Montagne lab @EdinburghUni. We 🇲🇽🇸🇰🇺🇸🇬🇧🇭🇺🇨🇿🇨🇴🇮🇪🇪🇸🇪🇨🇦🇺🇫🇷🇲🇴🇳🇴🇳🇬🏴󠁧󠁢󠁳󠁣󠁴󠁿🇲🇦🇦🇷🇺🇦 study the blood vessels 🩸 in the brain 🧠

Edinburgh
Joined April 2021
🧠 An exciting fully funded 4-year PhD @EdinburghUni & @OfficialUoM with Drs. Ingo Schiessl, Audrey Chagnot, and myself! 📅 Deadline: Jan 9! 📝 Details are below 👇🏻 Please circulate this widely, thanks!
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Montagne Lab retweeted
Thrilled to share our new study showing how CSF crosses through arachnoid fenestrations to olfactory meningeal lymphatics: Cell cell.com/cell/fulltext/S0092… A major step toward understanding CSF exit from subarachnoid space.
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Montagne Lab retweeted
Disease causing mutations in each of these 11 genes are implicated in at least three different chronic diseases or lifespan in humans. #Aging #Longevity #Genetics nature.com/articles/s41576-0…
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Congrats @DStefancova 🥳
🚨 New preprint on bioRxiv! Pericyte loss triggers hypoperfusion, BBB dysfunction, endothelial VCAM-1/type I IFN activation, venular-like transitions & delayed white matter injury linked to human cSVD signatures. Congrats team! biorxiv.org/content/10.64898…
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🚨 New preprint 11,000+ human brain microvessels in cSVD • Early bimodal pericyte loss • Later endothelial activation w/ a venous-like inflammatory shift • ↑ capillary density with disease 💡 Suggests sequential vascular pathology, not parallel 🔗 shorturl.at/KZapP
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🚨 PhD Programme – Vascular Dementia Research New 4-year PhD funded by BHF & UK DRI. Training across UCL, Oxford, Leicester & Edinburgh with lab rotations. 📅 Deadline: 14 April 🎓 Start: Sept 2026 Apply: CV + statement + 2 refs > [email protected] Please share!
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Montagne Lab retweeted
The “exerkine” GPLD1 confers cognitive benefit by removing an alkaline phosphatase from blood vessel walls, keeping brain vasculature youthful. #alzheimersdisease @UCSF ow.ly/wAS050Yngak
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📢 PhD fellowship opportunity in Edinburg 🏴󠁧󠁢󠁳󠁣󠁴󠁿 Deadline: Friday 9 📅 Apply now 👇🏻
🧠 An exciting fully funded 4-year PhD @EdinburghUni & @OfficialUoM with Drs. Ingo Schiessl, Audrey Chagnot, and myself! 📅 Deadline: Jan 9! 📝 Details are below 👇🏻 Please circulate this widely, thanks!
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🚀 PhD opening in our lab! Join a collaborative team across the @alzheimerssoc VIDA DTC to study vascular mechanisms in Alzheimer’s disease, with access to cutting-edge imaging and molecular tools. 👉 shorturl.at/uRvW8
🚀 Fully funded 4-yr PhD @EdinburghUni & @OfficialUoM on the vascular origins of Alzheimer’s disease (advanced imaging + proteomics) Supervisors are Drs. Axel Montagne, Ingo Schiessl, and Audrey Chagnot Join the VIDA DTC & @alzheimerssoc partnership 👉 shorturl.at/uRvW8
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Montagne Lab retweeted
Scientists identified 49 proteins genetically linked to cerebral small vessel disease. This common co-pathology with #alzheimersdisease contributes to risk for ARIA. @wustl @UTokyo_News ow.ly/OrKw50XxE0n
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Excited to share our @CurrentBiology Primer written with @AudreyChagnot in the Brain-Body Interactions special issue! We discuss how the BBB works, what happens when it breaks down, and why this matters for brain and body health. @UKDRI @TheBHF shorturl.at/NNc57
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🎉 This week, we’re proud to officially launch the BHF-UK DRI Centre for Vascular Dementia Research, in partnership with @TheBHF. The centre will explore how changes in vascular health contribute to dementia - paving the way for new treatments👉 buff.ly/5ZEjQx8
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🌟 New job opportunity 🌟 Based within the UK DRI at Edinburgh, the Rajani Lab investigates the mechanisms of white matter damage in vascular and other dementias. Find out more and apply via the link 🗓️ Apply by 22 October 2025 📌 Full details 👉 tinyurl.com/22y73642
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✨ Preorders are OPEN ✨ My amazing wife just finished her very first children’s book, and I couldn’t be prouder 💛 📚 Preorder until Sept 7 📦 Shipped w/ tracking 🔗 etsy.com/shop/ElodieWho She’s poured her heart into this — every preorder, share, & boost means the world 🙌
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The first patient in Phase 1b trial for Alzheimer's disease has been dosed with the fibrin-targeting immunotherapy. I am deeply grateful to the patients, clinical centers, the team at Therini Bio, and all the scientists in my lab making the foundational discoveries on fibrin in neurological diseases and the first-in-class fibrin-targeting antibody. globenewswire.com/fr/news-re…
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🚨 Review Alert *Walking on the tightrope: the shared roles of the bridging pericytes in the brain* Congratulations Audrey Chagnot!! 🥳 Bias aside, this feels like a really meaningful piece for the cerebrovascular field! 😊 frontiersin.org/journals/cel…
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