Neuroscience. Locus Coeruleus and Noradrenaline.
Zurich, Switzerland
Joined June 2018
- Tweets117
- Following267
- Followers161
- Likes1.5K
Mattia Privitera retweeted
During moderate tonic locus coeruleus activation in mice, noradrenaline release engages cortical regions related to associative processing, while burst-like stimulation biases the brain toward sensory processing
nature.com/articles/s41593-0…
Mattia Privitera retweeted
Out now in @NatureNeuro: "Centripetal integration of past events in hippocampal astrocytes regulated by locus coeruleus", nature.com/articles/s41593-0…
With a great team: @FritjofHelmchen @BohacekLab @SianDuss @cloois and (twitterless) Denise Becker. 1/5
Mattia Privitera retweeted
🔵 Noradrenaline directly regulates gene expression in the brain. 8 years in the making, now finally published in @eLife 🥳
During revisions, we added 32 RNAseq samples and a meta-analysis of 71 RNAseqs to rule out major sex differences. #stress
Please RT
elifesciences.org/articles/8…
🚨🔵🚨
Our work on stress-induced gene expression changes mediated by #LocusCoeruleus #noradrenaline has now been reviewed by @eLife !🥳🤩
We got constructive and positive feedback 🙏, and we're tackling those pesky sex effects once more #revisions
elifesciences.org/reviewed-p…
Mattia Privitera retweeted
I am not on instagram but thanks to @SRF our PROTAC is @BohacekLab @MGazorpak @CarreiraGroup @bel_ethz @MiriamKretschm2 @SelinaJoyFrei
@iivanova0541
@MattiaPri instagram.com/reel/C2fnYdBOK…
srf.ch/play/tv/srf-news-vide…
Mattia Privitera retweeted
The first cellular map of a mammalian brain is here. 🧠✨
Over 6 years and 32 million cells in the making, the complete adult mouse brain cell-type atlas reveals astonishing diversity and regional specificity.
Dive deeper: alleninstitute.org/scientist…
@nature #studyBRAIN #BICCN
Mattia Privitera retweeted
A new review paper led by @mj_dahl, Agnieszka Kulesza and @WB_Markus. We review how deficient #dopaminergic and #noradrenergic modulation of hippocampal plasticity may contribute to memory loss in aging and Alzheimer's disease sciencedirect.com/science/ar… #locuscoeruleus
Mattia Privitera retweeted
That's all folks!
You gave me everything.
I gave you everything.
We did it together.
Mattia Privitera retweeted
🚨In our latest preprint🚨 we propose a radical change to the analysis of rodent #behavior in preclinical research.
Featuring @DeepLabCut ♥️
Check out the manuscript and the 🧵👇
xitter.cf/biorxiv_neursci/status…
Analysis of behavioral flow resolves latent phenotypes biorxiv.org/cgi/content/shor… #biorxiv_neursci
Mattia Privitera retweeted
1st preprint of the Gapplab! Check out our PROTAC tool to mingle with stress hormone receptor signalling A fun collaborative effort by @Carreiralab @BohacekLab @bel_ethz @Meijer_Lab @GermainPl
Lead by stellar students @MGazorpak & Karina Hungentobler biorxiv.org/content/10.1101/…
Mattia Privitera retweeted
🔵 In 2016 I wrote a grant, in which @MattiaPri and I asked a simple question:
Stress triggers massive transcriptional changes, which of them are dependent on noradrenaline (NA) signaling?
Today, we have the answer. But boy was this a journey. 🧵👇
biorxiv.org/content/10.1101/…
Mattia Privitera retweeted
New Nature paper provides evidence that science has become less innovative since the 1950s. The authors suggest reversing the trend by:
1. reading widely,
2. focusing less on quantity of papers, & more on research quality,
3. taking year-long sabbaticals.
nature.com/articles/s41586-0…
Mattia Privitera retweeted
For the first time, farmers in the #Philippines have cultivated #GoldenRice on a larger scale and harvested almost 70 tonnes of grains this October.This nearly never-ending story began at ETH Zurich. #betacarotene #vitaminA #HiddenHunger ethz.ch/en/news-and-events/e…
Mattia Privitera retweeted
The gene expression landscape of the human locus coeruleus revealed by single-nucleus and spatially-resolved transcriptomics biorxiv.org/cgi/content/shor… #biorxiv_neursci
Mattia Privitera retweeted
The locus coeruleus mediates behavioral flexibility biorxiv.org/cgi/content/shor… #biorxiv_neursci
Mattia Privitera retweeted
Locus Coeruleus firing patterns selectively modulate brain activity and dynamics biorxiv.org/cgi/content/shor… #biorxiv_neursci
Mattia Privitera retweeted
NEW PREPRINT FROM THE LAB📢📢: Locus Coeruleus firing patterns selectively modulate brain activity and dynamics! 3y in the making and this work is finally seeing light thanks to a fantastic teamwork! C Grimm, S Duss and @BohacekLab. Short thread ⬇️ biorxiv.org/content/10.1101/…
Mattia Privitera retweeted
Very happy to share my lab’s new paper out in @PNAS. doi.org/10.1073/pnas.2116507…
Mattia Privitera retweeted
Wild new research tool alert!🤯If you plug a research question into elicit.org, it uses AI to not only find relevant papers but pulls out ANSWERS from the papers. Adding to my list of things that would've changed the game at the start of my PhD #AcademicTwitter
ALT Screenshot of a software called Elicit. A box contains a research question "do pregnant women have reduced cognitive performance?" and underneath are answers from the literature that address this question.
Mattia Privitera retweeted
Our multiomic screen of the changes triggered by acute #stress in the hippocampus is now out in @NatureComm 🥳
Don't miss the wild preprint trailer👇and follow the 🧵 to find out what has changed during the review process. We added (and removed!) a lot! nature.com/articles/s41467-0…
🚨PREPRINT ALERT🚨 Our latest work provides a multiomic dissection of the molecular changes triggered by acute #stress. It comes with an interactive app that will make stress researchers jump with joy! Thread and a wild trailer by @Osturmscience below 🔊👇biorxiv.org/content/10.1101/…