@Marand_Labi
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Assistant Professor @UMich. Chromatin biology, cis-regulatory dynamics, plant genomes.
Ann Arbor, MI
Joined May 2017
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Alexandre Marand retweeted
I am proud to share my No-AI-assisted perspective review "Plant Peptide Hormones: Three Decades of Discovery and Emerging Paradigms" for the Centennial issue of @PlantPhys🌱🍅. It's OA, so everyone can access! 1/
academic.oup.com/plphys/adva…
Alexandre Marand retweeted
Ever observe maize produce 90 leaves before flowering? See Mark's and Zuhaa's preprint for their new proposed flowering time model.
Multimodal single cell analysis reveals a link between flowering and leaf initiation biorxiv.org/content/10.64898…
Alexandre Marand retweeted
‼️A new story from our lab!🙌 We show that SNI1, a component of the SMC5/6 complex, acts as a temperature-dependent brake on class II crossovers, helping shape where genetic exchange occurs in Arabidopsis. Huge effort by Alex made it happen🙏
1/2 My very first post on X—and what better occasion than the publication of our paper in @NaturePlants! 🌱
We identify SNI1 as the first plant gene linking temperature to meiotic recombination, generating genetic diversity that may help plants adapt.
nature.com/articles/s41477-0…
Alexandre Marand retweeted
🚨How many reads in a single-cell barcode come from that cell? 🚨
We loaded maize and Arabidopsis nuclei into separate wells of the same scifi-ATAC plate.
Arabidopsis barcode averaged 73% maize reads, yet standard QC looked normal!
New preprint 🧵
biorxiv.org/content/10.64898…
1/10
🚨New preprint🚨 from super postdoc, @FabioGomezCano1, on modeling and removing ambient contamination (i.e. nuclei-free chromatin 🧬) in single-cell scifi-ATAC-seq experiments using his new tool, AmbientMapper.
biorxiv.org/content/10.64898…
Alexandre Marand retweeted
📣 Please share!
We’re recruiting to build predictive models of gene regulation in plants. We’d love to hear from anyone with strong foundations in regulatory genomics or ML and fluency with coding agents. Any career stage; no plant background needed. noborilab.org 1/4
Excited to launch our ERC project ImmuneCellState 🚀
We’ll study how individual plant cells respond to pathogens and explore new dimensions of plant immunity research by integrating single-cell/spatial omics, deep learning and genome editing.
@TheSainsburyLab @ERC_Research
Alexandre Marand retweeted
Great work by Ingram & Zipfel labs. Congratulations, everyone!
An embryo-derived peptide signal directs endosperm polarity in Arabidopsis
science.org/doi/10.1126/scie…
Alexandre Marand retweeted
My MCDB Dept is hiring, again!
Assistant Professor Faculty Search. Please Repost! Applications Due Oct 1st
We welcome applications from all areas of cellular/molecular biology in prokaryotes, plants, and animals.
More info can be found HERE: jobs.sciencecareers.org/job/…
Alexandre Marand retweeted
Our new Review is online!
Nutrients can act as spatial signals that organise plant-microbe interactions. We discuss emerging tools and propose a cell-state framework linking plant and microbial cell states through local nutrient landscapes.
sciencedirect.com/science/ar…
Alexandre Marand retweeted
Save the date! More details to follow soon 😃
We are so excited to announce that applications are now being accepted for the 2027 Single-Cell Approaches in Plant Biology Gordon Research Conference!
Learn More and Apply Now!
grc.org/single-cell-approach…
ALT Image of a Gordon Research Conference webpage for “Decoding Plant Cell Biology Through Integrated Single Cell ‘Omics,” taking place August 8–13, 2027, at the University of Southern Maine in Portland, Maine. The page lists Nicola Patron and Marc Libault as chairs and Tatsuya Nobori and Shao-Shan Carol C. Huang as vice chairs. On the left is a collage of colorful microscopic images of plant cells.
A comprehensive understanding of heterosis has long been out of reach. Led by postdoc Luguang Jiang, we applied scifi-ATAC-seq to 🌽 inbreds and their recip hybrids, and identified a widespread loss of cell-type-specific ACRs in hybrid genomes 🧬 1/10
biorxiv.org/content/10.64898…
Taken together, we believe cell-specific regulatory mechanisms play a much larger role in heterosis than previously appreciated. Importantly, none of these discoveries would have been possible without single-cell genomics. 9/10
Congratulations to the team, @Jiang_luguang, @FabioGomezCano1, Andrew Luo, and Mark Minow for their enormous effort. We appreciate any feedback or insight the community is willing to offer. 10/10
Alexandre Marand retweeted
Excited to share Mario’s latest manuscript, now up on bioRxiv!
Using new single-locus multi-hormone reporters, Mario and the team dissected the spatially resolved Auxin-Cytokinin-Ethylene crosstalk hierarchy driving root growth inhibition in Arabidopsis. biorxiv.org/content/10.64898…