PhD student at Josep Carreras Leukaemia Research Institute @CarrerasIJC @Menendez_Lab Bioinformatician 💻🔬 T cells & CAR T cells 🧪🧫

Barcelona
Joined May 2014
Wrapped up my first week of my #PhD stay in @roserventotormo ’s lab at the @sangerinstitute 🙌🧬💻 Huge thanks to the @EHA_Hematology Grant Mobility fellowship for supporting this. Now just need to survive the British rain 🌧️😂
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Just attended an insanely good talk by @PolonenPetri on omics-based classification of T-ALL at #EHA2025 🧬👨🏼‍💻So inspiring… science at its best!
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Funny days at the #TERAV 2024 annual meeting. Lots of interesting science & a great opportunity for networking @red_terav
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It is always a pleasure to come back to #KindPhilipp2024 . One of a kind meeting, great science and even better scientists 🧑🏼‍🔬👩🏻‍💻
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Let’s start the second day #ISCO2024 Good weather, great location and fantastic science 🤓
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Are ɣδ T cells important? 🥰 The ɣδ T cells are expanded in the better prognosis patients (2 & 5) & are super cytotoxic. So we VALIDATED this result on a cohort of a 58 DLBCL patients.
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BUT 😱 Another cell type have a hyperextension, but we could not see it through TCR seq, because these cells are ɣδ T cells (only ɑβ are sequenced)
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🤔And... what cells contribute to the efficacy of the treatment? By scTCRseq we can see the huge expansion of CD8 cytotoxic T cells, leading the response.
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⚠️ And we have VALIDATED this results with 18 more patients! Almost all patients with 75% of CD4+ cells at IP achieve a complete response and have better survival.
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