@Massie_Lab

Using genetic and epigenetic alterations found in early stage cancers we develop novel assays to help detect aggressive cancers at an early and treatable stage

 Cambridge, England
earlydetectioncambridge.org.uk/research/groups
Joined April 2018
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  • Followers328
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📢 We're recruiting a Medical Imaging AI researcher! Exciting project @CRUKCamBCVI (jointly shared with Mair and Price labs), integrating novel imaging datasets (DMI/MRI/PET) with whole genome & transcriptome data for real time clinical decision making. jobs.cam.ac.uk/job/38516/
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Still time to register for our in person seminar by Angela Goncalves @afilimon this Thursday
Early Cancer Institute, University of Cambridge@EarlyCancerCam16 Nov 2022
We are delighted to announce the second in our new seminar series - @afilimon on Somatic evolution during ageing and carcinogenesis. 📅 Thursday 8th December, 12.30-14:00 including lunch! Clifford Allbutt Lecture theatre, CB2 0AH 👉Register here: earlycancer.cam.ac.uk/events…
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Congratulations to our Institute Director @RFitzgerald_lab !
Cancer Research Horizons
@CR_Horizons6 Dec 2022
.@CR_UK CEO, @Michelle_CRUK congratulates Rebecca Fitzgerald, the winner of our Impact Recognition Award, for her outstanding contribution to #oncology and her determination to drive forward the translation & commercialisation of her discoveries for patient benefit. #IEAwards22
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Congratulations @RFitzgerald_lab @EarlyCancerCam - a very well deserved Impact Recognition Award🏅👏 !
Cancer Research Horizons
@CR_Horizons6 Dec 2022
.@CR_UK CEO, @Michelle_CRUK congratulates Rebecca Fitzgerald, the winner of our Impact Recognition Award, for her outstanding contribution to #oncology and her determination to drive forward the translation & commercialisation of her discoveries for patient benefit. #IEAwards22
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🧵 UM researchers have used #AI to distinguish between four #RenalCancer subtypes. This tech has the potential to improve pre-surgical diagnosis and avoid unnecessary surgery. This excellent thread by @IzzyNewsham explains all 👇
Izzy Newsham@IzzyNewsham30 Sep 2022
Replying to @IzzyNewsham
Although Renal Cell Cancer (RCC) is one of the most common cancers worldwide, existing diagnostic strategies are unable to accurately differentiate malignant from benign small renal masses preoperatively. This results in 20% of patients undergoing unnecessary surgery. 2/10
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I am extremely enthusiastic to share our work published today in @NatureGenet. We establish a targeted @nanopore sequencing approach for ultralong-read epigenomic profiling and discover a novel, primate-specific enhancer driving bi-allelic IGF2 expression. nature.com/articles/s41588-0…
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📢Congratulations @srossi725, PhD student in @Massie_Lab, whose paper on improving diagnostic accuracy of renal masses using a bespoke machine-learning model was published in @ScienceMagazine yesterday. science.org/doi/10.1126/scia…

Accurate detection of benign and malignant renal tumor subtypes with MethylBoostER: An epigenetic...

The MethylBoostER machine learning model improves the diagnosis of kidney tumor subtypes by utilizing DNA methylation patterns.

science.org
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✨Congratulations✨ to UM Lead @grantissimus, who's been awarded a King James IV Professorship by @RCSEd
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This is another paper from the CRUK-ICGC Prostate group that have been workling together for over 10 years and driven by Claudia Buhigas' PhD work. @davidcwedge @dralynch @Massie_Lab @EelesRos @VincentGnanapr3 etc.
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On the day of our official launch, Institute Director Rebecca Fitzgerald @RFitzgerald_lab is interviewed on @BBCr4today. Listen to the interview at 1:21:48. #EarlyCancerCamLaunch bbc.co.uk/sounds/play/m001c6…
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"We want to focus on some of the hardest cancers to treat where early detection could really make a difference." Prof Rebecca Fitzgerald on @BBCr4today about the launch of the UK's first Early Cancer Institute @Cambridge_Uni @EarlyCancerCam @CRUKresearch bbc.co.uk/news/uk-england-ca…

UK's first Early Cancer Institute is launched in Cambridge

Scientists at the new institute will devote their expertise to detecting and studying cancers early.

bbc.co.uk
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An exciting opportunity to join our dynamic teams as part of an international collaboration on leading-edge methods for cell-free DNA methylation assays to facilitate effective cancer early detection: jobs.cam.ac.uk/job/36196/
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📢Open to all: ACED Prostate Cancer virtual symposium 25th May 17:00 BST/09:00 PDT - 19:30 BST/11:30 PDT. Join to hear about #ACEDearlydetection funded prostate cancer projects @CanaryCenter @OHSUKnight @MCRCnews @UCLCancerECN @CRUKCamUrol Sign up here eventbrite.co.uk/e/aced-pros…
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We are looking for highly motivated Research Associates to join an exciting collaborative project (UCL, Stanford, Cambridge) exploring the use of novel epigenomic methods for cancer early detection: jobs.cam.ac.uk/job/34881/ @AndyFeber and Richard Mair mair-lab.com
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We're looking for a new Research Nurse to join the UM team. Know a registered nurse with oncology or clinical trials experience, who can work in a self-directed, independent and flexible manner? Send them our way 👉jobs.cam.ac.uk/job/32001/
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Cervical cancer rates reduced by 87% HPV vaccination! To celebrate the results of our paper on HPV vaccination we spoke to Emeritus Professor of Epithelial Biology @Cambridge_Uni, Margaret Stanley about her lifetime in HPV research. bit.ly/3mCQq7Q
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We know there's positive selection for mutations in cancer-associated genes in healthy tissues. But how much positive selection is there elsewhere in the genome? @gladyspoon investigated in our paper just out in @NatureGenet nature.com/articles/s41588-0…
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In case you want to read the actual paper authors.elsevier.com/a/1e0r5…
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👏🎉Huge congratulations to @SerenaNikZainal awarded the 2021 @acmedsci Foulkes Foundation Medal for personalising treatments for cancer patients by identifying specific patterns of mutations in tumours @CRUKresearch @CUH_NHS @Cambridge_Uni ➡️ crukcambridgecentre.org.uk/n…
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Invited by @Massie_Lab and should be of interest to all @UniversityCamb
CRUK Cambridge Centre: Urological Malignancies@CRUKCamUrol27 Oct 2021
Register now to hear Dr Jeremy Clark's talk, 'The PUR (Prostate Urine Risk) biomarker for prostate cancer detection and prognosis', on 18 November 2021 at 4.30pm at the CRUK Cambridge Institute Lecture Theatre! Register here: eventbrite.co.uk/e/194594747…
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