Urology Specialist Registrar in London, UK | Uro-Oncology & Academics | Tennis NUT 🎾 | Former @BJUIjournal Section Editor @BURSTurology VC |
London, England
Joined January 2012
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Meg Kulkarni 💙 retweeted
Great point-counterpoint at the podium today: @veerukasi arguing biparametric MRI should be the new standard of care for prostate cancer diagnosis vs @RaisBahrami making the case to keep contrast. PRIME (JAMA 2025) says bpMRI is noninferior to mpMRI for csPCa (29.0% vs 29.6%, 555 men, 22 centers). Shorter scan, no gadolinium. The counterargument: DCE still helps with equivocal PI-RADS 3 lesions and better defines lesion size, which matters for focal therapy planning. Where do you land? @FocalSociety @Endo_Society #ProstateCancer #bpMRI #PRIMEtrial #FTS2026 @JAMA_current
Meg Kulkarni 💙 retweeted
When radical nephroureterectomy means dialysis, can we safely preserve the only kidney?
Our latest multicentre study in 62 patients with UTUC and a solitary kidney evaluated long term outcomes after endoscopic kidney sparing surgery.
-Median follow up: 65 months
-73% never required dialysis
-Only 26% ultimately underwent RNU
-5 year cancer specific mortality: 20%
-Mean eGFR decline: 2.9 mL/min/1.73 m²/year
Recurrence was frequent, 70% at 5 years, highlighting that eKSS is not a one time treatment, but a long term disease management strategy requiring rigorous endoscopic surveillance.
👉 In carefully selected patients with an imperative indication, preserving the kidney can preserve much more than renal function.
Published in @BJUIjournal
Link: bjui-journals.onlinelibrary.…
#UTUC #Endourology #Ureteroscopy #KidneySparingSurgery #Urology
The study included 62 patients treated at two tertiary centres and found frequent recurrence but durable renal preservation with structured surveillance.
Meg Kulkarni 💙 retweeted
Excellent talk by Kaylee Holleman on Prmary Cilliary Dyskinesia and how our fantastic embryologists can assess sperm & ICSI outcomes @EAAndrology conference in Italy. Good to see not just endourology using “Lasers” … who knew they could be used to check sperm health
Meg Kulkarni 💙 retweeted
Another GP practice who instead of employing actual GP are instead employing non medical substitutes- here no mention anywhere of supervision - it’s like @lengreview never happened and the @NHS is simply carrying on - @rcgp very least you can write to these practices and ask why?
🚨New advert for a PA to work as a GP substitute @rcgp
‘ The PA will INDEPENDENTLY assess , diagnose and manage Pts with acute and chronic conditions‘
‘ provide first point of contact care for patients presenting with undifferentiated undiagnosed problems ‘
Meg Kulkarni 💙 retweeted
Brand new #URUK_Catalyst, 2nd day of this year's #URUK meeting @wshed Bristol
🗓13th Nov
Are you a Uro⭐️, Onco🦀, Patho🔬, Radio-logist🩻 or Scientist🧬 #EarlyCareerResearcher keen to develop a portfolio in #GU_cancer?
This is for you! lnkd.in/p/eMwzqyee
Pls circulate ♻️
Meg Kulkarni 💙 retweeted
It seems no matter the Leng review - numerous royal colleges withdrawing support and the regular issues in coroner cases - some GP are determined to keep pushing the PA agenda - forward thinking- another name for keep the power/money and don’t hire more doctors as competition
Another advert from the Elms Medical Practice in Watford
This will be the 6th PA , they’ll be ‘supervised’ by 3 GPs to assess and manage undifferentiated patients
jobs.nhs.uk/candidate/jobadv…
Meg Kulkarni 💙 retweeted
I’m not 100% sure what “200k person hours” of treatment in half a year equates to, but the sheer volume of @FudanUniversity and 🇨🇳 centres is always astonishing! 🇨🇳 is keen to collaborate; @ASTRO_org and @ESTRO_RT is firmly on the radar. #radonc @svporceddu @PeterMacCC @SimonLo21054188
Meg Kulkarni 💙 retweeted
Urinary diversion for severe pelvic radiation injury significantly enhances bowel-related quality of life. Urologists should consider this intervention for patients with debilitating post-radiation complications. tinyurl.com/26to34nz
Meg Kulkarni 💙 retweeted
We will never forget the people who lost their lives and everyone affected 25 years ago today on the 11th September 2001. We Love You New York. Our hearts are with you and we are thinking of you today. Love London
#September11 #NeverForget #NewYork
Meg Kulkarni 💙 retweeted
😋I had the privilege of writing the editorial with @sueyom for this important study led by @UCD_radonc …. Hope to share it soon! @TheLancet #radonc #lungcancer
SWOG/NRG S1914: In patients with high-risk T1–T3N0M0 early-stage NSCLC who were medically inoperable or declined surgery, adding peri-SBRT atezolizumab did not improve PFS or OS and increased toxicity.
The trial was stopped early for futility.
thelancet.com/journals/lance…
Meg Kulkarni 💙 retweeted
Pain is a late signal.
By the time a surgeon feels pain or discomfort, the exposure contributing to it may have been happening for a long time. That’s why measuring ergonomic risk matters.
#SurgicalEducation #MedicalEducation #SurgeonHealth #OccupationalHealth
Meg Kulkarni 💙 retweeted
🚨 Article Spotlight | #CurrentUrology
Could updated anatomical illustrations improve continence-sparing radical prostatectomy?
This Correspondence proposes refinements to the classic midline sagittal schematic of the prostate, bladder neck, urethra, and sphincteric complex.
🧩 Key updates:
• Clear depiction of the submucosal longitudinal smooth muscle layer
• More detailed three-layer detrusor architecture at the bladder neck
• Anatomical continuity of the detrusor apron and vesicoprostatic muscle
• A clearer surgical anatomy basis for continence-sparing techniques
🔗 doi.org/10.1097/CU9.00000000…
#Urology #UroSoMe #MedTwitter #ProstateCancer #RadicalProstatectomy #SurgicalAnatomy #Prostatectomy
Doctors have suffered the biggest salary reductions of any profession in the last 20 years, when inflation is considered.
This new research will come as no surprise to our members, but will the Government finally take notice? metro.co.uk/2026/09/09/brita…
Meg Kulkarni 💙 retweeted
Does treatment intensification really put men with prostate cancer at greater fracture risk? 🦴
sciencedirect.com/science/ar…
Impact of Treatment Intensification with Abiraterone on Fracture-related Hospitalisation in Newly Diagnosed Prostate Cancer: A Secondary Analysis of Two Randomised Phase 3 Trials Within the STAMPEDE Trial Platform
A secondary STAMPEDE analysis evaluated fracture-related hospitalisation (FRH) among 3,102 men with #ProstateCancer receiving standard therapy with or without abiraterone💊based intensification.
➡️ In metastatic disease, abiraterone significantly reduced 5-year FRH compared with standard care, both alone and with enzalutamide.
➡️No significant difference emerged in non-metastatic disease.
✅These findings challenge concerns that abiraterone-based intensification increases fracture risk, suggesting improved metastatic bone control may instead reduce clinically significant fractures.
@GrayStruan , @JanetBrown980 , @mccloskey_e , @wmcross , @MaxParmarMRCUCL , @mattsydes , @Prof_Nick_James
@OncoAlert 🚨 #LPCCC27
@Silke_Gillessen
@AOmlin
@ProfKHerrmann
@weoncologists
Meg Kulkarni 💙 retweeted
🥇 Golden Nugget
Long before laboratories, scans & blood tests, physicians used urine to help understand disease.
Turns out urine has been helping us understand our health for more than 5,000 years.
It's not waste. It's wisdom.
#WorthItsWeightInGold #UrologyAwarenessMonth
Meg Kulkarni 💙 retweeted
Time flies, and sometimes it brings you back to the same place, but in a different role.
EUREP is more than a course. It is the flagship educational programme of the European School of Urology, bringing together final-year residents to learn, discuss, challenge ideas and grow together. 12 years ago, I attended EUREP as a resident.
This days, I had the privilege of returning as faculty in the Prostate Cancer module, and PCa itself is a perfect reminder of how much can change in 12 years. Our understanding of the disease, the way we diagnose it, the role of imaging, treatment selection, systemic therapies and shared decision-making have evolved enormously. What we teach today is different from what I was learning as a resident, and that is what makes continuous education important.
Beyond the professional journey, this moment also reminds me how much the EAU @uroweb has become part of my professional home, it has been a place to learn, grow, collaborate, build friendships and feel part of a community with a shared ambition to move urology forward.
Until the next time! 🇨🇿
#EUREP26 #Urology #prostatecancer
@UrowebESU
Meg Kulkarni 💙 retweeted
Excellent two days in Manchester learning infrapubic approach to penile prosthesis. 6 cases | 2 days, 3 cases by 2pm. A fantastic theatre team.
Thank you @IPearce82 @VaibhavModgil for the brilliant training & mentorship and @Coloplast_MD for making it possible
@TheodoraStas
Meg Kulkarni 💙 retweeted
Clearly need to check my pigeonhole more often but delighted to find that our paper on the management of surgical menopause in women post-RC has inspired the front cover of the July issue
🙏🏽 @NatRevUrol for giving visibility to this often overlooked issue
#bladdercancer
Meg Kulkarni 💙 retweeted
💬 Editorial by @JAMAplusTrials Editor in Chief Alison J. Huang, MD, MAS, Thomas G. Travison, PhD, and JAMA Senior Editor Derek C. Angus, MD, MPH:
#PragmaticTrials are intended to support real-world clinical decision-making, but the term is used inconsistently across studies. A pragmatic orientation may improve the applicability of #ClinicalTrials to routine care, yet it does not justify weaker methods or reduced rigor.
📣 This September’s JAMA+ Trials Theme of the Month examines ongoing confusion and debate in pragmatic trial research, including how eligibility, intervention delivery, outcome assessment, and analysis align with pragmatic goals. Clearer design and reporting may help clinicians and health systems judge whether trial findings are usable in practice.
🔗 ja.ma/4gO0FCx
