Join Yassine Oulad El Majdoub at #CHROMtalks2026 to explore how LC×LC and SLIM ion mobility can reveal more in complex samples. Oct. 28 | 9:30 a.m. EDT Register:globalmeet.webcasts.com/star…

Cleaner spectra. More confident peptide identification. A study in Proteomics found that SLIM-HRIM reduced chimeric precursor group size by 13× when combined with quadrupole isolation, improving precursor specificity. Read more: doi.org/10.1002/pmic.70084

Daniel DeBord’s HUPO poster asks how to fully realize HRIM. SLIM enables 60–200 mobility channels at >500 Hz; DIA-PAMAF shows >10× precursor specificity. Proposed design: ~72% ion use, >60k resolution. Join the BILLIEvers VIP Club to view the poster: go.mobilionsystems.com/BILLI…

Different isomers can hide in a single signal. Inspired by the 2026 Chemistry Nobel, we’re highlighting why molecular separation matters, from biomarkers to PFAS, and how HRIM helps reveal those differences. nobelprize.org/prizes/chemis… #IonMobility #MassSpectrometry

Teatime at MOBILion! 🫖 Dan Hackman, with help from Zongyuan Chen, treated the team to a tour of tea traditions around the world, followed by a tasting and biscuits! Thanks for a fun afternoon of learning and catching up over a cup. #TeamMOBILion #TeaTime

PFOS isn’t just one structure. Erin Baker’s team resolved 7+ PFOS isomeric contributors using SLIM-based HRIM and quantified PFAS with Skyline, opening new questions about transport and accumulation. Read: pubs.acs.org/jamsef/article-… #PFAS #IonMobility

Join Lauren Royer Dissinger at Skyline Online on Oct. 14, 5:30–6:30 PM EDT, for fast, flexible SLIM data analysis using CCS. Explore a related LCGC article including Skyline’s role in PFAS screening: chromatographyonline.com/vie… #IonMobility #Skyline

🎉 Congratulations to Michael Boylan Jr., our September MOBILion Champion! Michael’s technical leadership, teamwork, and commitment to supporting colleagues raise the bar at MOBILion. Thank you for all you do, Michael! 👏

More ions. More analytes. More information. But only if you can separate them. A JASMS study paired dual ESI/plasma ionization with SLIM HRIM to reveal previously unresolved features in a complex sample, adding analytical depth. Read more: pubs.acs.org/jamsef/article-…

What’s the next bottleneck in mass spectrometry? As AI raises expectations for data quality, SLIM offers new ways to separate and manipulate ions before they reach the mass analyzer. Melissa Sherman and Frederick Strathmann share their perspective: technologynetworks.com/analy…

100K 🏃‍♂️ That’s not a typo! Congratulations to MOBILion’s David Mastrippolito on completing the Boulder Field 100K at Hickory Run State Park. Dave tackled two 50K trail loops and finished 10th overall and 5th in his age group. Way to go, Dave! 👏

Finding PFAS isn’t enough, you need evidence to trust the result. FluoroMatch IM combines ion mobility, CCS and accurate mass to prioritize likely PFAS in complex data, with a 5% false-positive rate, even without MS/MS or retention time data. Read more: pubs.acs.org/esthag/article/…

Has mass spectrometry reached a software tipping point? MOBILion’s Melissa Sherman and Frederick Strathmann discuss why better software, AI and higher-quality data will shape what comes next. Read more: technologynetworks.com/analy…

Two new approaches. One goal: deeper, faster proteome profiling. At #HUPO2026, CTO Daniel DeBord presents two posters on high-resolution ion mobility for proteomics: 🔬 PS03.174 | 2–3 PM 🔬 PS03.175 | 1:15–2:15 PM 📅 Sept. 30 | Poster Session 3 #Proteomics #IonMobility

SLIM can do more than create long separation paths. A parallel-path SLIM–QQQ architecture achieved up to 100% duty cycle and improved detection limits 1.5–3×—helping lay the foundation for PAMAT. sciencedirect.com/science/ar…

What if you could increase acquisition speed without sacrificing high-resolution separation? SLIM’s High Duty Cycle design interleaves ions across two ~12 m paths, increasing MS1/MS2 acquisition from 1.25 to 2.15 Hz. At 200 samples/day, that delivered 66% more points per LC peak.

What can PFAS isomers reveal about environmental contamination? At #AWMA2026, Sarah Choyke of Eurofins will share how HRIM distinguishes branched and linear PFAS isomers to strengthen identification and quantitation. 📅 Sept. 22 | 4:45–6:15 p.m. 📍 Durham, NC

Different labs. Operators. Instruments. Remarkably consistent CCS. Across 4 labs and 250 lipid features, SLIM-based HRIM produced an average interlaboratory RSD of ~0.1%, reproducible structural measurements that strengthen identification confidence. pubs.acs.org/jamsef/article-…

Where are the greatest opportunities for innovation in mass spectrometry? MOBILion executives Melissa Sherman and Frederick Strathmann share how simpler workflows, better separations and higher-quality data can expand what scientists can discover. technologynetworks.com/tn/ar…

Hear John McLean, PhD, at #ISC2026 in Prague! Keynote: Rapid High-Dimensional Phenomics Using LC–Ion Mobility–MS 📅Sept. 8, 8:30 a.m. Tutorial: A Practical Guide to LC-IM-MS 📅 Sept. 9, 4:30 p.m.