@MikulaLab

Research group @tu_wien focusing on bioorthogonal chemistry, (bio)molecular tools, drug targeting and theranostics 🧪💨🛠💊🧬🔬

 Vienna, Austria
mikulalab.com
Joined July 2017
  • Tweets172
  • Following191
  • Followers504
21Media
Transforming Aryl-Tetrazines into Bioorthogonal Scissors for Systematic Cleavage of trans-Cyclooctenes (Hannes Mikula and co-workers) @MikulaLab @tu_wien #openaccess onlinelibrary.wiley.com/doi/…

Transforming Aryl‐Tetrazines into Bioorthogonal Scissors for Systematic Cleavage of trans‐Cyclooc...

Highly reactive aryl-tetrazines are widely used for fast bioorthogonal ligation. However, their application in click-to-release chemistry has been impeded by significantly limited release efficienc...

onlinelibrary.wiley.com
8
3
21
4,865
Incredibly delighted and grateful that our paper in Monatshefte für Chemie - Chemical Monthly has been selected for the Best Paper Award 2024 by Springer! 🤩🧪🥳 Thanks @AT_ChemSociety @springer and @Click_Chemist @MikulaLab 💪🏼 Check out the paper: lnkd.in/dzW5UM-p
1
2
13
390
Post-doc position in beautiful Vienna! 👩‍🔬 👨‍🔬 Are you a motivated PhD graduate with experience in peptide chemistry, structural biology, or biochemistry? 👨‍🎓 👩‍🎓 Find out more about our research projects, team, and opportunities at TU Wien! tinyurl.com/mpjwszkj @chemistry_tuw
5
59
3
174
20,072
In the fourth month of the year, we have our fourth ACIE publication out - check out those colourful fluorophores! onlinelibrary.wiley.com/doi/…

PyrAtes: Modular Organic Salts with Large Stokes Shifts for Fluo‐rescence Microscopy

We report here the discovery of a powerful novel fluorophore class with an imidazo[1,2-a]pyridinium core, termed PyrAtes. The synthesis was achieved in a single step, demonstrating a wide array of...

onlinelibrary.wiley.com
Universität Wien@univienna5 Apr 2024
Neue Moleküle fluoreszieren in allen Regenbogenfarben! 🌈 Ein Team um @MaulideLab, @theo_chem & Harald Sitte von der @MedUni_Wien, hat eine Reihe neuartiger fluoreszierender Moleküle entwickelt. Warum diese in der Medizin & Pharmazie unverzichtbar sind ⤵ medienportal.univie.ac.at/me…
2
32
5,481
Super excited to see that our paper on 2-pyridyl tetrazine reactivity reached 10000 views in under 2 years!🔥 Amazing to see the impact of this work. #ResearchMilestone @MikulaLab @pg12_wilko pubs.acs.org/doi/10.1021/jac…

Uncovering the Key Role of Distortion in Bioorthogonal Tetrazine Tools That Defy the Reactivity/S...

Abstract. The tetrazine/trans-cyclooctene ligation stands out from the bioorthogonal toolbox due to its exceptional reaction kinetics, enabling multiple mo

pubs.acs.org
1
6
45
2,541
I am honored and grateful to receive the diploma thesis award "GÖCH Förderungspreis" of the Austrian Chemical Society. Many thanks to my supervisor @MikulaLab as well as @AT_ChemSociety! I am ready and excited for the journey ahead! #research #PhD #bioorthogonal rules 😎🥳
2
3
14
1,020
Our latest research on radiolabeled tetrazines is now OA in Monatshefte für Chemie, part of a special issue honoring Fritz Sauter, my academic grandfather. @pg12_wilko @MikulaLab @SpringerNature link.springer.com/article/10…
1
3
1
19
2,860
MikulaLab retweeted
MikulaLab@MikulaLab2 Sep 2023
Re puzzle: The final piece of 1 of the 8 problems was created by @FinkChemistry (THX!). If you want to take on this challenge, here it is :) All you need to know: the result is a number as part of coordinates. A "scientific mindset" helps😉Don't spoil! Results only! #chemtwitter
1
2
2
711
Amazing three days together with @MikulaLab, @BrigitteHolzer1 and @birgitm16 enjoying the sun and especially the fascinating talks at @ELRIG_UK therapeutic OLIGOS & ECBS2023 @EuChemS at the beautiful Site of @AstraZeneca Gothenburg. Thanks for having us!
3
16
869
#OnTheCover Substituent Effects in Bioorthogonal Diels-Alder Reactions of 1,2,4,5-Tetrazines (Dennis Svatunek and co-workers) onlinelibrary.wiley.com/doi/… @Click_Chemist @MikulaLab @tuvienna
3
13
2,394
Excited that our work on tetrazine reactivity is featured as a cover picture. Great artwork by first author Nici highlighting the importance of asynchronicity. Read the open access article here: chemistry-europe.onlinelibra… @MikulaLab #clickchemistry #compchem @ChemEurJ
1
1
29
2,023
📢📢Last day to apply for our PhD position & Postdoc position📢📢 please RT. Thanks! olallalab.org/join-the-team/ – at Pontevedra, Spain

Join the Team - OlallaLab

“Everything we want is outside of our comfort zone”  Our multicultural lab are fully committed to foster equity, diversity and inclusion in science. We have a strong team spirit, which is expected...

olallalab.org
6
80
116
29,834
Out in @J_A_C_S! Ligand-directed catalysts for live-cell, photocatalytic activation of dihydrotetrazines coupled to new uncaging chemistry. Congratulations to Jules @RosenbergerJE, Yixin, Fang, Xinyi, Will and Olga! Thanks for support from NIGMS and @Pfizer #PfizerChemistry
5
13
4
93
29,564
Our contribution to the special issue in honor of Ken @houk1000 Houk's birthday in @ChemEurJ is now online: "Substituent Effects in Bioorthogonal Diels–Alder Reactions of 1,2,4,5-Tetrazines". @MikulaLab #clickchemistry #bioorthogonal #compchem 1/3 doi.org/10.1002/chem.2023003…

Substituent Effects in Bioorthogonal Diels–Alder Reactions of 1,2,4,5‐Tetrazines

Non-frontier molecular orbital interaction-controlled reactivity: The reactivity of 1,2,4,5-tetrazines in inverse electron demand Diels–Alder cycloadditions is often described by using frontier...

chemistry-europe.onlinelibrary.wiley.com
2
5
28
2,593
New PhD position open! The project is on devices for electrically controlled chemotherapy to treat hard-to-treat cancers in vivo. don't hesitate to contact me for more information! phd-recruiting.medunigraz.at…
1
3
7
992
We are growing🚀🚀🤩🤩 We are looking for🔎🧐 1) PhD students with a strong background on organic chemistry of dyes 2) a chembio lab technician with experience in synthesis & bio techniques. Please 🙏 retweet & pass it forward! 🧑‍🔬👩🏾‍🔬Interested?🤩Reach me by email📩 Thanks!
5
134
1
174
39,113
#OnTheCover Tetrazine-Triggered Bioorthogonal Cleavage of trans-Cyclooctene-Caged Phenols Using a Minimal Self-Immolative Linker Strategy (Mikula) @MikulaLab @tu_wien @JCTCarlson @Patrick_Keppel onlinelibrary.wiley.com/doi/…
1
10
Preparations for our interactive exhibit on in vivo chemistry at the #EuropeanResearchersNight this Friday are ongoing. It's gonna be a #fluorescenceFriday! You can find us at the Vienna location. @MikulaLab @exploREsearchAT #exploREsearch researchersnight.eu/in-vivo-…
2
15
I am very pleased to be selected under the top 10 of the posters of ARIT 2022 about work done in @MikulaLab and @WeisslederLab with @JCTCarlson🙏🏼 Since only the top 3 are getting awarded, 🏆 please vote for my poster&talk! 🙌🏼 Bioorthogonal Turn-Off m.shortstack.page/G4QN06?sre…
1
6
Hot off the press - imaging will never be the same again!
5
129
7
868
Load more