Researching reproducibility and creating the best and most comprehensive toolkit for "AI peer review" and forensic metscience. Run by @moreisdifferent.

Boston, MA
Joined February 2021
The Metascience Observatory@MetascienceObsOct 5
"We measure AI-generated writing in the dissertations of a near-census of US STEM PhD graduates from 2019 to 2026 and link graduates to their subsequent employment. AI writing is absent before 2023, present in 29% of dissertations filed in 2026, and rapidly growing." (link below)
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The Metascience Observatory@MetascienceObsOct 4
A paper recently came out claiming to show that nuclear power plants cause cancer. Using the exact same methodology, researchers at @TheBTI showed the following also "cause cancer". (link below)
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The Metascience Observatory@MetascienceObsOct 2
.@arXiv is making some updates in light of a deluge of paper submissions: blog.arxiv.org/2026/10/01/up…
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The Metascience Observatory@MetascienceObsOct 1
Interesting. "Robustness is better assessed with a few thoughtful models than with billions of regressions" pnas.org/doi/abs/10.1073/pna…
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The Metascience Observatory@MetascienceObsSep 24
"... almost all participants had experience with irreproducibility... 58% had failed to replicate a result from the published literature.... Participants reported feelings of self-doubt, frustration, and depression while experiencing irreproducibility.. " journals.plos.org/plosone/ar…
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The Metascience Observatory@MetascienceObsSep 15
Here's the duplication issue we found in "LDL receptor-related protein-1 is a sialic-acid-independent receptor for myelin-associated glycoprotein that functions in neurite outgrowth inhibition by MAG and CNS myelin" - It's awaiting moderation here: pubpeer.com/publications/E2C…
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The Metascience Observatory@MetascienceObsSep 15
We found another duplication issue in the @J_Cell_Sci paper Sholto found issues in (10.1242/jcs.113191). Sholto suggests looking at PhD theses. In one co-author's PhD thesis we found same image but w different coloration and diff labels. Video shows transform & blink comparison.
A new video for my YouTube channel, this one is about image manipulation in a Nature Neuroscience Paper by researchers at the University of Michigan. youtube.com/watch?v=3R6VsFNd…
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The Metascience Observatory@MetascienceObsSep 11
We found a minor duplication issue in the supplementary info of 2017 Oncogene paper. What's interesting is this is from the lab of Dr. Kenneth Anderson at DFCI. @addictedtoigno1 previously flagged 16 of his papers previously as part of case that ended up causing quite a stir..
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The Metascience Observatory@MetascienceObsSep 10
We're flagging a case of cross-paper image reuse, submitted to pubpeer. The 2014 paper caption says the image shows "EGFP expression in pAcISUBC transfected BuMECs" pAcISUBC is a human insulin expression vector constructed in the 2014 paper that does not appear in 2013 paper.
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The Metascience Observatory@MetascienceObsSep 9
IMAGE DUPLICATION DETECTED Nature Medicine 18, 892–901 (2012). The cells in Fig. 1 are described as from a human patient, while the matching cells in Fig 6 are described as from a tumor grown subcutaneously in a mouse from human cells (a "mouse xenograph").
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