Morphogenesis in development, disease, and evolution. Led by Amy Shyer & Alan Rodrigues @RockefellerUniv

The Rockefeller University
Joined May 2022
The latest CBF Dialogue: Beyond machines and feedback loops for a true science of life | Matteo Mossio youtube.com/watch?v=sd1xZ_qJ…
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The next CBF virtual seminar is tomorrow! Matteo Mossio will present "Moving beyond the clockwork universe: Developing theory for living systems" on July 7th, 10 am EDT rocku.zoom.us/j/98829413525?… For recordings of previous CBF seminars and dialogues: youtube.com/@ConceptualBiolo…
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Conceptual Biology Forum Dialogues: youtube.com/watch?v=buDvoFiV… In this video, Alan and Ruslan Medzhitov cover topics including: Why is the level between cells and tissues poorly understood? What are the implications for drug design, funding, and teaching? Is there a meaningful difference between structure and organization? What motivates this new way of thinking?
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Shyer/Rodrigues Laboratory of Morphogenesis retweeted
Have you heard yet about the Conceptual Biology Forum?! As the organizers Amy Shyer & Alan Rodrigues say, if you're not thinking conceptually, then you're just accepting the existing concepts without giving a possibility for new ones. youtube.com/@ConceptualBiolo… @MorphoLab_AS_AR
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Check out our new virtual seminar series called the Conceptual Biology Forum, aimed at creating a space for experimental biologists to consider and develop concepts for living systems. We host Zoom talks from philosophers, historians, and experimentalists. Join via Zoom to hear tomorrow's talk from Dr. Ruslan Medzhitov (Yale) entitled, "Cell Communities and Tissue Organization" Date: June 16th, 2026 Time: 10am – 11am EDT Zoom link: rocku.zoom.us/j/99940265457?… Meeting ID: 999 4026 5457 Passcode: 564924 Previous talk recordings here: youtube.com/@ConceptualBiolo…
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Big congrats from the Shyer/Rodrigues lab to lab alum @sichen_yang on becoming a Schmidt Science Fellow!
We are excited to announce our 2025 Schmidt Science Fellows! 32 early career researchers, nominated by the world’s leading research universities, who will take an interdisciplinary approach to advancing discovery schmidtsciencefellows.org/ne…
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Our recent piece: Transcending the hegemony of the molecular machine through an organic renewal of biology and biomedicine. Here, Alan covers the State of Science in biology and biomedicine, why it has stagnated, and where it needs to go. alanrrodrigues.substack.com/…
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3/4 We discuss that, while underrepresented, holistic biophysical thinking is not new and was apparent in the approach of two notable 20th century theorists of morphology, D’Arcy Thompson and Pere Alberch.
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4/4 Focusing on the supracellular scale, we articulate how holistic biophysical thinking provides an expanded view of three key concepts in biology (epigenetics, mechanism, and regulation).
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Shyer/Rodrigues Laboratory of Morphogenesis retweeted
Replying to @MBLScience
@MBLScience Embryology alumna Amy Shyer & Alan Rodriguez from @RockefellerUniv kick off the first afternoon session Amy puts forward a different way of thinking about morphogenesis not as a machine but as a consequence of reciprocal causality sciencedirect.com/science/ar… cell.com/cell/pdf/S0092-8674… Alan, in turn, describes experimental approaches to test this model science.org/doi/10.1126/scie… science.org/doi/10.1126/scie… #spemannmangold2024 @UniFreiburg
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Shyer/Rodrigues Laboratory of Morphogenesis retweeted
#spemannmangold2024 @MorphoLab_AS_AR beyond single cells & genes, moving our thoughts towards #emergent properties of cells ensembles w/ good experimental system. In many ways, Spemann’s organizer is an example of a ‘whole’ working together. For details: shorturl.at/tnrX9
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Our seminar at the Cambridge Morphogenesis Seminar Series is available online! Feel free to take a look if you are interested in attempts to transcend reductive machine thinking through an organic revival of morphogenesis. youtube.com/watch?app=deskto…
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Shyer/Rodrigues Laboratory of Morphogenesis retweeted
Great Day #2 at #EESMechanobiology with @_Priya_R @CampasLab @MorphoLab_AS_AR and many other great talks.
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Congrats to @karl_palmquist for winning the Weintraub Graduate Student Award! We were very fortunate to work with Karl and are immensely grateful for the conceptual openness and intellectual bravery he exhibited throughout his time in the lab.
A huge congratulations to the recipients of the 2024 @FredHutch @WeintraubAward! These twelve exceptional graduate students exemplify the bold, creative, and pioneering spirit embodied by Dr. Hal Weintraub: fredhutch.org/en/news/releas…
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Thank you @AMartinezArias and @Amro_Hussien for your interest and kind words!
Thank you for bringing this up to my attention, It is a very good discussion, probably the best I know of, on the topic of #SelfOrganization in the Developmental Biology
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In our new review, we confront how self-organizing systems blur the line between cause and effect through reciprocal causality! (1/4) sciencedirect.com/science/ar… #selforganization #causality #supracellular #morphogenesis
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3/For example: interacting components at a low length-scale give rise to complex patterns at a higher scale. At the same time, the self-organized order at the higher scale influences the low-level components, establishing a self-perpetuating system. New forms emerge.
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4/Simultaneous causal influence between separate entities—aka reciprocal causality—empowers self-organizing systems to create form. From this outlook, we review recent studies where self-organization at the supracellular scale drives creative processes during organ morphogenesis.
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