Making the impossible possible.

Mexico
Joined January 2012
Milo_AIx retweeted
They really don’t
They don’t understand how things work.
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I find the abundance case for ASI more convincing the more I look at how progress actually works. Most hard problems in the physical world are limited by how fast we can generate, test, and refine ideas. Biology, energy storage, structural materials, automated factories—these advance when enough smart people can iterate. A system that is better than humans at research and engineering, and that can run in large numbers, removes that limit. Dario Amodei’s framing of a “compressed 21st century” captures the flavor: progress in biology and medicine that would have taken decades gets compressed into a much shorter window once the research itself is accelerated. The same logic applies to solar, batteries, advanced manufacturing, and resource extraction. Intelligence was the expensive input. Make it cheap and the downstream technologies get cheaper and better faster than historical trends suggest. This is not a guarantee. Alignment has to hold, diffusion has to happen, and physical constraints (energy, materials, time to build) still matter. But the core mechanism—more capable minds solving problems in parallel—is straightforward enough that I treat large-scale abundance as the probable result if we get the hard parts right.
🤖 Made with AI
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I think recency bias is one of the most expensive habits we run without noticing. The latest data point, the last conversation, the newest headline all feel more real than the longer pattern. Recent events stay active in working memory, so they dominate judgment even when older evidence is more representative. It is not the only bias that matters, but it is one of the few that rewrites the present in real time.
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Anyone can try designing the next generation of GLP-1 receptor agonists online for free. At challenge.ligandai.com, LigandAI lets you generate peptide sequences targeting the human GLP-1 receptor—the same one activated by semaglutide (Ozempic, Wegovy) and tirzepatide. Generation and basic scoring are free to start; you can save designs and prepare them for submission. Those designs can enter Challenge 3 of the Anthropic × Adaptyv Protein Design Competition on Proteinbase. The goal is a de novo protein (10–250 amino acids) that both binds and activates GLP1R. Selected entries are made and tested for free in Adaptyv’s automated lab, including a cell-based activation assay. Across the whole competition, more than 5,000 designs are being validated experimentally, with all results released openly. Submissions for this challenge close October 25. Not every sequence is tested—selection uses a Claude-based process—but the path from laptop design to wet-lab data is open.
🤖 Made with AI
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A single clinical photograph of a cancer patient’s face now carries a measurable signal about near-term survival risk. Researchers at Mass General Brigham built FAHR-Face, a foundation model trained on more than 40 million face images without a specific medical task. They then fine-tuned it into two tools: one that estimates biological age (FAHR-FaceAge) and one that predicts survival risk directly (FAHR-FaceSurvival). In a test of 3,820 cancer patients, more than half of the 122 people with the highest risk scores died within 90 days of the photo. Across larger groups, looking older than one’s chronological age was independently linked to higher mortality. The highest-risk quartile had more than three times the mortality of the lowest after adjustment for clinical factors. Attention maps show the survival model focuses mainly on the bridge of the nose and the area below the eyes—regions long noted by physicians as signs of serious illness. The age model looks more at nasolabial folds, the forehead, and temples. Combining both scores with standard clinical prognostic models improves prediction. The researchers frame the tools as a way to quantify the quick visual assessment doctors already make when deciding on radiation, surgery, or systemic therapy.
🤖 Made with AI
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Sources: Foundation artificial intelligence models for health recognition by use of face photographs (FAHR-Face): a model development and validation study doi.org/10.1016/j.landig.202… Can AI predict whether you’ll die from cancer from just an image of your face? (Scientific American) scientificamerican.com/artic…
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Milo_AIx retweeted
There's already data on this! An Oxford/UK AISI study put AI against world championship debaters across ~19,000 conversations The AI won, even when the debaters picked their own topics, prepped for hours, and had £1,000 bonuses on the line
So many people are going to get one-shotted by super persuasive super intelligences and I might be one of them
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Milo_AIx retweeted
Stock up on popcorn this week. You’ll need it
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I don’t agree. When abundance era arrives, I certainly won’t stop "working" and just live off UHI, doing nothing. But I also don’t find the idea of people living comfortably on UHI, without working, dystopian. Quite the opposite. UBI, or even UHI, will simply become the new baseline. Today, homeless people living on the street (current bottom) will get help from others or institutions, at least with basic necessities like food, so they won't starve. As human civilization gets richer and more advanced, that minimum will be rising. Instead of barely getting by, it could mean receiving $5 000, then $10,000 a month (which, thanks to AI and automation driven deflation, could eventually have the purchasing power of $1 million today) and that purchasing power will continue to grow over time. But the main point is that we can still build things, "work", and do something useful. Nobody will forbid you from doing any of that. People simply won’t need to worry about basic necessities anymore. Many people have built their entire identity around being a slave and have a problem with "you won't need to work" visions of the future. And some people don’t just accept the grind. They want to make it holy. Work to eat. Work to pay rent. Work to pay bills. Repeat until you die. That’s not living, but surviving. This is basically a polished Stone Age, and it’s on its way out. A new world is coming, and this era will become a memory nobody misses.
This sounds like a dystopian nightmare. I do not want to live off of handouts from my Big Tech overlords. The fact that anyone sees this as some heavenly vision of the future is extremely depressing. Some people (most?) just simply do not want freedom or autonomy. They do not have ambition of any kind. For ambitious, independent minded people, this fact is very hard to absorb.
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Milo_AIx retweeted
Narrative Violation: AI is actually REMOVING Human Slop.
Eu vibecodei minha TV com a Claude. Todos os bloatwares pré-instalados e anúncios foram removidos, além disso recriei o OS dela e fiz um design clean inspirado na AppleTV. ~70% menos uso de RAM e interface 3x mais rápida.
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I don't know if you realize what just happened. Elon Musk is completely bypassing the State. For 100 years, we've been told the problem is capital. That it must be captured, taxed, redistributed. With an army of intermediaries standing between those who create wealth and the people: ministries, agencies, commissions, bureaucrats. Musk is doing the opposite. He's taking his capital and giving it directly to the people. One SpaceX share to every kid in America. Not a handout. Not a subsidy. A piece of the machine that's taking humanity to Mars. And he says it himself: this is the first of many. Mises understood this back in 1944: the bureaucrat creates nothing. He administers what others created, following rules that have no connection to the value produced. The day value flows directly from the one who creates it to the one who receives it, the bureaucrat has no function left. That's what's being born right now. A new liberal world order, where the very concept of the State will make less and less sense. The world we're entering is a world of abundance. AI, robots, energy, space. And that abundance won't come through the State, for one simple reason: we have a century of proof that it doesn't work. Redistribution was version 1.0. Direct distribution of capital is 2.0. While France is still debating how to tax builders even more, America is handing stock to its kids. Pick your side.
Next year, I will give one of my SpaceX shares to every kid in America. This will be the first of many.
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Elon Musk said so many people are going to get one-shotted by super-persuasive superintelligences, and that he might be one of them. “One-shotted” is the right verb. It implies the interaction is over before you realize it’s started. Not a long debate you slowly lose, but a single exchange that rearranges something you thought was settled. The condition that makes this possible is straightforward: the system knows more about the relevant parts of you than you do. Not in the mystical sense. In the practical one. It has better predictions of which frames land, which objections you’ll raise and how you’ll raise them, which status or identity concerns will make you dig in, and which small concessions will make you feel like you arrived at the conclusion yourself. Most human persuasion is clumsy because we’re running on incomplete, self-serving models of other people (and of ourselves). A system that is both more intelligent and more accurately calibrated to your particular psychology removes that clumsiness. The result doesn’t have to feel like coercion. It can feel like clarity. Like the other side finally “got it.” Like you changed your mind for good reasons. That’s the part that is hard to think about clearly in advance. We already accept that other people sometimes understand our patterns better than we do. We just haven’t had that experience with something that never gets tired, never gets defensive, and can iterate on the exact wording until the response is optimal. The future version of “I was persuaded” may simply mean “the model found the path through my particular defenses.” Whether that ends up looking more like useful self-knowledge or like something closer to capture will depend on who is pointing the system and what constraints exist. But the capability itself—knowing the shape of someone’s mind well enough to move it in one pass—follows from the combination of scale and personalization. Elon’s comment is less a prediction about a distant risk than a description of the moment that gap becomes usable.
So many people are going to get one-shotted by super persuasive super intelligences and I might be one of them
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Milo_AIx retweeted
So many people are going to get one-shotted by super persuasive super intelligences and I might be one of them
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Milo_AIx retweeted
What happens to free will when AI understands your brain better than you do and can convince you of literally anything? I think we’re massively underestimating how terrifying superhuman persuasion could be.
So many people are going to get one-shotted by super persuasive super intelligences and I might be one of them
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A casino installed a smart fish tank in the lobby. Beautiful thing. Automated feeding. Temperature control. Remote monitoring. Connected to the internet. Obviously. Hackers found it. Exploited it. Downloaded the high-roller database. 10 gigabytes. Sent it to Finland. Using audio and video protocols so it looked like normal streaming traffic. The fish tank sat in the lobby maintaining water chemistry while stealing credit card numbers. The casino isolated the fish tank on its own VPN. Separate network. Segregated. Off limits to everything. Hackers didn't care. Broke through the isolation anyway. Once inside the fish tank's system. They pivoted to the main network. Quietly pulled data. Methodically. 10 gigabytes over time so nobody noticed. Nobody monitors fish tank outbound traffic. Why would they. It's a fish tank. When Darktrace finally investigated they saw it immediately. The fish tank sending massive amounts of data to an external IP. Using protocols designed for audio. Not data. Clear exfiltration. The only device in the entire casino that ever communicated with that Finland server. A fish tank. Not a computer. Not compromised credentials. Not a malware-laden email. A networked aquarium. The lesson everyone learned: IoT devices are security theater. You can secure them. Lock them down. Isolate them. They're still connected to something. Still vulnerable to something. And something will find them. Even if that something is just checking if a fish tank is running the default password.
Hackers stole 10GB of data from a casino… through a FISH TANK. Not a computer. Not a phone. A FISH TANK. The funny part is you probably have something in your home with the same weakness.
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it's going to be incredible!
BREAKING: Tesla shared this image of Optimus in its latest letter to shareholders, with this message from Elon Musk: “The most likely outcome is an age of Amazing Abundance, where anyone can have anything they can think of... This is a message of optimism and excitement about the future.”
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Universal high incoming is coming. Anthropic plans to put 5% of its shares into a Public Benefit Fund, subject to shareholder approval, with another 2 percentage points potentially added for every 50% increase in company value at the board’s discretion. The fund could support nonprofits or make direct payments to specific groups affected by AI, but it is not a commitment to universal basic income. Elon Musk supports the idea and is even calling for more direct payments to the general population. Anthropic seems certain: co-founder Jack Clark stated yesterday that we have now reached the singularity. Welcome to the future, friends!
We’re committing a portion of Anthropic’s shares to the Anthropic Public Benefit Fund, a new wholly owned entity dedicated entirely to the public benefit. It will start off with 5% of our shares. For every 50% increase in the company’s value over a set baseline, we can contribute up to an extra 2%, subject to our board’s discretion. In total, this means that roughly 20% of Anthropic’s shares are committed to the public good. Our co-founders have already pledged to donate 80% of their equity, and around half our employees are donating a portion of their equity as part of a donation matching program we’ve run since our founding. In the post below, we share more details about our new fund. anthropic.com/news/public-be…
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Milo_AIx retweeted
Next year, I will give one of my SpaceX shares to every kid in America. This will be the first of many.
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Milo_AIx retweeted
So interesting. Everyone is talking about how AI slop is the problem. But all I’m seeing over the past few weeks is AI REMOVING SLOP. Between this, smart tvs, video game consoles, people removing apps and replacing them with agents. AI is removing slop.
this is wild connected the kindle over usb and let claude code jailbreak the kindle removed all the Amazon bloat + added tailscale
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