@LukeshGroup

Lukesh Group: Chemical Biology and Medicinal Chemistry at Wake Forest University

 Winston-Salem, NC
lukeshjc.sites.wfu.edu
Joined September 2019
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  • Following291
  • Followers305
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The Lukesh Group in the Department of Chemistry at Wake Forest University is seeking a highly motivated Postdoctoral Research Associate to join our team. Interested candidates can learn more and apply at the link below. wfu.wd1.myworkdayjobs.com/St…
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Excited to share our new paper in @J_A_C_S! Congrats to Ravi and Rynne for leading this work developing stimulus-responsive donors that enable controlled access to reactive selenium species long proposed but elusive in redox biology. pubs.acs.org/doi/10.1021/jac…

Stimulus-Responsive Perselenide, Thioselenide, and Selenosulfide Donors for Reactive Selenium...

Abstract. Reactive selenium species (RSeS), including perselenides (RSeSeH), thioselenides (RSSeH), and selenosulfides (RSeSH), have long been proposed as

pubs.acs.org
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Excited to share Changlei's comprehensive review on self-reporting H₂S donors - now available! Check it out below. mdpi.com/2624-8549/7/4/116

Self-Reporting H2S Donors: Integrating H2S Release with Real-Time Fluorescence Detection

Hydrogen sulfide (H2S), once regarded solely as a highly toxic gas, is now recognized as a crucial signaling molecule in plants, bacteria, and mammals. In humans, H2S signaling plays a role in...

mdpi.com
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Sarah Spigelmyer received the Chemistry Department's Outstanding First Year Grad Student Award, Devin Weaver won the Outstanding TA Award, & recent graduate Jesse Ingram (not pictured) received the Outstanding Senior Grad Student Award. Congrats to all!
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Help us welcome our newest faculty member and learn about her research! #wakedowntown
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Check out Changlei's latest work on esterase-activated donors that self-report their real-time cellular H2S delivery by forming a fluorogenic byproduct. Hot off the press in ACS Chemical Biology! pubs.acs.org/doi/10.1021/acs…

Esterase-Activated Hydrogen Sulfide Donors with Self-Reporting Fluorescence Properties and Highly...

Abstract. Hydrogen sulfide (H2S) has emerged as a significant biomolecule with diverse activities, akin to other gaseous signaling molecules such as nitric

pubs.acs.org
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Rynne's review of Chemical Tools for Hydrogen Selenide Donation and Detection is out in @Molecules_MDPI! Many thanks to Prof. Ming Wang for the invitation to contribute to this special issue on Organosulfur and Organoselenium Chemistry. doi.org/10.3390/molecules291…

An Examination of Chemical Tools for Hydrogen Selenide Donation and Detection

Hydrogen selenide (H2Se) is an emerging biomolecule of interest with similar properties to that of other gaseous signaling molecules (i.e., gasotransmitters that include nitric oxide, carbon monoxi...

mdpi.com
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We are looking to hire postdoctoral colleagues with a strong background in organic synthesis and chemical biology research. More information can be found at the link below. Please help spread the word! #ChemPostdoc @Chemjobber wfu.wd1.myworkdayjobs.com/St…
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It's official! Excited to share that our lab has been awarded an @NIH @NIGMS #R35 #ESI #MIRA! This 5-year grant will support our work investigating the biomedical applications of reactive sulfur and selenium species. Congratulations team!
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It was a special honor having the opportunity to hood Dr. Zhu at yesterday’s graduation! #WFUGrad
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Join us to celebrate the research accomplishments of these undergraduate students.
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Excited to share our groups very first @J_A_C_S paper, which reports on a new donor platform with two distinct (and highly controllable) pathways for H2S release. A great effort led by Qiwei and other @WakeChemistry students! pubs.acs.org/doi/full/10.102…

An ROS-Responsive Donor That Self-Reports Its H2S Delivery by Forming a Benzoxazole-Based Fluorop...

Abstract. Hydrogen sulfide (H2S), an endogenous signaling molecule, is known to play a pivotal role in neuroprotection, vasodilation, and hormonal regulati

pubs.acs.org
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Please join us!
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A great group with outstanding students and state-of-the-art facilities! Come join me @WakeChemistry! #ChemFacultyJobs
WFU Chemistry@WakeChemistry5 Sep 2023
We're hiring! The Chemistry Department at WFU is searching for two tenure-track positions. More details can be found here: chemistry.wfu.edu/announceme…
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Congratulations Changlei (PhD #4 from the Lukesh group)! The @Hsu_Lab_UVa is about to add an outstanding scientist and colleague to their group!
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Join us as we celebrate the research accomplishments of graduate student Changlei Zhu. @LukeshGroup
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John Lukesh retweeted
Troy Stich@pinenut66619 Jul 2023
Hey friends, Wake Forest will be announcing soon that we are hiring for two tenure-track positions. One in biochemistry, and one in experimental physical chemistry. Please look to this space and the departmental website for details as they come on line. Feel free to reach out.
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Special moment when you get to present in the same section as your former advisor Ronald Raines at APS #peptides2023. Working on some polymer projects to complete the set with @SwagerGroup and @AdronovGroup
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We are so proud of this group! H How many pictures does it take to get all of our graduate degree recipients and their faculty mentors to fit in the shot and look at the camera together? #INFINITE
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Contrats Dr. Hu and Dr. Hankins!
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