Dr. Eduardo Marban | Executive Director, Smidt Heart Institute @CedarsSinai Views are my own, not institutional policy!
Cedars-Sinai Medical Center
Joined May 2021
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Eduardo Marban, MD, PhD retweeted
Suggesting a novel therapy for #SystemicSclerosis: doi.org/10.1172/jci.insight.…
Eduardo Marbán & team @Marbanlab @CedarsSinai report that an orally delivered noncoding RNA (TY1) reduces inflammation and organ fibrosis in models of systemic sclerosis through inhibition of the cGAS/STING axis. The authors employed in vitro and in vivo models and evaluated skin, lung, and heart.
The video shows TY1 treatment in preclinical models of systemic sclerosis.
@AleCiulloPhD @TheIbrahimlab @the_asci
Eduardo Marban, MD, PhD retweeted
Noncoding RNA TY1 reverses fibrosis in systemic sclerosis by attenuating the cGAS/STING pathway @JCI_insight @MarbanLab
insight.jci.org/articles/vie…
Eduardo Marban, MD, PhD retweeted
Percutaneous Atrial Delivery of TBX18 Creates a Stable Supraventricular Biological Pacemaker in Porcine Sick Sinus Syndrome | JACC: Clinical Electrophysiology jacc.org/doi/10.1016/j.jacep…
@JACCJournals #JACCEP #Biopacer
#Biopace #CRM #RhythmsAndMore
Eduardo Marban, MD, PhD retweeted
Behind the scenes: Ciullo and team develop an exomer drug based on a naturally occurring RNA and investigate its bioactivity in acute sepsis.
@AleCiulloPhD @TheIbrahimLab @MarbanLab @Kara_tsi @anhhnguyennn9 @Hiroaki_komuro @XMichaelJonesMD @SmidtHeart
Eduardo Marban, MD, PhD retweeted
Wanted to post this article from Cedars-Sinai (penned by Kristin Reynolds) remembering my dear friend, Kiel Allen Peck and the lasting contributions he made to translational medicine and the lucky people who knew him.
Eduardo Marban, MD, PhD retweeted
Today at the @CedarsSinai @RareDiseases day, @MarbanLab and @rrogerslab elegantly outline the drug discovery potential of mining therapeutic extracellular vesicles for novel RNAs. What would later be called the "CREDO" paradigm has been @MarbanLab's vision for nearly two decades and what a privilege to see it materialize!
Here's to emergent mechanisms, novel drugs, and renewed hope for rare disease patients.
Eduardo Marban, MD, PhD retweeted
Check out this week's seminar!
Join us January 15th as Dr. Eugenio Cingolani from Cedars-Sinai's Smidt Heart Institute presents novel approaches to treating arrhythmogenic cardiomyopathy.
See the flyer below for more info!
@RobinShawCVRTI #hearthealth #cardiovascularresearch #seminar
Eduardo Marban, MD, PhD retweeted
Truly outstanding #cardiology @SmidtHeart Grand Rounds by @SumeetSChugh - Present and Future of #AI in #Medicine and #Science ➡️ #GenAI ➡️ #DigitalTwins ➡️ #DiseasePrediction @CedarsSinaiMed @CedarsSinai #TheFutureIsNow
Eduardo Marban, MD, PhD retweeted
Los Angeles residents saw significant rises in cardiopulmonary illness in the 3 months after the Jan 2025 Eaton & Palisades wildfires, per a study in #JACC. Findings are based on Cedars-Sinai ED data compared with the same period in 2018–2024. jacc.org/doi/10.1016/j.jacc.…
Eduardo Marban, MD, PhD retweeted
Indeed! In our @stemcellreports article, we show that early and continuous intervention with #deramiocel preserves muscle function well into old age in mice with #DMD.
Link to article: cell.com/stem-cell-reports/f…
This development will enable earlier diagnosis and pre-symptomatic interventions in #DMD— a great prospect.
Eduardo Marban, MD, PhD retweeted
Special privilege to share the podium today with @gracielagon and @AjhungMD this evening at the @CedarsSinai Annual Board Meeting, to share advances in #HealthAI at our institution. Special thanks to @MarbanLab for the photos!
Eduardo Marban, MD, PhD retweeted
Join us in thanking chairperson @JoChikweMD, vice-chair @bnallamo and American Heart Association president @drstaceyrosen for bringing #AHA25 to life! We are grateful for their leadership and dedication to shaping the future of cardiovascular health.
Eduardo Marban, MD, PhD retweeted
Day 1 of 12 Days of #ProBowlVote Giveaways!
🔁 Repost to win a signed Matthew Stafford mini helmet!
Eduardo Marban, MD, PhD retweeted
We developed a drug discovery paradigm based on novel small RNAs from therapeutic extracellular vesicles. Started in 2019 and published this morning!
Next stop, the clinic! @MarbanLab @AleCiulloPhD
science.org/doi/10.1126/scit…
Eduardo Marban, MD, PhD retweeted
Development of new #MinimallyInvasive #Technique to deliver #Biopacer - Great team work by James / @T_Ikenouchi / Ralf / Juan / Ed - @SmidtHeart @CedarsSinaiMed @CedarsSinai @MarbanLab #Biopace #CRM #rhythm #pacemakers ➡️ more to come soon!
Eduardo Marban, MD, PhD retweeted
Honored to receive the AAEV Founder’s Award and to be inducted into the inaugural class of Fellow of AAEV at the 2025 @AAEV_org Annual Conference in Salt Lake City. Grateful to my team, collaborators, and the EV community for their support and commitment to advancing EV research.
