
Rouge Professional | BioE PhD Candidate @WormBuilder @KAUST_News | ChemE @UCBerkeley | Clown | Tweets on #SynBio #GlowWorms #GeneEditing #Failing
Synthetic Genome Biology Lab
Joined December 2020
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- Following542
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- Likes73
Mohammed D. Al Johani retweeted
Modular safe-harbor Transgene Insertion (MosTI) for targeted single-copy and extrachromosomal array integration in C. elegans. biorxiv.org/cgi/content/shor… #bioRxiv
Mohammed D. Al Johani retweeted
Happy to see our paper on piRNA-mediated silencing and transgenerational inheritance in C.elegans in print.
Thanks to Sam Gu @ Rutgers for a great collaboration! nature.com/articles/s41592-0…
Mohammed D. Al Johani retweeted
1/5 Our paper is out as a bioRxiv preprint. @sonia_elmouridi and @FaisalMAlkhaldi Like MosSCI, just better. Targeted single-copy and array integration synthesizing new and gradual improvements from the past 15 years across many labs. biorxiv.org/content/early/20…
Mohammed D. Al Johani retweeted
I made an opto cell line and it's the coolest thing ever!
I feel like a wizard pointing at cells and making them contract 🧙♂️.
Here is local RhoA activation by recruitment of LARG.
Mohammed D. Al Johani retweeted
That dorky sense of accomplishment when you finally find a restriction site for genotyping a knock-in that encodes a flexible linker dipeptide that does not introduce phosphorylatable amino acids. SfoI! In frame, encodes a gly-ala. AND cuts in Phusion HF buffer.
Mohammed D. Al Johani retweeted
Looking for a better negative selection marker for C. elegans transgenesis than peel-1? My postdoc and Master's student developed a simple histamine-based system that works like a charm. pubmed.ncbi.nlm.nih.gov/3343…
Mohammed D. Al Johani retweeted
Are genomes of identical twins really identical? "Our results indicate that allocations of cells during development shapes genomic differences between monozygotic twins." rdcu.be/cddS6 @NatureGenet
Mohammed D. Al Johani retweeted
I had to “sink or swim” in my undergrad lab, and because I swam, I assumed it was a good system. After having supportive mentors, I realize I could have learned so much more with proper guidance. Don’t let people sink just because it’s the way it was for you! #AcademicChatter
Mohammed D. Al Johani retweeted
Our review (@timlu & Zhong lab) on designing living materials using synthetic biology is out! We covered recent advances & prospects and summarized #synbio tools for programming smart living materials with various functionalities.
rdcu.be/ccNg0
nature.com/articles/s41578-0…
Mohammed D. Al Johani retweeted
1/n Rounding out the best of 2020 for our lab, newly published “Engineering Cell Fate: Applying synthetic biology to cellular reprogramming.” We review cellular reprogramming+#synbio Vision brought to life in vivid color by @nbwang22 and @beitz_adam
sciencedirect.com/science/ar…
Mohammed D. Al Johani retweeted
Introducing IN SITU GENOME SEQUENCING, a new technology to resolve DNA sequence🧬 and structure🔬
A team effort with @Andrew_C_Payne, @PaulReginato, @eboyden3, @JD_Buenrostro, and Fei Chen
science.sciencemag.org/conte…
This is how it works: (1/8)
Mohammed D. Al Johani retweeted
is my code fast? no. but is it well documented? no. but does it work? also no.
Mohammed D. Al Johani retweeted
40 million years ago, ticks stole a gene from bacteria. Today, they use the enzyme that gene makes to fight off bacteria on our skin.
sciencenews.org/article/how-…






















