MBT has received a score of 9.9 in the latest Cite Score rankings! We are thrilled to be in the top 12% of Applied Microbiology and Biotechnology journals. THANKS to our incredible readers, contributors, staff members, and editors for their unwavering support!!!

Synthetic biology rewires carbon metabolism in Bacillus methanolicus by installing a heterologous phosphoketolase pathway, boosting methanol-to-biomass yields by up to 24% while cutting CO₂ loss. A step forward for sustainable C1 biomanufacturing. doi.org/10.1111/1751-7915.70…

Victor de Lorenzo, a field leader, revisits the environmental release of genetically engineered microorganisms, arguing for a shift from containment-focused regulation to stewardship, traceability, and responsible ecosystem restoration. Read details at doi.org/10.1111/1751-7915.70…

A lovely moment at La Granja! 4 of our Associate Editors(Auxi, Pablo, Harald, Juan L.)came together during the Biannual Meeting of the European Academy of Microbiology, sponsored byFEMS. Great to see our editorial community connecting, sharing ideas & strengthening collaborations

As zoonotic threats continue to emerge, a rapid one-pot RPA-CRISPR/Cas12a assay enables ultra-specific detection of Monkeypox virus Clade I in just 40 min, supporting faster field surveillance and outbreak response. New from Li et al at doi.org/10.1111/1751-7915.70…

New from Perez-Muelas et al.! Stenotrophomonas bentonitica BII-R7 combines exceptional multimetal resistance with biofilm-guided synthesis of crystalline selenium nanorods, opening new avenues for bioremediation and green nanotechnology. Read doi.org/10.1111/1751-7915.70…

New from Ball et al.! Bacteriophages slashed Pseudomonas syringae on highbush blueberry leaves by >100,000-fold, highlighting phage cocktails as a powerful, sustainable plant disease control strategy. Don’t miss Microb Biotech: doi.org/10.1111/1751-7915.70…

VACCINES: Vicente-Pazos et al. advance DNA vaccine development against Klebsiella pneumoniae, showing that plasmid backbone design can strongly influence immune responses & protection against sepsis. The pVAX1-MrkA vaccine achieved 80% protection in mice. doi.org/10.1111/1751-7915.70…

Protein engineering: Pranoto et al. show that the hydrophobic core of a Bacillus subtilis α-amylase signal peptide can be shortened by ~60% without compromising secretion efficiency. A step forward in the rational design of protein production systems. doi.org/10.1111/1751-7915.70…

Xu et al. report that washed microbiota transplantation(WMT) showed promising feasibility & safety as salvage therapy for refractory non-CDI gut infections in critically ill patients, with 50% achieving clinical cure & no serious WMT-related adverse events.doi.org/10.1111/1751-7915.70…

Can eye microbes help combat myopia? Yanqing Li et al. show that Lactobacillus mucosae MM-1 and its metabolite indole-3-lactic acid reduced lens-induced myopia in mice via AHR activation and TGF-β/Smad inhibition. Advancing science! doi.org/10.1111/1751-7915.70…

Barcelos et al. explore how biomanufacturing can scale from lab to industry, converting waste carbon into biofuels, biochemicals, and biomaterials. Integrating biology, process engineering, modelling, and economics is key to a sustainable bioeconomy. doi.org/10.1111/1751-7915.70…

Li et al. uncover how indigenous fungi from mine tailings oxidize pyrite through distinct mechanisms, from organic acid secretion to peroxidase-driven pathways. A step forward for bioleaching and mining biotechnology. doi.org/10.1111/1751-7915.70…

GUT MICROBIOME: Zhang et al. report that Bifidobacterium animalis subsp. lactis CP-9 safely enriched beneficial Bifidobacterium in healthy infants and improved gut tolerability over 3 months. Find more on Probiotics at doi.org/10.1111/1751-7915.70…

CIRCULAR ECONOMY: Laura de Eugenio et al discuss that enzymes can help tackle plastic waste, but no single technology will deliver circularity alone. A systems approach to plastics & bioplastics is key. Find their OPINION at doi.org/10.1111/1751-7915.70…

ANTI-PHAGE: Bacteria deploy remarkably diverse defenses against viruses, from DNA injection blockers and nucleases to immune-like systems resembling gasdermins, Argonautes and ubiquitin pathways. Thousands of anti-phage systems remain to be discovered. doi.org/10.1111/1751-7915.70…

GREEN TECH. TolC is a key missing piece in mixed-linkage β-glucan (MLG) biosynthesis. Engineering Sinorhizobium meliloti with tolC, bgsBA and pleD boosted MLG production up to ~10 g/L and enabled synthesis in new bacterial hosts. doi.org/10.1111/1751-7915.70…

METABOLISM. In vivo catalytic rates of 99 enzymes in formate-grown Methanococcus maripaludis reveal weak agreement with sequence-predicted turnover numbers, highlighting low enzyme saturation as a key constraint in C1 metabolism and bioengineering. doi.org/10.1111/1751-7915.70…

SYNTHETIC BIOLOGY: Can we predict quorum sensing behaviour? A validated mathematical model helps fine-tune EsaI/EsaR genetic circuits, accelerating synthetic biology design. Relevant advances by De Baets et al. doi.org/10.1111/1751-7915.70…

MORE THAN POLLINATORS: Honey bee gut microbes may be an overlooked detox organ. A new perspective proposes harnessing the microbiome to protect pollinators from pesticide exposure. Read the Opinion article by Liu et al. doi.org/10.1111/1751-7915.70…

GLYCOBIOLOGY. Sugar matters! Optimizing N-glycosylation doubled the production of a fungal peroxygenase in yeast, improving recombinant enzyme yields for industrial biotechnology. Very relevant research presented by Schramm et al. doi.org/10.1111/1751-7915.70…