brigitte on their recent publication! In collaboration with the Weber Lab, we establish a mechanism underlying the genetic basis for a Ca2+ dependent pathway in AF risk. @eLife elifesciences.org/articles/4…

A calcium transport mechanism for atrial fibrillation in Tbx5-mutant mice

TBX5-loss associated cardiomyocyte ectopy and atrial fibrillation is prevented by augmentation of SERCA2 activity, establishing a mechanism underlying the genetic basis for a Ca2+-dependent pathway...

elifesciences.org
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