@Moooonflash

🇲🇫 🪆 IT business analyst + artist before 🦠 #LongCovid : #fibrosis #neuropathy #SFN #MCAS #MRGPRX2 SARS-COV-2 = persistent vascular virus

France
Joined May 2022
Antivirals (taken in first hours after infection or symptoms) are the only thing that can prevent #LongCovid . If false or not efficient paths are taken for the cure of Long Covid, we will forever be at risk of several cumulative #LongCovid
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Arrêts maladie.... Visualisation au Royaume Uni.
So, tell me, is the problem over yet, or still getting worse?
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Hong Kong Baptist University researchers review how natural killer cells shape brain disease, from clearing virus infected cells and autoreactive immune cells to driving inflammation. The key may be targeting the right NK cell subset. onlinelibrary.wiley.com/doi/…
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🚨 It’s finally out! The video that explains clearly what we believe is happening when infrared light hits the mitochondria. It’s worth the whole watch! How Infrared Light Actually Affects Your Mitochondria - Hypothesis youtu.be/ID5k4G3ogqM
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Long Covid POTS epidemic. Don't listen to the liars who say that it's a social media trend. It's hard cold clinical diagnoses:
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SARS-CoV-2 subtly disrupts the blood-brain barrier, potentially leading to unpredictable, far-reaching consequences.
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Decreased inflammation from GLP1 RAs leads to more stable plaques, myocardial remodeling, reduced cytokine storm, stronger gut barrier, and decreased immune hyperactivity in the brain and autoimmune disease. academic.oup.com/jcem/articl…
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Remember my post about red light increasing collagen synthesis or killing fibroblasts depending in dose?
The central point in our pre-print is Marcus Transfer Theory which shows why infrared light can both increase and decrease electron transfer: Watch it for yourself and don't depend on others to tell you what it says... youtu.be/ID5k4G3ogqM?si=Unel…
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📈 Reprise épidémique de #Covid19 en Angleterre également : forte hausse du taux de positivité (en partant de très bas), comme les années passées à la même période.
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People whose IFN-gamma started earlier shed ten to a hundred times less virus over the first ten days. True in the nose and in the mouth. It isn't whether the response arrives - almost everyone gets one. It's how many days early.
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In 88% of participants, virus appeared in the nose at least a day later than in the mouth or throat - 2.3 d later on average. The nose isn't the first doorway, as was long assumed. It's more like where the infection spreads to.
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There is a REASON China is using repurposed HIV drugs for Covid. Azvudine blows Paxlovid out of the water in every study. It protects the thymus when Paxlovid does not. Since it’s an old drug & won’t make billions of dollars, we are forbidden from accessing it.
Replying to @LauraMiers
As western LongCovid patients quietly swap stories about bloodwork that look like they have advanced AIDS, For the last year & a half or so, China has been giving HIV drugs to adults with Covid. Western countries have not, & the clock is ticking. scmp.com/news/china/science/…
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18 young, previously healthy people. Mild COVID, nobody hospitalized. Six months later, they're still dealing with brain fog, worse sleep, anxiety, low mood. On a test of inhibitory control they did just as well as controls. But their EEG told a different story about how their brains got there🧵
Neurocognitive Indices of Long COVID: Dysregulated Engagement of Inhibitory Control and Oscillatory Slowing 🚨Even after mild COVID, LongC0VID can leave a measurable brain signature. Interesting small USA study that needs your attention: ➡️~6 months later, young, otherwise healthy adults with PASC reported more brain fog, anxiety, depression and sleep problems, ➡️On an inhibitory Go/NoGo task their performance looked intact, but EEG did not, ➡️Neural indices showed altered cognitive-control engagement on both correct and error trials, less efficient responding, and a trend toward dysregulated co-oscillatory synchrony during errors, ➡️Altered neural indices of inhibitory control marginally correlated with spontaneous oscillatory slowing, potentially suggesting shared basic mechanisms, ➡️“The overall pattern of PASC symptoms, altered neural activity during inhibitory control, and oscillatory slowing, is indicative of the core neural dysfunction characterizing PASC”. ‼️So, LongC0VID here is not symptoms without a signal. It is a core neural dysfunction that behavioral tests miss and EEG detects. ‼️In layman terms: After even a mild COVID infection, some people keep the fog, the bad sleep, and the low mood. Everyday tests may say nothing is wrong. The brain however can be working less efficiently, especially when it has to stop itself, stay on task, or recover from a mistake, and to be honest, I'm seeing a lot of this around me! #AvoidSars2 #AvoidReinfections mdpi.com/2673-4087/7/5/105 mdpi.com/2673-4087/7/5/105/p…
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A few scientific facts. Covid is a multi-system disease with sequelae across all organs. SARS-CoV-2 didn't not disappear; actually a new variant is on the rise in multiple countries. It's not endemic. SARS-CoV-2 is airborne, namely it spreads in the air a bit like cigarette smoke
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I feel sorry for the people who believe they & their families are getting Covid & walking away unscathed. People aren’t clearing this virus. There is no funding left to study it. The long-term consequences are already appearing, & will become more obvious over time, in everyone.
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I finally put together a website for all the Russian/Soviet pharma research I’ve been digging through. molekul.io Figured this would be a lot easier than trying to search through months of my posts every time you want to find something. Peptides, actoprotectors, nootropics, papers, old Soviet research, obscure compounds, etc. It’s still very much a work in progress. I’ll keep adding papers, compounds and research as I find it. Basically turning the rabbit hole into a searchable database. Let me know what you want me to add.
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Les « gestes barrière » devraient être toujours les bienvenus. Surtout en lieux de soins…
🔴 Le Covid qui fait son retour dans les foyers français. SOS Médecins a enregistré une hausse de 76% des consultations en une semaine. Une augmentation observée également aux urgences. Les gestes barrières sont donc à nouveau les bienvenus. #JT13H
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-endothélium/cytokines : Inhibiteurs de l'IL-6 (Tocilizumab), de l'IL-1 (Anakinra) et du TNF-α (Infliximab). -thromboinflammation/complément : Inhibiteurs de C5 ou d'autres de la voie alternative/lectine. -dysimmunité : Inhibiteurs JAK et thérapies de type Rituximab ?
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Vagus Nerve / Mast Cells / Insomnia Vagus nerve stimulation may address mast cell insomnia at its autonomic root. The vagus nerve physically innervates mast cells in the gut and directly regulates their degranulation. When vagal tone is low, this regulatory input fails and mast cells release histamine and other mediators unchecked. thelongevityvault.com/vns-ma…
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"When vagal tone drops — as in dysautonomia, postural orthostatic tachycardia syndrome, or chronic stress — the parasympathetic regulatory input to mast cells weakens. Mast cells in both the gut and brain then degranulate more readily, releasing histamine, prostaglandins, and cytokines without adequate regulatory control. Animal studies confirm this: mice under chronic stress show elevated mast cell counts in both brain and adipose tissue alongside fragmented sleep." thelongevityvault.com/vns-ma…
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